6-methylthioguanine has been researched along with thioguanine anhydrous in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bostrom, BC; Canafax, DM; Carleton, BC; Erdmann, GR; Stafford, RJ; Steury, JC | 1 |
| Bostrom, BC; Canafax, DM; Erdmann, GR; France, LA | 1 |
| Saneyoshi, M; Sung, SC | 2 |
| Dooley, T; Maddocks, JL | 1 |
| Edwards, M; Mace, R; Moulton, DC; Swann, PF; Waters, TR; Xu, YZ; Zheng, Q | 1 |
| Swann, PF; Waters, TR | 1 |
| Lennard, L; Lilleyman, JS; Rowland, K | 1 |
| Berg, JD; Cooper, SC; Ford, LT; Lewis, MJ | 1 |
| Adams, H; Aiertza, MK; Burrell, AJ; Edmont, D; Hammond, DM; Hornillo-Araujo, AR; Margison, GP; Shibata, T; Williams, DM | 1 |
| Wang, H; Wang, Y | 1 |
| O'Connor, TR; Wang, Y; Yuan, B | 1 |
| Dai, X; Wang, Y; You, C; Yuan, B | 1 |
| Angelberger, S; Bar-Meir, S; Dilger, K; Greinwald, R; Herrlinger, KR; Lukas, M; Mueller, R; Petritsch, W; Reinisch, W; Schaeffeler, E; Schwab, M; Shonova, O; Stange, EF; Teml, A | 1 |
| Bahrehmand, F; Bashiri, H; Kiani, A; Pourmotabbed, T; Tanhapour, M; Vaisi-Raygani, A; Zobeiri, M | 1 |
15 other study(ies) available for 6-methylthioguanine and thioguanine anhydrous
| Article | Year |
|---|---|
Reversed-phase high-performance liquid chromatographic approach to determine total lymphocyte concentrations of 6-thioguanine, methylmercaptopurine and methylthioguanine in humans.
Topics: Chromatography, High Pressure Liquid; Fluorescence; Humans; Lymphocytes; Mercaptopurine; Thioguanine | 1991 |
A reversed phase high performance liquid chromatography approach in determining total red blood cell concentrations of 6-thioguanine, 6-mercaptopurine, methylthioguanine, and methylmercaptopurine in a patient receiving thiopurine therapy.
Topics: Child; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Mercaptopurine; Microchemistry; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality Control; Thioguanine | 1990 |
Effect of 9-alkyl derivatives of 6-methylthioguanine on brain specific binding of [3H]diazepam.
Topics: Animals; Brain; Diazepam; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thioguanine | 1986 |
High-performance liquid chromatographic assay of 6-methylthioguanine, a major metabolite of 6-thioguanine, in urine.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Humans; Methylation; Spectrometry, Fluorescence; Thioguanine | 1985 |
Effect of synthetic purines and purine nucleosides on [3H]diazepam binding in brain.
Topics: Aging; Animals; Binding, Competitive; Brain; Diazepam; In Vitro Techniques; Male; Membranes; Purine Nucleosides; Purines; Rats; Rats, Inbred Strains; Synaptosomes; Thioguanine | 1982 |
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.
Topics: Animals; Antimetabolites, Antineoplastic; Base Composition; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Repair; DNA Replication; HeLa Cells; Humans; Methylation; Molecular Sequence Data; S-Adenosylmethionine; Thioguanine | 1996 |
Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine.
Topics: Base Composition; Base Sequence; Cell Extracts; DNA-Binding Proteins; HeLa Cells; Humans; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Structure-Activity Relationship; Thioguanine; Tumor Cells, Cultured | 1997 |
High-performance liquid chromatographic assay of methylthioguanine nucleotide.
Topics: Antimetabolites, Antineoplastic; Child; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Thioguanine | 1998 |
Reference intervals for thiopurine S-methyltransferase activity in red blood cells using 6-thioguanine as substrate and rapid non-extraction liquid chromatography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Male; Methyltransferases; Middle Aged; Phenotype; Substrate Specificity; Thioguanine | 2004 |
The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine.
Topics: Crystallography, X-Ray; Guanine; Humans; Hydrogen-Ion Concentration; Molecular Structure; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidines; Pyrroles; Substrate Specificity; Thioguanine | 2006 |
LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine.
Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA Mismatch Repair; DNA, Neoplasm; Genome, Human; Humans; Neoplasms; Nitrogen Isotopes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tandem Mass Spectrometry; Thioguanine | 2010 |
6-Thioguanine and S⁶-methylthioguanine are mutagenic in human cells.
Topics: Antineoplastic Agents; Base Sequence; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA; Genetic Vectors; Humans; Immunosuppressive Agents; Molecular Sequence Data; Mutagenesis; Mutagens; Thioguanine | 2010 |
Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells.
Topics: Antimetabolites, Antineoplastic; Chromatography, Liquid; DNA; DNA Damage; DNA Repair; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Guanine; HEK293 Cells; Humans; In Vitro Techniques; Models, Chemical; Mutagenesis; Mutation; Phosphorylation; RNA; Tandem Mass Spectrometry; Thioguanine; Transcription, Genetic; Viral Proteins | 2012 |
Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels.
Topics: Adolescent; Adult; Aged; Azathioprine; Biomarkers; Crohn Disease; Drug Administration Schedule; Drug Monitoring; Endoscopy, Gastrointestinal; Female; Guanine Nucleotides; Humans; Immunosuppressive Agents; Intestinal Mucosa; Male; Middle Aged; Recurrence; ROC Curve; Severity of Illness Index; Thioguanine; Thioinosine; Thionucleotides; Treatment Outcome; Young Adult | 2013 |
Pharmacogenetics of drug metabolizing enzyme: thiopurine methyl transferase phenotypes and multidrug resistance 1 gene polymorphism in inflammatory bowel disease.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; Body Mass Index; Case-Control Studies; Chromatography, High Pressure Liquid; Demography; Female; Humans; Inflammatory Bowel Diseases; Male; Methyltransferases; Odds Ratio; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Risk Factors; Thioguanine | 2016 |