Page last updated: 2024-09-03

6-iodopenicillanic acid and penicillanic acid

6-iodopenicillanic acid has been researched along with penicillanic acid in 23 studies

Compound Research Comparison

Studies
(6-iodopenicillanic acid)
Trials
(6-iodopenicillanic acid)
Recent Studies (post-2010)
(6-iodopenicillanic acid)
Studies
(penicillanic acid)
Trials
(penicillanic acid)
Recent Studies (post-2010) (penicillanic acid)
23002,764327880

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's8 (34.78)18.2507
2000's1 (4.35)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christensen, H; Martin, MT; Waley, SG1
Alarcón, M; Campos, M; González, H1
Dusart, J; Frère, JM; Jacob, F; Joris, B; Lepage, S1
De Meester, F; Dive, G; Frère, JM; Matagne, A1
De Meester, F; Dehottay, P; Dusart, J; Erpicium, T; Frère, JM; Ghuysen, JM; Joris, B; Klein, D; Lenzini, MV; Van Beeumen, J1
Amicosante, G; Frère, JM; Galleni, M; Joris, B; Oratore, A; Van Beeumen, J1
Frère, JM; Lenzini, MV1
Coyette, J; De Meester, F; Frere, JM; Galleni, M; Joris, B; Reckinger, G; Van Beeumen, J1
Dehottay, P; Duez, C; Dusart, J; Frère, JM; Ghuysen, JM; Kieser, T; Lenzini, MV; Martial, JA1
Cartwright, SJ; De Meester, F; Frère, JM; Lindberg, F; Virden, R; Waley, SG1
Frère, JM; Ghuysen, JM; Jacques, P; Joris, B; Van Beeumen, J1
Bellefroid-Bourguignon, C; De Meester, F; Frère, JM; Joris, B; Reckinger, G; Waley, SG1
Andrews, JM; Patel, N; Wise, R1
Brammer, KW; Moore, BA1
Li, JT; Moosdeen, F; Williams, JD1
Neu, HC1
De Graeve, J; Dormans, C; Duyckaerts, C; Frère, JM1
Frère, JM; Joris, B; Ledent, P; Raquet, X; Van Beeumen, J1
Aplin, RT; Brown, RP; Schofield, CJ1
Di Gleria, K; Halliwell, CM; Hill, HA; Jacob, C1
Basu, D; Basu, J; Narayankumar, DV; Van Beeumen, J1
de Seny, D; Frere, JM; Galleni, M; Laraki, N; Llabres, G; Prosperi-Meys, C; Soto, RP; Valladares, MH1
Amoroso, A; Charlier, P; Dive, G; Fonzé, E; Herman, R; Joris, B; Kerff, F; Luxen, A; Pratt, RF; Sauvage, E; Zervosen, A1

Other Studies

23 other study(ies) available for 6-iodopenicillanic acid and penicillanic acid

ArticleYear
Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.
    The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3

    Topics: Acylation; Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin G; Staphylococcus aureus; Substrate Specificity

1990
Inactivation of beta-lactamase from Shigella flexneri UCSF-129 by 6-beta-iodopenicillanic acid: classification of the enzyme.
    Microbios, 1990, Volume: 63, Issue:254

    Topics: beta-Lactamase Inhibitors; Hydrogen-Ion Concentration; Isoelectric Focusing; Penicillanic Acid; Shigella flexneri

1990
Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis.
    The Biochemical journal, 1990, Oct-15, Volume: 271, Issue:2

    Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; beta-Lactamases; Binding Sites; Chemical Phenomena; Chemistry, Physical; Enzyme Stability; Hot Temperature; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Penicillanic Acid; Serine; Streptomyces; Structure-Activity Relationship; Thermodynamics

1990
Unexpected influence of ionic strength on branched-pathway interactions between beta-lactamases and beta-halogenopenicillanates.
    The Biochemical journal, 1989, Jan-01, Volume: 257, Issue:1

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Kinetics; Osmolar Concentration; Penicillanic Acid

1989
The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.
    The Biochemical journal, 1987, Jun-01, Volume: 244, Issue:2

    Topics: Amino Acid Sequence; beta-Lactamases; Binding Sites; Chromatography, Ion Exchange; Dithionitrobenzoic Acid; Mercaptoethanol; Penicillanic Acid; Peptide Fragments; Spectrophotometry, Ultraviolet; Streptomyces

1987
Chromosome-encoded beta-lactamases of Citrobacter diversus. Interaction with beta-iodopenicillanate and labelling of the active site.
    The Biochemical journal, 1988, Sep-15, Volume: 254, Issue:3

    Topics: Amino Acid Sequence; beta-Lactamase Inhibitors; Binding Sites; Chromosomes, Bacterial; Citrobacter; Isoenzymes; Penicillanic Acid; Peptide Fragments

1988
The beta-lactamase of Streptomyces cacaoi: interaction with cefoxitin and beta-iodopenicillanate.
    Journal of enzyme inhibition, 1985, Volume: 1, Issue:1

    Topics: beta-Lactamase Inhibitors; Cefoxitin; Kinetics; Penicillanic Acid; Streptomyces

1985
The beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanates.
    The Biochemical journal, 1985, May-15, Volume: 228, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; beta-Lactamase Inhibitors; beta-Lactamases; Enterobacter; Enterobacteriaceae; Kinetics; Penicillanic Acid; Spectrophotometry; Tryptophan

1985
Cloning and amplified expression in Streptomyces lividans of a gene encoding extracellular beta-lactamase from Streptomyces albus G.
    Gene, 1986, Volume: 42, Issue:1

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cloning, Molecular; Extracellular Space; Gene Amplification; Genetic Vectors; Penicillanic Acid; Plasmids; Streptomyces

1986
6-beta-Iodopenicillanate as a probe for the classification of beta-lactamases.
    The Biochemical journal, 1986, Nov-01, Volume: 239, Issue:3

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Hydrogen-Ion Concentration; Kinetics; Penicillanic Acid; Spectrophotometry; Thiazines

1986
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 2. Amino acid sequence data.
    European journal of biochemistry, 1987, Feb-02, Volume: 162, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Cyanogen Bromide; Hydrolysis; Kinetics; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Peptide Fragments; Phthalic Acids; Streptomyces; Sulfhydryl Compounds; Trypsin

1987
Automated analysis of enzyme inactivation phenomena. Application to beta-lactamases and DD-peptidases.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactams; Cephaloridine; Enzyme Activation; Hot Temperature; Kinetics; Lactams; Microcomputers; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Signal Processing, Computer-Assisted; Software; Spectrophotometry, Ultraviolet; Zinc

1987
6-beta-bromo- and 6-beta-iodo penicillanic acid, two novel beta-lactamase inhibitors.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:5

    Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Penicillanic Acid

1981
6 beta-Iodopenicillanic acid (UI-38,006), a beta-lactamase inhibitor that extends the antibacterial spectrum of beta-lactam compounds: initial bacteriological characterization.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:3

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Drug Synergism; Female; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance

1981
The effect of inhibitors of beta-lactamases on beta-lactamase extracts and on intact cells.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 9, Issue:4

    Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Cephaloridine; Clavulanic Acid; Hydrolysis; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam

1982
beta-Lactamase inhibitory activity of iodopenicillanate and bromopenicillanate.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1

    Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; Cefazolin; Penicillanic Acid

1983
Interaction of beta-iodopenicillanate with the beta-lactamases of Streptomyces albus G and Actinomadura R39.
    The Biochemical journal, 1982, Dec-01, Volume: 207, Issue:3

    Topics: Actinomycetaceae; beta-Lactamase Inhibitors; Hydrolysis; Kinetics; Mass Spectrometry; Models, Biological; Penicillanic Acid; Streptomyces

1982
A comparative study of class-D beta-lactamases.
    The Biochemical journal, 1993, Jun-01, Volume: 292 ( Pt 2)

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Chromatography, Affinity; Chromatography, Ion Exchange; Cloning, Molecular; Kinetics; Penicillanic Acid; Plasmids; Serine; Substrate Specificity

1993
Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry.
    Biochemistry, 1996, Sep-24, Volume: 35, Issue:38

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Dithiothreitol; Enzyme Inhibitors; Escherichia coli; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Structure; Penicillanic Acid; Serine; Serine Endopeptidases; Trypsin

1996
Site-specific introduction of an electroactive label into a non-electroactive enzyme (beta-lactamase I).
    FEBS letters, 1997, Jan-03, Volume: 400, Issue:2

    Topics: Bacillus cereus; Bacterial Proteins; beta-Lactamase Inhibitors; Binding Sites; Cysteine; Electrochemistry; Enzyme Inhibitors; Ferrous Compounds; Maleimides; Metallocenes; Mutagenesis, Site-Directed; Penicillanic Acid; Penicillinase; Recombinant Fusion Proteins; Substrate Specificity; Sulfhydryl Reagents

1997
Characterization of a beta-lactamase from Mycobacterium smegmatis SN2.
    Biochemistry and molecular biology international, 1997, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Enzyme Inhibitors; Molecular Sequence Data; Mycobacterium; Penicillanic Acid; Sequence Alignment; Substrate Specificity; Sulbactam

1997
Interaction between class B beta-lactamases and suicide substrates of active-site serine beta-lactamases.
    FEBS letters, 1999, Jan-25, Volume: 443, Issue:2

    Topics: beta-Lactamases; Binding Sites; Catalysis; Clavulanic Acid; Isomerism; Penicillanic Acid; Substrate Specificity; Sulbactam; Tazobactam

1999
Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate.
    Journal of the American Chemical Society, 2009, Oct-28, Volume: 131, Issue:42

    Topics: Actinomycetales; Anti-Bacterial Agents; Bacillus subtilis; beta-Lactamase Inhibitors; beta-Lactamases; Crystallography, X-Ray; Enzyme Inhibitors; Models, Molecular; Penicillanic Acid; Penicillin-Binding Proteins; Protein Structure, Tertiary

2009