Page last updated: 2024-09-03

6-methylene-4-pregnene-3,20-dione and dihydrotestosterone

6-methylene-4-pregnene-3,20-dione has been researched along with dihydrotestosterone in 5 studies

Compound Research Comparison

Studies
(6-methylene-4-pregnene-3,20-dione)
Trials
(6-methylene-4-pregnene-3,20-dione)
Recent Studies (post-2010)
(6-methylene-4-pregnene-3,20-dione)
Studies
(dihydrotestosterone)
Trials
(dihydrotestosterone)
Recent Studies (post-2010) (dihydrotestosterone)
20009,3253071,517

Protein Interaction Comparison

ProteinTaxonomy6-methylene-4-pregnene-3,20-dione (IC50)dihydrotestosterone (IC50)
Plasma kallikreinHomo sapiens (human)0.0031
Glucocorticoid receptorHomo sapiens (human)0.54
Sex hormone-binding globulinHomo sapiens (human)0.0038
Progesterone receptorOryctolagus cuniculus (rabbit)0.44
Progesterone receptorHomo sapiens (human)7.3
Mineralocorticoid receptor Homo sapiens (human)0.36
Sex hormone-binding globulinRattus norvegicus (Norway rat)0.023
Androgen receptorHomo sapiens (human)0.0048
Androgen receptorRattus norvegicus (Norway rat)0.4041
Androgen receptorMus musculus (house mouse)0.001
Mineralocorticoid receptorRattus norvegicus (Norway rat)2.1
Testosterone 17-beta-dehydrogenase 3Homo sapiens (human)0.0026

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, LW; Neubauer, BL; Petrow, V; Sikes, RA; Thomsen, S1
Goode, RL; Neubauer, BL; Petrow, V; Toomey, RE1
Collins, RH; Killenberg, PG; Lack, L1
Petrow, V1
Marts, SA; Mukherji, S; Padilla, GM; Petrow, V1

Reviews

1 review(s) available for 6-methylene-4-pregnene-3,20-dione and dihydrotestosterone

ArticleYear
The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications.
    The Prostate, 1986, Volume: 9, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Animals; Dihydrotestosterone; Humans; Male; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Prostate; Prostatic Neoplasms; Rats; Testosterone

1986

Other Studies

4 other study(ies) available for 6-methylene-4-pregnene-3,20-dione and dihydrotestosterone

ArticleYear
Inhibition of experimentally induced mouse prostatic hyperplasia by castration or steroid antagonist administration.
    Biology of reproduction, 1990, Volume: 43, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Azasteroids; Dihydrotestosterone; DNA; Drug Therapy, Combination; Estrogen Antagonists; Female; Male; Mice; Mice, Inbred BALB C; Orchiectomy; Piperidines; Progesterone; Prostatic Hyperplasia; Raloxifene Hydrochloride; Urogenital System

1990
In vivo assay for conversion of testosterone to dihydrotestosterone by rat prostatic steroid 5 alpha-reductase and comparison of two inhibitors.
    The Prostate, 1991, Volume: 19, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Azasteroids; Chromatography, High Pressure Liquid; Dihydrotestosterone; Dose-Response Relationship, Drug; Male; Progesterone; Prostate; Rats; Rats, Inbred F344; Testosterone; Time Factors; Tritium

1991
Rat hepatic bile acid sulfotransferase: enzyme response to androgens and estrogens.
    The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 1

    Topics: Androgens; Animals; Antibodies, Monoclonal; Castration; Chromatography; Chromatography, High Pressure Liquid; Dihydrotestosterone; Epitopes; Estrogens; Ethinyl Estradiol; Female; Immunosorbent Techniques; Liver; Male; Progesterone; Rats; Sulfotransferases; Sulfurtransferases

1987
Endocrine dependence of prostatic cancer upon dihydrotestosterone and not upon testosterone.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:5

    Topics: Adenocarcinoma; Animals; Cells, Cultured; Dihydrotestosterone; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Progesterone; Prostatic Neoplasms; Rats; Testosterone

1984