6-ketoprostaglandin-f1-alpha has been researched along with aluminum-fluoride* in 1 studies
1 other study(ies) available for 6-ketoprostaglandin-f1-alpha and aluminum-fluoride
| Article | Year |
|---|---|
G-proteins and phospholipase activation in endothelial cells.
ATP stimulates arachidonic acid release and prostaglandin biosynthesis (most likely via phospholipase A2 (PLA2) activation) and phospholipase C (PLC) activation in cultured rabbit coronary microvessel endothelial cells. Pertussis toxin pretreatment inhibits ATP stimulated prostaglandin release, but not ATP stimulated phosphatidylinositol turnover. In contrast, activation of G-proteins with GTP tau S or AlF4- stimulates both prostaglandin synthesis and PLC. These observations suggest that PLC activation by ATP involves a G-protein(s) that is not ADP-ribosylated by pertussis toxin and further, that ATP activation of prostaglandin biosynthesis appears to involve a different, pertussis toxin sensitive, G-protein. Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Aluminum; Aluminum Compounds; Animals; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Pertussis Toxin; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Rabbits; Virulence Factors, Bordetella | 1990 |