6-hydroxyethylguanine has been researched along with carmustine in 1 studies
*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]
*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]
| Studies (6-hydroxyethylguanine) | Trials (6-hydroxyethylguanine) | Recent Studies (post-2010) (6-hydroxyethylguanine) | Studies (carmustine) | Trials (carmustine) | Recent Studies (post-2010) (carmustine) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 4,168 | 686 | 540 |
| Protein | Taxonomy | 6-hydroxyethylguanine (IC50) | carmustine (IC50) |
|---|---|---|---|
| Glutathione reductase, mitochondrial | Homo sapiens (human) | 8.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kirk, MC; Ludlum, DB; Tong, WP | 1 |
1 other study(ies) available for 6-hydroxyethylguanine and carmustine
| Article | Year |
|---|---|
Molecular pharmacology of the haloethyl nitrosoureas: formation of 6-hydroxyethylguanine in DNA treated with BCNU (N,N1-bis[2-chloroethyl]-N-nitrosourea).
Topics: Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Indicators and Reagents; Methods; Spectrophotometry, Ultraviolet | 1981 |