Page last updated: 2024-09-03

6-hydroxyethylguanine and guanine

6-hydroxyethylguanine has been researched along with guanine in 5 studies

Compound Research Comparison

Studies
(6-hydroxyethylguanine)
Trials
(6-hydroxyethylguanine)
Recent Studies (post-2010)
(6-hydroxyethylguanine)
Studies
(guanine)
Trials
(guanine)
Recent Studies (post-2010) (guanine)
50016,2788224,809

Protein Interaction Comparison

ProteinTaxonomy6-hydroxyethylguanine (IC50)guanine (IC50)
Purine nucleoside phosphorylaseHomo sapiens (human)5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexander, JA; McCain, DM; Rose, LM; Shealy, YF; Struck, RF1
Ashby, J; Greatbanks, D; Paton, D; Styles, JA; Wright, B1
Kirk, MC; Ludlum, DB; Tong, WP1
Abushamaa, A; Chiu, CS; Giese, RW; Saha, M1
de Zwart, FA; Magnusson, AL; Natarajan, AT; Nilsen, A; Nilsen, OG; Tates, AD; Törnqvist, M; van Dam, FJ; van Sittert, NJ; van Teylingen, CM; Zahlsen, K; Zwinderman, AH1

Other Studies

5 other study(ies) available for 6-hydroxyethylguanine and guanine

ArticleYear
Identification of 7-(2-hydroxyethyl)guanine as a product of alkylation of calf thymus DNA with clomesone.
    Biochemical pharmacology, 1991, Feb-01, Volume: 41, Issue:3

    Topics: Alkylation; Animals; Antineoplastic Agents; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrolysis; Mesylates; Methylation; Thymus Gland

1991
Synthesis of N7-hydroxyethylguanine and O6-hydroxyethylguanine. Markers for the reaction of ethylene oxide (EO) with DNA.
    Mutation research, 1982, Volume: 103, Issue:3-6

    Topics: Chemical Phenomena; Chemistry; DNA; Ethylene Oxide; Guanine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutagens

1982
Molecular pharmacology of the haloethyl nitrosoureas: formation of 6-hydroxyethylguanine in DNA treated with BCNU (N,N1-bis[2-chloroethyl]-N-nitrosourea).
    Biochemical and biophysical research communications, 1981, May-15, Volume: 100, Issue:1

    Topics: Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Indicators and Reagents; Methods; Spectrophotometry, Ultraviolet

1981
Chemical transformation/derivatization of O6-methyl- and O6-(hydroxyethyl)guanine for detection by GC-EC/MS.
    Analytical chemistry, 1993, Nov-01, Volume: 65, Issue:21

    Topics: Chromatography, Thin Layer; DNA; Electrons; Gas Chromatography-Mass Spectrometry; Guanine

1993
Measurement of HPRT mutations in splenic lymphocytes and haemoglobin adducts in erythrocytes of Lewis rats exposed to ethylene oxide.
    Mutation research, 1999, Dec-17, Volume: 431, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Animals; Carcinogens; Chromosome Aberrations; DNA Adducts; Erythrocytes; Ethylene Oxide; Ethylnitrosourea; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Injections, Intraperitoneal; Lymphocytes; Male; Micronucleus Tests; Mutation; Rats; Rats, Inbred Lew; Sister Chromatid Exchange; Spleen

1999