6-thioguanosine has been researched along with dibenzo(a-l)pyrene* in 1 studies
1 other study(ies) available for 6-thioguanosine and dibenzo(a-l)pyrene
| Article | Year |
|---|---|
Determination of Mutational Spectra Induced by Environmental Toxicants in Complex Human Cell Populations.
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed in the environment and have potent mutagenic and carcinogenic activities. Studies of mutations induced by these compounds in human cells can help acquire an understanding of their mutagenic pathways. In this chapter, independent cultures of a human cell line expressing cytochrome P450 CYP1A1 (cell line MCL-5) were treated with benzo(a)pyrene (BaP) or dibenzo(a,l)pyrene (DBP), and mutants at the hypoxanthine phosphoribosyltransferase (HPRT) locus were selected en masse by 6-thioguanine resistance (6TG Topics: Benzo(a)pyrene; Benzopyrenes; Cell Line; Cytochrome P-450 Enzyme Inducers; Denaturing Gradient Gel Electrophoresis; Electrophoresis, Polyacrylamide Gel; Exons; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Mutagens; Mutation; Polymerase Chain Reaction; Thionucleosides; Workflow | 2020 |