6-methylsulfinylhexyl-isothiocyanate and isothiocyanic-acid

Autophagy is a fundamental catabolic process of cellular survival. The role of autophagy in cancer is highly complex: in the early stages of neoplastic transformation, it can act as a tumor suppressor avoiding the accumulation of proteins, damaged organelles, and reactive oxygen species (ROS), while during the advanced stages of cancer, autophagy is exploited by cancer cells to survive under starvation. 6-(Methylsulfonyl) hexyl isothiocyanate (6-MITC) is the most interesting compound in the

Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cytostatic Agents; HL-60 Cells; Humans; Isothiocyanates; Leukemia; Reactive Oxygen Species