Page last updated: 2024-08-26

6-n-propyluracil and uracil

6-n-propyluracil has been researched along with uracil in 27 studies

*Uracil: One of four nucleotide bases in the nucleic acid RNA. [MeSH]

*Uracil: One of four nucleotide bases in the nucleic acid RNA. [MeSH]

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's3 (11.11)18.2507
2000's15 (55.56)29.6817
2010's7 (25.93)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Gravel, C; Hawkes, R1
Gravel, C; Hawkes, R; Sasseville, R1
Manuel de Gandarias, J; Martinez, A; Zatón, A1
Ochoa de Aspuru, E; Zatón, AM1
Brent, GA; Friedman, TC; Jansen, E; Li, QL1
Matisoo-Smith, E; Turnbull, B1
Kamphuis, MM; Westerterp-Plantenga, MS1
Kirkmeyer, SV; Tepper, BJ1
Chopra, A; Essick, GK; Guest, S; McGlone, F1
Chainy, GB; Chattopadhyay, S; Das, K; Zaidi, G1
Bartoshuk, LM; Davidson, AC; Duffy, VB; Kidd, JR; Kidd, KK; Pakstis, AJ; Reed, DR; Snyder, DJ; Speed, WC1
Bartoshuk, LM; Basson, MD; Dichello, SZ; Duffy, VB; Panzini, L; Weiffenbach, JM1
Baker, TB; Cannon, DS; Caton, TC; Coon, H; Drayna, DT; Lawrence, DL; Leppert, MF; McMahon, WM; Piper, ME; Scholand, MB; Villegas, GM1
Macht, M; Mueller, J1
Bertelsen, S; Bierut, LJ; Bucholz, KK; Budde, JP; Dick, DM; Edenberg, HJ; Goate, AM; Hesselbrock, V; Hinrichs, AL; Kuperman, S; Rice, J; Saccone, N; Schuckit, MA; Stock, H; Wang, JC1
Ismail-Beigi, F; Kasturi, S1
Baranowski, J; Baranowski, T; Beltran, A; Islam, N; Missaghian, M; Sepulveda, KK; Watson, K1
Minobe, Y; Shiraishi, K; Umano, T; Yamasaki, K1
Hedge, AM; Sharma, A1
Coldwell, SE; Desai, H; Griffith, JW; Smutzer, G1
Cabras, T; Castagnola, M; Melis, M; Messana, I; Padiglia, A; Tepper, BJ; Tomassini Barbarossa, I1
Banni, S; Carta, G; Di Marzo, V; Melis, M; Muroni, P; Murru, E; Tomassini Barbarossa, I; Vacca, C; Zonza, A1
Cabras, T; Crnjar, R; Mattes, MZ; Melis, M; Messana, I; Tepper, BJ; Tomassini Barbarossa, I; Yousaf, NY1
Abumrad, NA; Love-Gregory, L; Mitreva, M; Ozdener, MH; Pepino, MY; Tomassini Barbarossa, I1
Ali, SA; Awad, SM; Mahgoub, S; Said, AM; Zohny, YM1
Ammann, J; Hartmann, C; Siegrist, M1
Barbarossa, IT; Fantola, G; Mastinu, M; Melis, M; Moroni, R; Pepino, MY; Pintus, S1

Trials

3 trial(s) available for 6-n-propyluracil and uracil

ArticleYear
PROP sensitivity affects macronutrient selection.
    Physiology & behavior, 2003, Volume: 79, Issue:2

    Topics: Adult; Appetite; Dietary Carbohydrates; Dietary Fats; Energy Intake; Food Preferences; Humans; Nutritional Physiological Phenomena; Philosophy; Taste; Uracil

2003
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2005, Volume: 7, Issue:6

    Topics: Adult; Analysis of Variance; Case-Control Studies; Chi-Square Distribution; Female; Humans; Male; Middle Aged; Phenylthiourea; Polymorphism, Genetic; Receptors, Cell Surface; Smoking; Taste; Taste Threshold; Uracil

2005
Responsiveness to 6-n-propylthiouracil (PROP) is associated with salivary levels of two specific basic proline-rich proteins in humans.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Adult; Carbonic Anhydrases; Female; Genotype; Humans; Male; Polymorphism, Genetic; Proteome; Receptors, G-Protein-Coupled; Saliva; Salivary Proline-Rich Proteins; Taste; Taste Perception; Uracil; Young Adult

2012

Other Studies

24 other study(ies) available for 6-n-propyluracil and uracil

ArticleYear
Maturation of the corpus callosum of the rat: I. Influence of thyroid hormones on the topography of callosal projections.
    The Journal of comparative neurology, 1990, Jan-01, Volume: 291, Issue:1

    Topics: Animals; Cerebral Cortex; Corpus Callosum; Cytoskeleton; Hypothyroidism; Immunohistochemistry; Intermediate Filaments; Rats; Rats, Inbred Strains; Thyroid Hormones; Uracil

1990
Maturation of the corpus callosum of the rat: II. Influence of thyroid hormones on the number and maturation of axons.
    The Journal of comparative neurology, 1990, Jan-01, Volume: 291, Issue:1

    Topics: Animals; Axons; Cell Count; Corpus Callosum; Hypothyroidism; Microscopy, Electron; Rats; Thyroid Hormones; Uracil

1990
The binding of thioureylene compounds to human serum albumin.
    Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16

    Topics: Antithyroid Agents; Diazepam; Humans; Propylthiouracil; Serum Albumin; Spectrophotometry, Ultraviolet; Thiouracil; Uracil; Warfarin

1988
Horseradish peroxidase inhibition by thiouracils.
    FEBS letters, 1995, Oct-30, Volume: 374, Issue:2

    Topics: Antithyroid Agents; Horseradish Peroxidase; Protein Binding; Spectrophotometry, Ultraviolet; Thiouracil; Uracil

1995
Regulation of prohormone convertase 1 (PC1) by thyroid hormone.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:1

    Topics: Alitretinoin; Animals; Antineoplastic Agents; Aspartic Acid Endopeptidases; Cells, Cultured; Gene Deletion; Gene Expression Regulation, Enzymologic; Genes, Reporter; Hypothyroidism; Luciferases; Male; Mutagenesis, Insertional; Oligonucleotides; Peptide Fragments; Pituitary Gland, Anterior; Promoter Regions, Genetic; Proprotein Convertases; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Transcription Factors; Tretinoin; Triiodothyronine; Uracil

2001
Taste sensitivity to 6-n-propylthiouracil predicts acceptance of bitter-tasting spinach in 3-6-y-old children.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:5

    Topics: Child, Preschool; Eating; Female; Food Preferences; Forecasting; Humans; Male; Spinacia oleracea; Taste; Taste Threshold; Uracil

2002
Understanding creaminess perception of dairy products using free-choice profiling and genetic responsivity to 6-n-propylthiouracil.
    Chemical senses, 2003, Volume: 28, Issue:6

    Topics: Adult; Dairy Products; Dietary Fats; Female; Food Preferences; Humans; Male; Middle Aged; Perception; Sodium Chloride; Taste; Taste Threshold; Uracil; Viscosity

2003
Lingual tactile acuity, taste perception, and the density and diameter of fungiform papillae in female subjects.
    Physiology & behavior, 2003, Volume: 80, Issue:2-3

    Topics: Adolescent; Adult; Asia; Dose-Response Relationship, Drug; Female; Humans; Pattern Recognition, Visual; Perception; Photic Stimulation; Psychophysics; Sensation; Sensory Thresholds; Statistics as Topic; Taste; Taste Buds; Taste Threshold; Tongue; Uracil; White People

2003
Effects of hypothyroidism induced by 6-n-propylthiouracil and its reversal by T3 on rat heart superoxide dismutase, catalase and lipid peroxidation.
    Indian journal of experimental biology, 2003, Volume: 41, Issue:8

    Topics: Animals; Catalase; Disease Models, Animal; Hyperthyroidism; Hypothyroidism; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardium; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase; Thyroxine; Triiodothyronine; Uracil

2003
Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake.
    Alcoholism, clinical and experimental research, 2004, Volume: 28, Issue:11

    Topics: Adult; Alcohol Drinking; Analysis of Variance; Chi-Square Distribution; Female; Genetic Variation; Genotype; Humans; Male; Middle Aged; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Uracil

2004
Association between 6-n-propylthiouracil (PROP) bitterness and colonic neoplasms.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:3

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Chi-Square Distribution; Cohort Studies; Colonic Neoplasms; Colonic Polyps; Diet; Feeding Behavior; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Probability; Prognosis; Risk Assessment; Sensitivity and Specificity; Sigmoidoscopy; Survival Rate; Taste; Taste Threshold; Uracil; Vegetables

2005
Increased negative emotional responses in PROP supertasters.
    Physiology & behavior, 2007, Feb-28, Volume: 90, Issue:2-3

    Topics: Adolescent; Adult; Analysis of Variance; Anger; Emotions; Fear; Female; Humans; Male; Middle Aged; Personality; Reference Values; Sex Factors; Taste; Taste Threshold; Uracil

2007
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Black or African American; Female; Genetic Variation; Haplotypes; Humans; Male; Mutation, Missense; Phenotype; Phenylthiourea; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Risk Factors; Taste; Uracil

2007
Effect of thyroid hormone on the distribution and activity of Na, K-ATPase in ventricular myocardium.
    Archives of biochemistry and biophysics, 2008, Jul-15, Volume: 475, Issue:2

    Topics: Actins; Animals; Caveolin 1; Caveolin 3; Cell Fractionation; Cholesterol; Heart Ventricles; Hyperthyroidism; Hypothyroidism; Myocardium; Rats; Sodium-Potassium-Exchanging ATPase; Thyroid Hormones; Thyroxine; Tissue Distribution; Triiodothyronine; Uracil

2008
Fruit and vegetables are similarly categorised by 8-13-year-old children.
    Public health nutrition, 2009, Volume: 12, Issue:2

    Topics: Adolescent; Body Mass Index; Child; Child Nutritional Physiological Phenomena; Cluster Analysis; Databases, Factual; Demography; Female; Fruit; Humans; Male; Mental Recall; Psychology, Child; Reproducibility of Results; Taste; Uracil; Vegetables

2009
Uterotrophic assay, Hershberger assay, and subacute oral toxicity study of 3-amino-1,2,4-triazole based on the Organization for Economic Co-operation and Development draft protocols.
    Archives of toxicology, 2009, Volume: 83, Issue:5

    Topics: Administration, Oral; Animals; Antithyroid Agents; Biological Assay; Body Weight; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Guidelines as Topic; Injections, Subcutaneous; Male; Orchiectomy; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thyrotropin; Thyroxine; Time Factors; Toxicity Tests, Acute; Triazoles; Triiodothyronine; Uracil; Uterus

2009
Genetic sensitivity to 6-n-propylthiouracil (PROP) as a screening tool for obesity and dental caries in children.
    The Journal of clinical pediatric dentistry, 2008,Winter, Volume: 33, Issue:2

    Topics: Analysis of Variance; Body Mass Index; Chi-Square Distribution; Child; Dental Caries; Dental Caries Susceptibility; Feeding Behavior; Female; Flavoring Agents; Food Preferences; Genetic Testing; Humans; Male; Obesity; Taste; Taste Perception; Uracil

2008
Validation of edible taste strips for identifying PROP taste recognition thresholds.
    The Laryngoscope, 2011, Volume: 121, Issue:6

    Topics: Adolescent; Adult; Female; Food Preferences; Genotype; Humans; Male; Middle Aged; Phenotype; Receptors, G-Protein-Coupled; Taste Threshold; Uracil; Young Adult

2011
Taste sensitivity to 6-n-propylthiouracil is associated with endocannabinoid plasma levels in normal-weight individuals.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:3

    Topics: Adult; Body Mass Index; Body Weight; Cognition; Endocannabinoids; Energy Intake; Feeding Behavior; Female; Humans; Hunger; Male; Satiation; Taste; Uracil

2013
Sensory perception of and salivary protein response to astringency as a function of the 6-n-propylthioural (PROP) bitter-taste phenotype.
    Physiology & behavior, 2017, 05-01, Volume: 173

    Topics: Adolescent; Adult; Analysis of Variance; Astringents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Fruit and Vegetable Juices; Humans; Male; Mass Spectrometry; Recognition, Psychology; Salivary Proteins and Peptides; Sex Characteristics; Tannins; Taste; Taste Perception; Uracil; Young Adult

2017
Variant in a common odorant-binding protein gene is associated with bitter sensitivity in people.
    Behavioural brain research, 2017, 06-30, Volume: 329

    Topics: Adult; Calcium; Epithelial Cells; Female; Food Preferences; Genotype; Humans; Lipocalins; Male; Odorants; Oleic Acid; Olfactory Mucosa; Psychophysics; Taste; Taste Perception; Uracil; Young Adult

2017
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents.
    Molecules (Basel, Switzerland), 2018, Nov-08, Volume: 23, Issue:11

    Topics: Animals; Antithyroid Agents; Binding Sites; Disease Models, Animal; Hydrophobic and Hydrophilic Interactions; Hyperthyroidism; Lactoperoxidase; Models, Molecular; Rats; Structure-Activity Relationship; Thiouracil; Triiodothyronine; Uracil

2018
A bitter taste in the mouth: The role of 6-n-propylthiouracil taster status and sex in food disgust sensitivity.
    Physiology & behavior, 2019, 05-15, Volume: 204

    Topics: Adolescent; Adult; Aged; Disgust; Female; Food; Humans; Male; Middle Aged; Sex Factors; Taste; Taste Threshold; Uracil; Young Adult

2019
Changes of Taste, Smell and Eating Behavior in Patients Undergoing Bariatric Surgery: Associations with PROP Phenotypes and Polymorphisms in the Odorant-Binding Protein OBPIIa and CD36 Receptor Genes.
    Nutrients, 2021, Jan-16, Volume: 13, Issue:1

    Topics: Adult; Bariatric Surgery; CD36 Antigens; Feeding Behavior; Female; Humans; Lipocalins; Male; Obesity, Morbid; Phenotype; Polymorphism, Genetic; Receptors, Antigen; Smell; Taste; Uracil

2021