Page last updated: 2024-08-24

6-thioxanthine and mercaptopurine

6-thioxanthine has been researched along with mercaptopurine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T1
Desman, P; Fatino, A; Haney, O; Rafferty, RJ; Torres Hernandez, AX; Weeramange, CJ1
Baszczyňski, O; Eng, WS; Ferrero, RL; Guddat, LW; Hocková, D; Keough, DT; Naesens, L; Panjikar, S; Pohl, R; Rejman, D; Špaček, P; Wun, SJ1
Boulieu, R; Lenoir, A1
Bertocchi, M; Boulieu, R; Lenoir, A; Mornex, JF1
Chiou, SS; Wang, CC; Wu, SM1
Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K1
Arenas-Hernandez, M; Blaker, PA; Fairbanks, L; Irving, PM; Marinaki, AM; Sanderson, JD; Shobowale-Bakre, EA; Smith, MA1

Other Studies

8 other study(ies) available for 6-thioxanthine and mercaptopurine

ArticleYear
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship

2006
Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy.
    MedChemComm, 2019, Jan-01, Volume: 10, Issue:1

    Topics:

2019
    Journal of medicinal chemistry, 2021, 05-13, Volume: 64, Issue:9

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Molecular Dynamics Simulation; Organophosphonates; Pentosyltransferases; Prodrugs; Sequence Alignment; Structure-Activity Relationship

2021
Determination of thiopurine nucleotides in human lung tissue by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1995, Mar-10, Volume: 665, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Lung; Lung Transplantation; Mercaptopurine; Thioguanine; Xanthines

1995
Intracellular thiopurine nucleotides and azathioprine myelotoxicity in organ transplant patients.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Bone Marrow; Female; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Lung Transplantation; Male; Mercaptopurine; Middle Aged; Thioguanine; Xanthines

1997
Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis.
    Electrophoresis, 2005, Volume: 26, Issue:13

    Topics: Electrophoresis, Capillary; Guanosine; Humans; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Thioguanine; Thionucleosides; Xanthines

2005
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
    BMC biochemistry, 2007, May-18, Volume: 8

    Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

2007
Mechanism of allopurinol induced TPMT inhibition.
    Biochemical pharmacology, 2013, Aug-15, Volume: 86, Issue:4

    Topics: Adult; Allopurinol; Azathioprine; Case-Control Studies; Drug Therapy, Combination; Erythrocytes; Female; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methyltransferases; Oxypurinol; Prospective Studies; Xanthines

2013