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7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol and 9,10-dimethyl-1,2-benzanthracene

7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol has been researched along with 9,10-dimethyl-1,2-benzanthracene in 7 studies

*9,10-Dimethyl-1,2-benzanthracene: Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen. [MeSH]

*9,10-Dimethyl-1,2-benzanthracene: Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen. [MeSH]

Compound Research Comparison

Studies
(7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol)
Trials
(7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol)
Recent Studies (post-2010)
(7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol)
Studies
(9,10-dimethyl-1,2-benzanthracene)
Trials
(9,10-dimethyl-1,2-benzanthracene)
Recent Studies (post-2010) (9,10-dimethyl-1,2-benzanthracene)
8006,01010772

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartsch, H; Camus, AM; Grover, PL; Malaveille, C; Pyerin, WG; Sims, P1
O'Connor, JM; Schnitz, AR; Squibb, KS1
Bilolikar, DS; Chen, JX; DiGiovanni, J; Harvey, RG; Morris, RJ; Slaga, TJ; Tang, MS; Viaje, A; Vulimiri, SV1
Furukawa, M; Gonzalez, FJ; Miyata, M; Motoki, K; Tamura, E; Yamazoe, Y1
Flesher, JW; Horn, J; Lehner, AF1
Gopalakrishnakone, P; Ignacimuthu, S; Samy, RP1
Birtwistle, J; Bunce, CM; Chipman, JK; Davies, NJ; Green, RM; Hayden, RE; Khanim, FL; Pearce, C; Ride, JP; Schrewe, H; Wake, N1

Other Studies

7 other study(ies) available for 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol and 9,10-dimethyl-1,2-benzanthracene

ArticleYear
Mutagenicity of benzo[a]pyrene 7,8-dihydrodiol and 7,12-dimethylbenz[a]anthracene 3,4-dihydrodiol in S. typhimurium mediated by microsomes from rat liver and mouse skin.
    Chemico-biological interactions, 1980, Volume: 32, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; Female; Male; Mice; Microsomes; Microsomes, Liver; Mutagenicity Tests; Rats; Salmonella typhimurium; Skin

1980
Time-varying conjugation of 7,12-dimethylbenz[a]anthracene metabolites in rainbow trout (Oncorhynchus mykiss).
    Toxicology and applied pharmacology, 1993, Volume: 121, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Arylsulfatases; Bile; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Hydrolysis; Kinetics; Liver; Sulfates; Trout

1993
Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Carcinogens; Codon; DNA; DNA Adducts; Epidermis; Female; Genes, ras; Mice; Mice, Inbred SENCAR; Mutation; Papilloma; Skin Neoplasms; Stereoisomerism

2000
Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[a]anthracene-induced developmental toxicity.
    Biochemical pharmacology, 2002, Mar-15, Volume: 63, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinogens; Cell Survival; Embryo, Mammalian; Epoxide Hydrolases; Fibroblasts; Mice; Mice, Inbred C57BL

2002
Rapid induction of mammary cancer by repeated subcutaneous injection of the trans-3,4-dihydrodiol of 7,12-dimethylbenz[a]anthracene in the female Sprague-Dawley rat.
    Cancer letters, 2005, Apr-08, Volume: 220, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Sarcoma; Solubility; Time Factors

2005
Anti-tumor promoting potential of luteolin against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
    Chemico-biological interactions, 2006, Dec-01, Volume: 164, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Catalase; Female; Glutathione Peroxidase; Lipid Peroxides; Luteolin; Mammary Neoplasms, Experimental; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Treatment Outcome

2006
The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.
    Mutation research, 2009, Mar-09, Volume: 662, Issue:1-2

    Topics: 3-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Aldo-Keto Reductase Family 1 Member C3; Cell Differentiation; Cell Line, Tumor; DNA Damage; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Glycophorins; Hemoglobins; Humans; Hydroxyprostaglandin Dehydrogenases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Oxidative Stress; Stem Cells

2009