Page last updated: 2024-08-26

6-hydroxymethylmexiletine and mexiletine

6-hydroxymethylmexiletine has been researched along with mexiletine in 4 studies

*Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties. [MeSH]

*Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties. [MeSH]

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Filipek, M; Paczkowski, D; Podleśny, J1
Gilbert, M; Grech-Bélanger, O; LeBlanc, PP; Turgeon, J1
Coutts, RT; Foster, RT; Freitag, DG; Pasutto, FM1
Coelho, EB; Godoy, AL; Lanchote, VL; Marques, MP; Parisi, CC1

Other Studies

4 other study(ies) available for 6-hydroxymethylmexiletine and mexiletine

ArticleYear
High-performance liquid chromatographic method for the determination of p-hydroxylated and hydroxymethylated metabolites of mexiletine in human serum.
    Journal of chromatography, 1988, Sep-09, Volume: 430, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Mexiletine; Solutions; Spectrophotometry, Ultraviolet

1988
Effect of cigarette smoking on mexiletine kinetics.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:6

    Topics: Adult; Female; Humans; Kinetics; Male; Mexiletine; Propylamines; Smoking; Time Factors

1985
High-performance liquid chromatographic method for resolving the enantiomers of mexiletine and two major metabolites isolated from microbial fermentation media.
    Journal of chromatography, 1993, Jul-02, Volume: 616, Issue:2

    Topics: Chromatography, High Pressure Liquid; Culture Media; Fermentation; Indicators and Reagents; Mexiletine; Mucorales; Stereoisomerism

1993
Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics.
    Chirality, 2009, Volume: 21, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Culture Media; Drugs, Chinese Herbal; Male; Mass Spectrometry; Mexiletine; Rats; Rats, Wistar; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry

2009