Page last updated: 2024-09-04

6-methoxyflavone and flavone

6-methoxyflavone has been researched along with flavone in 9 studies

Compound Research Comparison

Studies
(6-methoxyflavone)
Trials
(6-methoxyflavone)
Recent Studies (post-2010)
(6-methoxyflavone)
Studies
(flavone)
Trials
(flavone)
Recent Studies (post-2010) (flavone)
240145661268

Protein Interaction Comparison

ProteinTaxonomy6-methoxyflavone (IC50)flavone (IC50)
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)0.3243
Poly [ADP-ribose] polymerase 1Homo sapiens (human)1.3902
Androgen receptorHomo sapiens (human)5.9
AromataseHomo sapiens (human)6.0027
Dipeptidyl peptidase 4Homo sapiens (human)0.17
Cytochrome P450 1B1Homo sapiens (human)0.6
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)0.144

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS1
Dekermendjian, K; Kahnberg, P; Liljefors, T; Nielsen, M; Sterner, O; Witt, MR1
Komai, K; Morimoto, M; Nakano, A; Nakano, S; Ozaki, T; Tanimoto, K1
Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M1
Haikarainen, T; Joensuu, P; Koivunen, J; Legala, OE; Lehtiö, L; Narwal, M; Obaji, E; Pihlajaniemi, T; Venkannagari, H1
An, JY; Kim, NJ; Kim, SW; Lee, HH; Lee, J; Lee, KT; Park, JS; Shin, JS; Son, SH; Yoo, HS; Yu, J1
Enoch, IVMV; Sameena, Y1

Other Studies

9 other study(ies) available for 6-methoxyflavone and flavone

ArticleYear
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavonoids; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Stomach Diseases; Structure-Activity Relationship

1995
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: Animals; Binding Sites; Brain; Flavonoids; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Reproducibility of Results; Structure-Activity Relationship

1999
Insect antifeedant activity of flavones and chromones against Spodoptera litura.
    Journal of agricultural and food chemistry, 2003, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Chromones; Eating; Flavonoids; Gnaphalium; Insecticides; Methylation; Spodoptera; Structure-Activity Relationship

2003
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:8

    Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2008
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship

2011
Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Animals; Crystallography, X-Ray; Drug Discovery; Flavones; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Isoenzymes; L Cells; Mice; Models, Molecular; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Structure, Tertiary; Tankyrases; Wnt Signaling Pathway

2013
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Flavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Structure-Activity Relationship

2017
Interaction of a flavone loaded on surface-modified dextran-spooled superparamagnetic nanoparticles with β-cyclodextrin and DNA.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:7

    Topics: beta-Cyclodextrins; Dextrans; DNA; Ferric Compounds; Flavones; Magnetite Nanoparticles; Spectrometry, Fluorescence; X-Ray Diffraction

2018