Page last updated: 2024-08-21

6-methylsalicylic acid and salicylates

6-methylsalicylic acid has been researched along with salicylates in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (12.00)	18.7374
1990's	4 (16.00)	18.2507
2000's	10 (40.00)	29.6817
2010's	7 (28.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Jordan, PM; Spencer, JB	1
Gaucher, GM; Jones, A; Lam, KS; Scott, RE	1
Brune, K; Green, P; Rainsford, KD; Schweitzer, A; Whitehouse, MW	1
Bedford, DJ; Hopwood, DA; Khosla, C; Schweizer, E	1
Ebizuka, Y; Fujii, I; Gomi, K; Ono, Y; Sankawa, U; Tada, H	1
Barr, PJ; Betlach, MC; Kealey, JT; Liu, L; Santi, DV	1
Altier, DJ; Barbour, E; Cigan, AL; Scelonge, CJ; Yalpani, N	1
Staunton, J; Weissman, KJ	1
Light, RJ	1
Jørgensen, CG; Laursen, JB; Nielsen, J	1
ANDREWS, MM	1
Jia, XY; Liu, W; Qu, XD; Shao, L; Tang, GL; Tang, J; Tian, ZH; Zhao, QF	1
Andrésson, OS; Lantz, AE; Nielsen, J; Nielsen, ML; Wattanachaisaereekul, S	1
Eguchi, T; Hirayama, T; Kasama, Y; Kudo, F	1
Jónsdóttir, SO; Kouskoumvekaki, I; Olsson, L; Panagiotou, G; Yang, Z	1
Lantz, AE; Nielsen, J; Nielsen, ML; Wattanachaisaereekul, S	1
Lumbsch, HT; Schmitt, I	1
Fujii, I	1
Bi, Y; Ding, W; He, Q; Lei, C; Liu, W; Zhang, Q	1
Gotfredsen, CH; Holm, DK; Jarczynska, ZD; Klitgaard, A; Knudsen, PB; Larsen, TO; Mortensen, UH; Nielsen, KF; Petersen, LM	1
Bruno, KS; Guo, CJ; Sun, WW; Wang, CC	1
Frandsen, RJ; Frisvad, JC; Holm, DK; Klitgaard, A; Knudsen, PB; Nielsen, KF	1
Gotfredsen, CH; Holm, DK; Larsen, TO; Mortensen, UH; Petersen, LM	1
Connolly, J; Havemann, J; Huang, F; Leadlay, PF; Parascandolo, JS; Potter, HK; Riva, E; Song, L; Tosin, M; Wilkening, I	1
Jarczynska, ZD; Kirchner, FH; Mortensen, UH; Nielsen, ML; Nødvig, CS; Pagels, N; Rendsvig, JKH; Strucko, T; Viana, VR	1

Reviews

2 review(s) available for 6-methylsalicylic acid and salicylates

Article	Year
Polyketide biosynthesis: a millennium review. Natural product reports, 2001, Volume: 18, Issue:4 Topics: Bacteria; Biological Factors; Catalysis; Erythromycin; Fatty Acids; Genetic Engineering; Isotope Labeling; Ligases; Lovastatin; Models, Theoretical; Molecular Structure; Multienzyme Complexes; Mutagenesis; Proteins; Salicylates; Stereoisomerism; Substrate Specificity	2001
Functional analysis of fungal polyketide biosynthesis genes. The Journal of antibiotics, 2010, Volume: 63, Issue:5 Topics: Alternaria; Aspergillus; Genes, Fungal; Macrolides; Peptide Synthases; Polyketide Synthases; Salicylates	2010

Other Studies

23 other study(ies) available for 6-methylsalicylic acid and salicylates

Article	Year
Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum. The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3) Topics: Acetone; Acyltransferases; Cell Division; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Ligases; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Oxidoreductases; Penicillium; Pyrones; Salicylates; Substrate Specificity	1992
Manganese and antibiotic biosynthesis. I. A specific manganese requirement for patulin production in Penicillium urticae. Canadian journal of microbiology, 1986, Volume: 32, Issue:3 Topics: Acyltransferases; Culture Media; Dose-Response Relationship, Drug; Ligases; Manganese; Metals; Multienzyme Complexes; Oxidoreductases; Patulin; Penicillium; Pyrans; Salicylates	1986
Bio-distribution in rats of some salicylates with low gastric ulcerogenicity. Agents and actions, 1980, Volume: 10, Issue:5 Topics: Animals; Aspirin; Male; Rats; Salicylates; Stomach Ulcer; Tissue Distribution	1980
Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2). Journal of bacteriology, 1995, Volume: 177, Issue:15 Topics: Amino Acid Sequence; Base Sequence; DNA, Fungal; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Models, Genetic; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Penicillium; Plasmids; Salicylates; Streptomyces	1995
Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression. Molecular & general genetics : MGG, 1996, Nov-27, Volume: 253, Issue:1-2 Topics: Acyltransferases; Amino Acid Sequence; Aspergillus; Aspergillus nidulans; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; Gene Library; Genes, Fungal; Ligases; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Oxidoreductases; Salicylates; Sequence Homology, Amino Acid; Transformation, Genetic	1996
Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts. Proceedings of the National Academy of Sciences of the United States of America, 1998, Jan-20, Volume: 95, Issue:2 Topics: Escherichia coli; Genes, Bacterial; Humans; Multienzyme Complexes; Saccharomyces cerevisiae; Salicylates	1998
Production of 6-methylsalicylic acid by expression of a fungal polyketide synthase activates disease resistance in tobacco. The Plant cell, 2001, Volume: 13, Issue:6 Topics: beta-Glucosidase; Chitinases; Glucan 1,3-beta-Glucosidase; Molecular Mimicry; Multienzyme Complexes; Nicotiana; Penicillium; Phenotype; Plant Diseases; Plant Proteins; Plants, Genetically Modified; Plants, Toxic; Salicylates; Tobacco Mosaic Virus; Transformation, Genetic	2001
Yeast hydroxy fatty acids and fungal polyketides: lessons learned from the Konrad Bloch laboratory. Biochemical and biophysical research communications, 2002, Apr-19, Volume: 292, Issue:5 Topics: Anti-Bacterial Agents; Biochemistry; Fatty Acids; Fungi; History, 20th Century; Hydroxy Acids; Saccharomyces; Salicylates; United States	2002
First synthesis of racemic saphenamycin and its enantiomers. investigation of biological activity. Bioorganic & medicinal chemistry, 2003, Mar-06, Volume: 11, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Models, Molecular; Phenazines; Salicylates; Stereoisomerism	2003
The relative potencies of some substituted salicylic acids as metabolic stimulants in the intact rat. British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:4 Topics: Animals; Benzoates; Central Nervous System Agents; Central Nervous System Stimulants; Hippurates; Hydroxybenzoates; Male; Mesalamine; Metabolism; ortho-Aminobenzoates; Rats; Salicylates	1958
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis. Chemistry & biology, 2006, Volume: 13, Issue:6 Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Carbohydrate Metabolism; Chlorine; Chromatography, High Pressure Liquid; Cloning, Molecular; Conserved Sequence; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Models, Genetic; Molecular Sequence Data; Molecular Structure; Multigene Family; Oxidation-Reduction; Salicylates; Sequence Alignment; Streptomyces antibioticus	2006
Optimization of heterologous production of the polyketide 6-MSA in Saccharomyces cerevisiae. Biotechnology and bioengineering, 2007, Jul-01, Volume: 97, Issue:4 Topics: Aspergillus nidulans; Bacillus subtilis; Bacterial Proteins; Biomass; Bioreactors; Cell Culture Techniques; Enzyme Activation; Fermentation; Kinetics; Plasmids; Polyketide Synthases; Saccharomyces cerevisiae; Salicylates; Transferases (Other Substituted Phosphate Groups); Transformation, Genetic	2007
Cloning of the pactamycin biosynthetic gene cluster and characterization of a crucial glycosyltransferase prior to a unique cyclopentane ring formation. The Journal of antibiotics, 2007, Volume: 60, Issue:8 Topics: Bacterial Proteins; Cyclopentanes; Genes, Bacterial; Glucosides; Glycosylation; Glycosyltransferases; Multigene Family; Open Reading Frames; Pactamycin; Salicylates; Streptomyces	2007
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification. BMC bioinformatics, 2008, Jan-28, Volume: 9 Topics: Artificial Intelligence; Aspergillus nidulans; Biomarkers; Cluster Analysis; Gene Expression Profiling; Genetic Enhancement; Genotype; Metabolism; Pattern Recognition, Automated; Protein Engineering; Proteomics; Salicylates	2008
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. Metabolic engineering, 2008, Volume: 10, Issue:5 Topics: Acetyl Coenzyme A; Acetyltransferases; Acyltransferases; Aspergillus nidulans; Ligases; Macrolides; Malonyl Coenzyme A; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Elongation Factor 1; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salicylates	2008
Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi. PloS one, 2009, Volume: 4, Issue:2 Topics: Animals; Bacteria; Bacterial Proteins; Evolution, Molecular; Fungal Proteins; Fungi; Gene Duplication; Gene Transfer, Horizontal; Humans; Lichens; Molecular Sequence Data; Molecular Structure; Phylogeny; Polyketide Synthases; Resorcinols; Salicylates; Symbiosis	2009
Insights into bacterial 6-methylsalicylic acid synthase and its engineering to orsellinic acid synthase for spirotetronate generation. Chemistry & biology, 2010, May-28, Volume: 17, Issue:5 Topics: Acyltransferases; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Ligases; Multienzyme Complexes; Oxidation-Reduction; Oxidoreductases; Protein Engineering; Protein Structure, Tertiary; Resorcinols; Salicylates; Streptomyces	2010
Molecular and chemical characterization of the biosynthesis of the 6-MSA-derived meroterpenoid yanuthone D in Aspergillus niger. Chemistry & biology, 2014, Apr-24, Volume: 21, Issue:4 Topics: Acyltransferases; Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Dose-Response Relationship, Drug; Ligases; Microbial Sensitivity Tests; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Salicylates; Small Molecule Libraries; Structure-Activity Relationship; Terpenes	2014
Molecular genetic characterization of terreic acid pathway in Aspergillus terreus. Organic letters, 2014, Oct-17, Volume: 16, Issue:20 Topics: Aspergillus; Biological Products; Biosynthetic Pathways; Molecular Structure; Multigene Family; Quinones; Salicylates	2014
Combining UHPLC-High Resolution MS and Feeding of Stable Isotope Labeled Polyketide Intermediates for Linking Precursors to End Products. Journal of natural products, 2015, Jul-24, Volume: 78, Issue:7 Topics: Algorithms; Aspergillus; Fusarium; Isotope Labeling; Molecular Structure; Patulin; Polyketides; Pyrones; Quinones; Salicylates	2015
Investigation of a 6-MSA Synthase Gene Cluster in Aspergillus aculeatus Reveals 6-MSA-derived Aculinic Acid, Aculins A-B and Epi-Aculin A. Chembiochem : a European journal of chemical biology, 2015, Oct-12, Volume: 16, Issue:15 Topics: Acetates; Acyltransferases; Aspergillus; Ligases; Multienzyme Complexes; Multigene Family; Oxidoreductases; Proline; Pyrones; Salicylates	2015
Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes. Angewandte Chemie (International ed. in English), 2016, Mar-01, Volume: 55, Issue:10 Topics: Chromatography, High Pressure Liquid; Molecular Probes; Salicylates	2016
DIVERSIFY: A Fungal Multispecies Gene Expression Platform. ACS synthetic biology, 2021, 03-19, Volume: 10, Issue:3 Topics: Aspergillus; Cellulose 1,4-beta-Cellobiosidase; CRISPR-Cas Systems; Fungi; Gene Editing; Glucuronidase; RNA, Guide, Kinetoplastida; Salicylates	2021