6-paradol has been researched along with guaiacol in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Bode, AM; Dong, Z; Ma, WY; Surh, YJ | 1 |
| Chung, WY; Jung, YJ; Lee, SS; Park, KK; Surh, YJ | 1 |
| Cha, IH; Joo, SY; Keum, YS; Kim, J; Lee, JM; Lee, KH; Lee, SS; Park, KK; Surh, YJ; Yook, JI; Yoon, JH | 1 |
| Ge, F; Li, J; Liang, J; Shi, Q; Tan, X; Tong, X | 1 |
| Chun, KS; Lee, E; Lee, LJ; Lee, SS; Park, KK; Surh, YJ | 1 |
| Shukla, Y; Singh, M | 1 |
| Affolter, M; le Coutre, J; Menozzi-Smarrito, C; Michlig, S; Munari, C; Riera, CE; Robert, F; Simon, SA; Vogel, H | 1 |
| Hirayama, H; Iwami, M; Mahmoud, FA; Shiina, T; Shima, T; Shimizu, Y; Sugita, J | 1 |
| Bucar, F; Gröblacher, B; Kunert, O; Maier, V | 1 |
| Aita, S; Hatano, T; Ikemoto, T; Iwanaga, T; Kameya, T; Kawai, Y; Saito, M; Sugita, J; Uchiwa, H; Yoneshiro, T | 1 |
| Kathiresan, S; Mariadoss, AV; Muthusamy, R | 1 |
| Haratake, A; Matsunaga, K; Setoguchi, S; Takata, J; Terada, K; Watase, D | 1 |
| Choi, JW; Chun, KH; Gaire, BP; Kim, SY; Kwon, OW; Park, SH; Shin, DY | 1 |
| Haratake, A; Matsunaga, K; Nagata-Akaho, N; Setoguchi, S; Takata, J; Watase, D | 1 |
| Chang, FR; Cheng, YB; El-Shazly, M; Hsieh, TJ; Hung, PH; Korinek, M; Tsai, YH; Wei, CK; Wu, YC | 1 |
| Ha, SK; Kim, HJ; Kim, IS; Nakamura, K; Rehman, SU; Yoo, HH | 1 |
| Hattori, H; Mitsunaga, T; Onwona-Agyeman, S; Yamauchi, K | 1 |
| Mitsunaga, T; Yamaguchi, K; Yamauchi, K | 1 |
| Abdallah, HM; El-Halawany, AM; Murad, HAS; Rafeeq, M | 1 |
| Hattori, H; Kita, M; Mitsunaga, T; Mori, T; Shibata, T | 1 |
| Contestabile, V; Mazzon, E; Schepici, G; Valeri, A | 1 |
| Abdou, RM; Aboushousha, T; El-Dine, RS; El-Maadawy, WH; El-Sayed, AM; El-Tanbouly, ND; Hassan, M | 1 |
2 review(s) available for 6-paradol and guaiacol
| Article | Year |
|---|---|
Cancer preventive properties of ginger: a brief review.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechols; Colonic Neoplasms; Fatty Alcohols; Gastrointestinal Neoplasms; Guaiacol; Humans; Ketones; Oils, Volatile; Skin Neoplasms; Tumor Cells, Cultured; Zingiber officinale | 2007 |
Ginger, a Possible Candidate for the Treatment of Dementias?
Topics: Catechols; Dementia; Drug Discovery; Fatty Alcohols; Guaiacol; Humans; Ketones; Models, Molecular; Plant Extracts; Protective Agents; Sesquiterpenes; Structure-Activity Relationship; Zingiber officinale | 2021 |
1 trial(s) available for 6-paradol and guaiacol
| Article | Year |
|---|---|
Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adult; Anthropometry; Calorimetry, Indirect; Cross-Over Studies; Diet; Dietary Supplements; Energy Metabolism; Fluorodeoxyglucose F18; Guaiacol; Humans; Ketones; Male; Plant Extracts; Positron-Emission Tomography; Seeds; Single-Blind Method; Temperature; Time Factors; Young Adult; Zingiberaceae | 2013 |
19 other study(ies) available for 6-paradol and guaiacol
| Article | Year |
|---|---|
Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol.
Topics: Animals; Anticarcinogenic Agents; Catechols; Cell Death; Cell Line; Cell Transformation, Neoplastic; DNA; Enzyme Induction; Epidermal Cells; Epidermal Growth Factor; Epidermis; Fatty Alcohols; Guaiacol; Ketones; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plants, Medicinal; Transcription Factor AP-1 | 2001 |
Antioxidative and antitumor promoting effects of [6]-paradol and its homologs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Carcinogens; DNA Damage; Ear, External; Edema; Epidermis; Female; Guaiacol; Hydrogen Peroxide; Ketones; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Peroxidase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Induction of apoptosis and caspase-3 activation by chemopreventive [6]-paradol and structurally related compounds in KB cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Survival; DNA Fragmentation; Enzyme Induction; Flow Cytometry; Guaiacol; Humans; Ketones; Mouth Neoplasms; Tumor Cells, Cultured | 2002 |
[Studies on the supercritical-CO2 fluid extraction and quality evaluation of ginger oils].
Topics: Carbon Dioxide; Chromatography, Supercritical Fluid; Distillation; Guaiacol; Ketones; Plant Oils; Zingiber officinale | 1999 |
Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechols; Dermatitis; Fatty Alcohols; Female; Guaiacol; HL-60 Cells; Humans; Ketones; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Papilloma; Plant Extracts; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zingiber officinale | 1999 |
Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.
Topics: Amides; Animals; Animals, Newborn; Catechols; Cells, Cultured; Female; Guaiacol; Humans; Ketones; Male; Mice; Mice, Knockout; Plant Oils; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Zanthoxylum; Zingiberaceae | 2009 |
Extract of grains of paradise and its active principle 6-paradol trigger thermogenesis of brown adipose tissue in rats.
Topics: Adipose Tissue, Brown; Animals; Electrophysiology; Guaiacol; Intercostal Nerves; Ketones; Male; Plant Extracts; Rats; Rats, Wistar; Thermogenesis; Zingiber officinale | 2011 |
Putative mycobacterial efflux inhibitors from the seeds of Aframomum melegueta.
Topics: Anti-Bacterial Agents; Catechols; Drug Resistance, Multiple; Ethidium; Fatty Alcohols; Guaiacol; Ketones; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Seeds; Zingiberaceae | 2012 |
Protective effects of [6]-paradol on histological lesions and immunohistochemical gene expression in DMBA induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cheek; Cricetinae; Guaiacol; Immunoenzyme Techniques; Ketones; Male; Mesocricetus; Mouth Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Zingiber officinale | 2013 |
Relationship between the acyl chain length of paradol analogues and their antiobesity activity following oral ingestion.
Topics: Adipose Tissue, Brown; Administration, Oral; Animals; Anti-Obesity Agents; Cells, Cultured; Guaiacol; Ion Channels; Ketones; Lipolysis; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Random Allocation; Rats, Sprague-Dawley; Structure-Activity Relationship; Uncoupling Protein 1; Up-Regulation | 2014 |
Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Line; Cell Proliferation; Cell Survival; Guaiacol; Interleukin-6; Ketones; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Microglia; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Reperfusion Injury; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Pharmacokinetics of Paradol Analogues Orally Administered to Rats.
Topics: Animals; Anti-Obesity Agents; Catechols; Fatty Alcohols; Guaiacol; Ketones; Male; Phenols; Rats; Rats, Sprague-Dawley | 2016 |
6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Blood Glucose; Catechols; Cell Line; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose; Glucose Tolerance Test; Guaiacol; Humans; Hyperglycemia; Immunoblotting; Ketones; Lipids; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Phosphorylation; Phytotherapy; Zingiber officinale | 2017 |
Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guaiacol; Humans; Ketones; Microsomes, Liver; Pharmaceutical Preparations; Recombinant Proteins; Zingiber officinale | 2017 |
Identification of vanilloid compounds in grains of paradise and their effects on sympathetic nerve activity.
Topics: Adipose Tissue, Brown; Animals; Catechols; Fatty Alcohols; Guaiacol; Humans; Ketones; Molecular Structure; Obesity; Plant Extracts; Rats; Seeds; Sympathetic Nervous System; Zingiberaceae | 2018 |
6-Paradol and its glucoside improve memory disorder in mice.
Topics: Animals; Calcium; Cyclic AMP Response Element-Binding Protein; Glucosides; Guaiacol; Humans; Ketones; Male; Memory; Memory Disorders; Mice; PC12 Cells; Phosphorylation; Plant Extracts; Rats; Receptor, trkA; Seeds; Signal Transduction; Zingiberaceae | 2020 |
Protective effect of 6-paradol in acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Glutathione; Guaiacol; Ketones; Male; Rats; Rats, Sprague-Dawley; Seeds; Zingiberaceae | 2021 |
6-Paradol Acts as a Potential Anti-obesity Vanilloid from Grains of Paradise.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Guaiacol; Ketones; Liver; Male; Mice; Molecular Structure; Obesity; Plant Extracts; Seeds; Weight Gain; Zingiberaceae | 2021 |
6-Paradol alleviates Diclofenac-induced acute kidney injury via autophagy enhancement-mediated by AMPK/AKT/mTOR and NLRP3 inflammasome pathways.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Autophagy; Diclofenac; Guaiacol; Inflammasomes; Ketones; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |