Page last updated: 2024-09-03

7,8-(methylenedioxy)-14-hydroxyberbane and clonidine

7,8-(methylenedioxy)-14-hydroxyberbane has been researched along with clonidine in 8 studies

Compound Research Comparison

Studies
(7,8-(methylenedioxy)-14-hydroxyberbane)
Trials
(7,8-(methylenedioxy)-14-hydroxyberbane)
Recent Studies (post-2010)
(7,8-(methylenedioxy)-14-hydroxyberbane)
Studies
(clonidine)
Trials
(clonidine)
Recent Studies (post-2010) (clonidine)
400013,6922,0441,394

Protein Interaction Comparison

ProteinTaxonomy7,8-(methylenedioxy)-14-hydroxyberbane (IC50)clonidine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.101
Alpha-2B adrenergic receptorHomo sapiens (human)0.0353
Alpha-2C adrenergic receptorHomo sapiens (human)0.0115
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)5.365
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-1D adrenergic receptorHomo sapiens (human)1.21
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)5.365
Alpha-2A adrenergic receptorBos taurus (cattle)0.002
NischarinRattus norvegicus (Norway rat)0.3662

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sperlágh, B; Vizi, ES1
Bartha, L; Hársing, LG; Kiem, DT; Makara, GB1
Bence, J; Körmöczy, PS; Kurcz, M; Kuthy, K; Várkonyi, P1
Dóda, M; Vizi, ES1
Baranyi, M; Mike, A; Milusheva, E; Vizi, ES; Zelles, T1
Kovács, KJ; Makara, GB1
Kiem, DT; Makara, GB; Vizi, ES1
Baranyi, M; Bencsics, A; Hashim, A; Lajtha, A; Sershen, H; Vizi, ES1

Other Studies

8 other study(ies) available for 7,8-(methylenedioxy)-14-hydroxyberbane and clonidine

ArticleYear
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation?
    Neuroscience, 1992, Volume: 51, Issue:1

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine

1992
Reevaluation of the role of alpha 2-adrenoreceptors in morphine-stimulated release of growth hormone.
    Neuroendocrinology, 1991, Volume: 53, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Growth Hormone; Male; Morphine; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Testosterone; Yohimbine

1991
The effect of CH-38083 on the motility and passive avoidance behavior of male Sprague-Dawley rats.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Berberine; Berberine Alkaloids; Clonidine; Male; Motor Activity; Rats; Rats, Inbred Strains

1990
Effect of CH-38083, a selective antagonist of alpha 2-adrenoceptors, on renal sympathetic function.
    Neuropharmacology, 1989, Volume: 28, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Berberine Alkaloids; Blood Pressure; Cats; Clonidine; Dimethylphenylpiperazinium Iodide; Dioxanes; Female; Idazoxan; Kidney; Male; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Xylazine

1989
Release of acetylcholine and noradrenaline from the cholinergic and adrenergic afferents in rat hippocampal CA1, CA3 and dentate gyrus regions.
    The European journal of neuroscience, 1994, Feb-01, Volume: 6, Issue:2

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Atropine; Berberine; Choline; Clonidine; Hippocampus; In Vitro Techniques; Luminescent Measurements; Male; Norepinephrine; Oxotremorine; Physostigmine; Pyramidal Tracts; Rats; Rats, Wistar; Tritium

1994
Factors from the paraventricular nucleus mediate inhibitory effect of alpha-2-adrenergic drugs on ACTH secretion.
    Neuroendocrinology, 1993, Volume: 57, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Berberine; Clonidine; In Vitro Techniques; Male; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Anterior; Rats; Rats, Wistar; Receptors, Adrenergic, alpha

1993
Hypothalamic alpha 2A-adrenoceptors stimulate growth hormone release in the rat.
    European journal of pharmacology, 1995, Dec-04, Volume: 287, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Dioxanes; Growth Hormone-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Male; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Somatostatin

1995
Dopamine, as well as norepinephrine, is a link between noradrenergic nerve terminals and splenocytes.
    Brain research, 1997, Jul-04, Volume: 761, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Berberine; Clonidine; Desipramine; Dopamine; Dopamine Antagonists; Electric Stimulation; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Presynaptic Terminals; Rats; Rats, Wistar; Spleen; Sulpiride; Sympathomimetics; Tritium

1997