7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid has been researched along with mocetinostat in 5 studies
| Studies (7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid) | Trials (7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid) | Recent Studies (post-2010) (7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid) | Studies (mocetinostat) | Trials (mocetinostat) | Recent Studies (post-2010) (mocetinostat) |
|---|---|---|---|---|---|
| 10 | 0 | 0 | 21,735 | 390 | 8,606 |
| Protein | Taxonomy | 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid (IC50) | mocetinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.7851 | |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | 0.022 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.57 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.102 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.102 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.3433 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3537 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.6386 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.6725 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.045 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anglin, CP; Bremer, M; Djuric, SW; Docter, SH; Fretland, DJ; Isakson, P; Paulson, SK; Penning, TD; Widomski, DL; Yu, S | 1 |
| Baron, DA; Fretland, DJ; Gokhale, R; Mathur, L; Paulson, SK; Stolzenbach, J | 1 |
| Anglin, CP; Djuric, SW; Fretland, DJ; Penning, TD; Widomski, DL; Yu, S | 1 |
| Anglin, CP; Baron, DA; Fretland, DJ; Maziasz, T; Smith, PF; Widomski, D | 1 |
| Anglin, C; Baron, D; Bhatt, R; Chauhan, K; Falck, J; Fretland, D; Widomski, D | 1 |
5 other study(ies) available for 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid and mocetinostat
| Article | Year |
|---|---|
Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: impact upon leukotriene B4- and 12(R)-HETE-mediated events.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Biomarkers; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Injections, Intradermal; Leukotriene B4; Male; Membrane Potentials; Neutrophils; Peroxidase; Receptors, Leukotriene B4; Skin | 1995 |
Dermal inflammation in primates, mice, and guinea pigs: attenuation by second-generation leukotriene B4 receptor antagonist, SC-53228.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Disease Models, Animal; Drug Eruptions; Drug Evaluation, Preclinical; Ear, External; Edema; Female; Gels; Guinea Pigs; Humans; Male; Mice; Peroxidase; Psoriasis; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate | 1995 |
Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146.
Topics: Administration, Oral; Animals; Benzamides; Benzopyrans; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Injections, Intradermal; Leukotriene B4; Male; Peroxidase; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; Thiazoles | 1993 |
Pharmacological activity of the second generation leukotriene B4 receptor antagonist, SC-53228: effects on acute colonic inflammation and hepatic function in rodents.
Topics: Acyl-CoA Oxidase; Animals; Benzamides; Benzopyrans; Colitis; Colon; Cytochrome P-450 Enzyme System; Gemfibrozil; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Oxidoreductases; Peroxidase; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene B4 | 1995 |
3(S)-hydroxy-leukotriene B4 is a potent granulocyte chemotaxin in the guinea pig dermis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Biomarkers; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Leukotriene B4; Male; Peroxidase; Skin | 1995 |