Compounds > 6-methoxyflavone
Page last updated: 2024-09-04

6-methoxyflavone and apigenin

6-methoxyflavone has been researched along with apigenin in 5 studies

Compound Research Comparison

Studies
(6-methoxyflavone)		Trials
(6-methoxyflavone)		Recent Studies (post-2010)
(6-methoxyflavone)		Studies
(apigenin)		Trials
(apigenin)		Recent Studies (post-2010) (apigenin)
240143,273752,086

Protein Interaction Comparison

ProteinTaxonomy6-methoxyflavone (IC50)apigenin (IC50)
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein Kinase Ii Subunit AlphaZea mays1.2
Aldo-keto reductase family 1 member B10Homo sapiens (human)6.6
G2/mitotic-specific cyclin-B2Homo sapiens (human)4
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)3.1311
Estrogen receptorHomo sapiens (human)1.253
Cytochrome P450 1A1Homo sapiens (human)0.427
MyeloperoxidaseHomo sapiens (human)3.8
Cytochrome P450 1A2Homo sapiens (human)0.795
Cyclin-dependent kinase 1Homo sapiens (human)4
Beta-glucuronidaseRattus norvegicus (Norway rat)2.8
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.67
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.02
Androgen receptorHomo sapiens (human)5.2
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.94
AromataseHomo sapiens (human)3.275
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.71
Pyruvate kinase PKMHomo sapiens (human)0.99
G2/mitotic-specific cyclin-B1Homo sapiens (human)4
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.175
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.175
Casein kinase II subunit alpha'Homo sapiens (human)0.85
Amine oxidase [flavin-containing] AHomo sapiens (human)1.398
Amine oxidase [flavin-containing] BHomo sapiens (human)1.12
Dipeptidyl peptidase 4Homo sapiens (human)0.14
Proteasome subunit beta type-5Homo sapiens (human)1.4
Prostaglandin G/H synthase 2Homo sapiens (human)8
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)1.45
Tyrosine-protein kinase SYKHomo sapiens (human)4.2
Xanthine dehydrogenase/oxidaseHomo sapiens (human)1.95
Glycogen synthase kinase-3 alphaHomo sapiens (human)1.4
Glycogen synthase kinase-3 betaHomo sapiens (human)1.4
Mitogen-activated protein kinase 10Homo sapiens (human)2.2
Casein kinase II subunit betaHomo sapiens (human)0.85
Casein kinase II subunit alphaHomo sapiens (human)0.84
Xanthine dehydrogenase/oxidaseBos taurus (cattle)3.57
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)7
Cyclin-dependent kinase 6Homo sapiens (human)2.08
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.06
Cyclin homologHerpesvirus saimiri (strain 11)2.175
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.06
Mitogen-activated protein kinase 14Homo sapiens (human)2.2
Cytochrome P450 1B1Homo sapiens (human)0.1925
Integrase Human immunodeficiency virus 11.5
Casein kinase II subunit alpha 3Homo sapiens (human)0.8
G2/mitotic-specific cyclin-B3Homo sapiens (human)4
Estrogen receptor betaHomo sapiens (human)0.13
Aurora kinase BHomo sapiens (human)3.96
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.175
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)2.9256
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.308
NADPH oxidase 4Homo sapiens (human)1.13
Inositol hexakisphosphate kinase 2Homo sapiens (human)7.1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dekermendjian, K; Kahnberg, P; Liljefors, T; Nielsen, M; Sterner, O; Witt, MR1
Komai, K; Morimoto, M; Nakano, A; Nakano, S; Ozaki, T; Tanimoto, K1
Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M1

Other Studies

5 other study(ies) available for 6-methoxyflavone and apigenin

ArticleYear
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: Animals; Binding Sites; Brain; Flavonoids; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Reproducibility of Results; Structure-Activity Relationship

1999
Insect antifeedant activity of flavones and chromones against Spodoptera litura.
    Journal of agricultural and food chemistry, 2003, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Chromones; Eating; Flavonoids; Gnaphalium; Insecticides; Methylation; Spodoptera; Structure-Activity Relationship

2003
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:8

    Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2008
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship

2011