6-octadecynoic-acid has been researched along with 6-nonadecynoic-acid* in 1 studies
1 other study(ies) available for 6-octadecynoic-acid and 6-nonadecynoic-acid
Article | Year |
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Acetylenic acids inhibiting azole-resistant Candida albicans from Pentagonia gigantifolia.
Antifungal bioassay-guided isolation of the ethanol extract of the roots of Pentagonia gigantifolia yielded 6-octadecynoic acid (1) and the new 6-nonadecynoic acid (2). Compounds 1 and 2 inhibited the growth of fluconazole-susceptible and -resistant Candida albicans strains. Their antifungal potencies were comparable to those of amphotericin B and fluconazole. Of particular significance is the low cytotoxicity and specific activity of 1 and 2 against C. albicans. Topics: Amphotericin B; Antifungal Agents; Candida albicans; Drug Resistance, Microbial; Fatty Acids, Monounsaturated; Fluconazole; Gas Chromatography-Mass Spectrometry; Methylation; Microbial Sensitivity Tests; Molecular Structure; Peru; Plant Roots; Sphingolipids | 2003 |