Compounds > 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline

Page last updated: 2024-09-03

7,8-dichloro-1,2,3,4-tetrahydroisoquinoline and 4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole

7,8-dichloro-1,2,3,4-tetrahydroisoquinoline has been researched along with 4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole in 5 studies

Compound Research Comparison

Studies (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline)	Trials (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline)	Recent Studies (post-2010) (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline)	Studies (4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole)	Trials (4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole)	Recent Studies (post-2010) (4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole)
79	0	0	10	0	0

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Caldwell, TM; Criscione, KR; Grunewald, GL; Li, Q	2
Borchardt, RT; Caldwell, TM; Criscione, KR; Grunewald, GL; Li, Q; Slavica, M; Wang, W	1
Brosnihan, KB; Chatelain, RE; Dardik, BN; Manniello, MJ; Rizzo, M	1
Atobe, M; Kariya, T; Kubota, M; Nakagawara, M	1

Other Studies

5 other study(ies) available for 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline and 4,9-dihydro-7-methoxy-3h-pyrido(3,4b)indole

Article	Year
Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor. Journal of medicinal chemistry, 1999, Aug-26, Volume: 42, Issue:17 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines	1999
Synthesis and biochemical evaluation of 3-fluoromethyl-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor. Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18 Topics: Adrenal Glands; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding, Competitive; Blood-Brain Barrier; Cattle; Clonidine; Enzyme Inhibitors; Fluorine Compounds; Isoquinolines; Models, Molecular; Permeability; Phenylethanolamine N-Methyltransferase	1999
Synthesis and evaluation of 4-fluoro-8-substituted-2,3,4,5-tetrahydro-1H-2-benzazapines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor. Journal of medicinal chemistry, 2001, Aug-16, Volume: 44, Issue:17 Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Cerebral Cortex; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Male; Models, Molecular; Phentolamine; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship	2001
Antihypertensive effects of CGS 19281A, an inhibitor of phenylethanolamine-N-methyltransferase. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbolines; Catecholamines; Desoxycorticosterone; Dose-Response Relationship, Drug; Isoquinolines; Phenylethanolamine N-Methyltransferase; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines	1990
Effect of phenylethanolamine N-methyltransferase inhibitor, CGS19281A, on the alpha-2-adrenoceptor function in the hypothalamus of rats in comparison with SKF29661, SKF64139 and yohimbine. Neuropsychobiology, 1996, Volume: 34, Issue:2 Topics: Animals; Carbolines; Clonidine; Hypothalamus; Isoquinolines; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Tetrahydroisoquinolines; Yohimbine	1996