6-phosphogluconolactone has been researched along with 2-2--azobis(2-amidinopropane)* in 1 studies
1 other study(ies) available for 6-phosphogluconolactone and 2-2--azobis(2-amidinopropane)
Article | Year |
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Peroxyl radicals modify 6-phosphogluconolactonase from Escherichia coli via oxidation of specific amino acids and aggregation which inhibits enzyme activity.
6-phosphogluconolactonase (6PGL) catalyzes the second reaction of the pentose phosphate pathway (PPP) converting 6-phosphogluconolactone to 6-phosphogluconate. The PPP is critical to the generation of NADPH and metabolic intermediates, but some of its components are susceptible to oxidative inactivation. Previous studies have characterized damage to the first (glucose-6-phosphate dehydrogenase) and third (6-phosphogluconate dehydrogenase) enzymes of the pathway, but no data are available for 6PGL. This knowledge gap is addressed here. Oxidation of Escherichia coli 6PGL by peroxyl radicals (ROO Topics: Amino Acids; Escherichia coli; NADP; Oxidation-Reduction | 2023 |