6-hydroxydopa has been researched along with dihydroxyphenylalanine in 87 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (43.68) | 18.7374 |
| 1990's | 34 (39.08) | 18.2507 |
| 2000's | 5 (5.75) | 29.6817 |
| 2010's | 7 (8.05) | 24.3611 |
| 2020's | 3 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Graham, DG; Jeffs, PW | 1 |
| Byers, L; Ratliff, J; Wick, MM | 1 |
| Kajiyama, H; Nakata, Y; Nomura, Y; Segawa, T | 1 |
| Kostrzewa, RM; McLean, JH; Morgan, DN | 1 |
| Kajiyama, H; Nomura, Y; Segawa, T | 3 |
| Clark, MB; King, JC; Kostrzewa, RM | 1 |
| Nomura, Y; Segawa, T | 3 |
| Naitoh, F; Sakamoto, K; Segawa, T | 1 |
| Dal Toso, R; Facci, L; Leon, A; Moroni, F; Schiavo, N; Skaper, SD; Vantini, G | 1 |
| Aizenman, E; Boeckman, FA; Rosenberg, PA | 1 |
| Acosta, M; Bañón-Arnao, M; García-Cánovas, F; Martinez-Ortiz, F; Rodríguez-López, JN; Tudela, J; Varón, R | 1 |
| Cha, JH; Dure LS, IV; Penney, JB; Sakurai, SY; Young, AB | 1 |
| Aizenman, E; Loring, R; Rosenberg, PA; Xie, Y; Zaleskas, V | 1 |
| Hartmann, C; Klinman, JP | 1 |
| Hoshino, T; Kaneko, H; Ozawa, N; Takahashi, Y; Yamamoto, K | 1 |
| Labruyere, J; Olney, JW; Price, MT; Stewart, GR; Wang, GJ; Zorumski, CF | 1 |
| Aizenman, E; Loring, RH; Rosenberg, PA; White, WF | 1 |
| Burlingame, AL; Janes, SM; Kaur, S; Klinman, JP; Maltby, D; Mu, D; Smith, AJ; Wemmer, D | 1 |
| Dunford, HB; Metodiewa, D | 1 |
| Hansson, C; Rorsman, H; Rosengren, E; Wittbjer, A | 1 |
| Cohen, G; Evans, JM | 1 |
| Chang, JW; Cole, B; Cornwell-Jones, CA; Decker, MW; Goltz, KM; McGaugh, JL; Tran, T | 1 |
| Dunford, HB; Metodiewa, D; Reszka, K | 1 |
| Harston, CT; Klisans-Fuenmayor, D; Kostrzewa, RM | 1 |
| Kostrzewa, RM | 3 |
| Cohen, G; Morrison, ME; Yagi, MJ | 1 |
| Smith, GC; Willis, GL | 1 |
| Agrup, G; Hansson, C; Rorsman, H; Rosengren, E; Tegner, E | 1 |
| Kajiyama, H; Nomura, Y; Obara, K; Segawa, T | 1 |
| Belieu, RM; Chang, HH; Grubbs, RD; Michaelis, EK; Michaelis, ML | 1 |
| Nomura, Y | 1 |
| Pappas, BA; Roberts, DC; Szostak, C; Tombaugh, TN; Vickers, GJ | 1 |
| Bollers, HR; Cornwell-Jones, CA | 1 |
| Demêmes, D; König, N; Serrano, JJ; Szafarczyk, A | 1 |
| Jaim-Etcheverry, G; Zieher, LM | 1 |
| Klisans-Fuenmayor, D; Kostrzewa, RM | 1 |
| Nomura, Y; Oki, K | 1 |
| Bloom, FE; Jaim-Etcheverry, G; Shoemaker, WJ; Zieher, LM | 1 |
| Glasser, RS; Kostrzewa, RM; May, JG; McLean, JH | 1 |
| Clark, MB; Hardin, JC; Harston, CT; Kostrzewa, RM | 1 |
| Eichelman, B; Hegstrand, LR; Kantak, KM | 1 |
| Koob, GF; Le Moal, M; Stinus, L | 1 |
| Huston, JP; Pritzel, M | 1 |
| Fujita, Y; Kawano, T; Maemura, S; Niwa, M; Ozaki, M | 1 |
| Nomura, Y; Oki, K; Segawa, T | 1 |
| Beckmann, H; Deckert, J; Hartmann, J; Heinsen, H; Krause, F; Künig, G; Niedermeyer, B; Ransmayr, G; Riederer, P | 1 |
| Klinman, JP; Plastino, J | 1 |
| Curreli, N; Finazzi-Agró, A; Pedersen, JZ; Porcu, MC; Rescigno, A; Rinaldi, A; Rinaldi, AC; Sanjust, E | 1 |
| Nappi, AJ; Vass, E | 1 |
| Aizenman, E; Newcomer, TA; Rosenberg, PA | 1 |
| Archer, T | 1 |
| Beckmann, H; Deckert, J; Hartmann, J; Heinsen, H; Künig, G; Niedermeyer, B; Ransmayr, G; Riederer, P | 1 |
| Dal Toso, R; Facci, L; Negro, A; Skaper, SD | 1 |
| Chrapusta, SJ; Egan, MF; Karoum, F; Wyatt, RJ | 1 |
| Lin, JY; Mai, LM; Pan, JT | 1 |
| Facci, L; Fadda, E; Manev, H; Skaper, SD | 1 |
| Aizenman, E; Newcomer, TA; Palmer, AM; Rosenberg, PA | 1 |
| Finazzi-Agrò, A; Pedersen, JZ | 1 |
| Hattori, A; Hayashi, K; Kohno, M; Murase, K | 1 |
| Cohen, G; Evans, J | 1 |
| Adams, GW; Burlingame, AL; Mayer, P; Medzihradszky, KF | 1 |
| Bisby, RH; Johnson, SA; Parker, AW; Tavender, SM | 1 |
| Memoli, S; Nappi, AJ; Prota, G; Vass, E | 1 |
| Finazzi Agrò, A; Floris, G; Medda, R; Padiglia, A; Pedersen, JZ; Rotilio, G | 1 |
| Büyükpamukçu, N; Hiçsönmez, A; Oguzkurt, P; Okur, DH; Tanyel, FC | 1 |
| Brus, R; Kostrzewa, RM | 1 |
| Finazzi Agrò, A; Floris, G; Lorrai, A; Medda, R; Murgia, B; Padiglia, A; Pedersen, JZ | 1 |
| Brus, R; Kostrzewa, JP; Kostrzewa, RM | 1 |
| Kannari, K; Matsunaga, M; Shen, H; Suda, T; Yamato, H | 1 |
| Finazzi Agrò, A; Floris, G; Longu, S; Maccioni, P; Medda, R; Mura, A; Padiglia, A; Pedersen, JZ | 1 |
| Borsini, F; Morelli, M; Pinna, A; Pontis, S | 1 |
| Chen, ZW; Datta, S; Dubois, JL; Klinman, JP; Mathews, FS | 1 |
| Alter, H; Domanskyi, A; Gass, P; Geissler, C; Parlato, R; Schober, A; Schütz, G; Vinnikov, IA; Vogt, MA | 1 |
| Ahmad, FJ; Azeem, A; Iqbal, Z; Khar, RK; Negi, LM; Talegaonkar, S | 1 |
| Andrake, M; Chandramouly, G; Glickman, JF; Kent, T; Luz, A; McDevitt, S; Pomerantz, RT; Skorski, T; Sullivan, K | 1 |
| Deng, ZK; Wu, J; Zhao, YM | 1 |
| Berta, B; Gálosi, R; Kállai, V; Kovács, A; Lénárd, L; Ollmann, T; Péczely, L; Petykó, Z; Tóth, A | 1 |
| Guo, D; Liu, H; Liu, J; Liu, Y; Wang, J; Zhao, Z | 1 |
| Agostinho, P; Aguiar, AS; Cunha, RA; Ferreira, SG; Prediger, RD; Silva, HB; Speck, AE; Tomé, ÂR | 1 |
| Guo, Q; Liu, Z; Smith, WW; Wang, B; Wang, X; Zhu, Y | 1 |
7 review(s) available for 6-hydroxydopa and dihydroxyphenylalanine
| Article | Year |
|---|---|
6-Hydroxydopa: the redox cofactor in plasma amine oxidase.
Topics: Animals; Coenzymes; Dihydroxyphenylalanine; Molecular Structure; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; PQQ Cofactor; Quinolones | 1991 |
Reorganization of noradrenergic neuronal systems following neonatal chemical and surgical injury.
Topics: Adrenergic Fibers; Animals; Benzylamines; Brain; Dihydroxyphenylalanine; Guanethidine; Hydroxydopamines; Mice; Neurotoxins; Norepinephrine; Oxidopamine; Rats | 1988 |
Amine accumulation in behavioural pathology.
Topics: Animals; Behavior, Animal; Brain; Catecholamines; Cats; Colchicine; Consummatory Behavior; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine beta-Hydroxylase; Histocytochemistry; Hydroxydopamines; Hypothalamic Area, Lateral; Hypothalamus; Kainic Acid; Medial Forebrain Bundle; Neural Pathways; Oxidopamine; Peripheral Nerves; Rats; Receptors, Dopamine; Serotonin; Substantia Nigra | 1985 |
Protein-radical enzymes.
Topics: Dihydroxyphenylalanine; Enzymes; Free Radicals; Glycine; Molecular Structure; PQQ Cofactor; Quinolones; Tryptophan; Tyrosine | 1993 |
Destruction of catecholamine-containing neurons by 6-hydroxydopa, an endogenous amine oxidase cofactor.
Topics: Amine Oxidase (Copper-Containing); Animals; Catecholamines; Dihydroxyphenylalanine; Humans; Neurons; Oxidoreductases Acting on CH-NH Group Donors | 1998 |
Evolution of neurotoxins: from research modalities to clinical realities.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Animals; Benzylamines; Botulinum Toxins, Type A; Dihydroxyphenylalanine; Dihydroxytryptamines; Glutamic Acid; Humans; Models, Animal; Nerve Growth Factor; Neurosciences; Neurotoxins; Oxidopamine; Terminology as Topic | 2009 |
Perinatal Lesioning and Lifelong Effects of the Noradrenergic Neurotoxin 6-Hydroxydopa.
Topics: Animals; Brain; Brain Mapping; Dihydroxyphenylalanine; Neurons; Neurotoxins | 2016 |
80 other study(ies) available for 6-hydroxydopa and dihydroxyphenylalanine
| Article | Year |
|---|---|
The role of 2,4,5-trihydroxyphenylalanine in melanin biosynthesis.
Topics: Basidiomycota; Dihydroxyphenylalanine; Kinetics; Melanins; Monophenol Monooxygenase; Oxidation-Reduction; Periodic Acid; Spectrophotometry; Spectrophotometry, Ultraviolet | 1977 |
Selective toxicity of 6-hydroxydopa for melanoma cells.
Topics: Animals; Cells, Cultured; Cricetinae; Dihydroxyphenylalanine; Growth Inhibitors; Melanoma; Mice; Neoplasms, Experimental | 1979 |
Muscarinic cholinergic binding in striatal and mesolimbic areas of the rat: reduction by 6-hydroxydopa.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dihydroxyphenylalanine; Female; Limbic System; Male; Pilocarpine; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1979 |
Effects of 6-hydroxydopamine and 6-hydroxydopa on development of behavior.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Dihydroxyphenylalanine; Exploratory Behavior; Hydroxydopamines; Motor Activity; Norepinephrine; Rats | 1979 |
Decrease in muscarinic cholinergic response of the rat heart following treatment with 6-hydroxydopa.
Topics: Acetylcholine; Animals; Dihydroxyphenylalanine; Female; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1979 |
Loss of nerve cell bodies in caudal locus coeruleus following treatment of neonates with 6-hydroxydopa.
Topics: Animals; Animals, Newborn; Cell Count; Dihydroxyphenylalanine; Locus Coeruleus; Rats | 1979 |
Striatal dopamine content reduced in developing rats treated with 6-hydroxydopa.
Topics: Age Factors; Animals; Corpus Striatum; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Female; Male; Rats | 1979 |
Muscarinic hyposensitivity in the developing rat pretreated with 6-hydroxydopa.
Topics: Animals; Atropine; Catalepsy; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Motor Activity; Parasympathetic Nervous System; Pilocarpine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1978 |
Effects of 6-hydroxydopa and 5,6-dihydroxytryptophan treatment on spontaneous motor activity and brain monoamines in mice.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Male; Mice; Motor Activity; Norepinephrine | 1975 |
Characterization of 2,4,5-trihydroxyphenylalanine neurotoxicity in vitro and protective effects of ganglioside GM1: implications for Parkinson's disease.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebellum; Dihydroxyphenylalanine; G(M1) Ganglioside; Mesencephalon; MPTP Poisoning; Oxidation-Reduction; Parkinson Disease; Quinoxalines; Rats; Rats, Sprague-Dawley | 1992 |
Glutathione prevents 2,4,5-trihydroxyphenylalanine excitotoxicity by maintaining it in a reduced, non-active form.
Topics: Animals; Cerebral Cortex; Dihydroxyphenylalanine; Electrophysiology; Glutathione; Neurons; Oxidation-Reduction; Rats | 1992 |
Catalytic oxidation of 2,4,5-trihydroxyphenylalanine by tyrosinase: identification and evolution of intermediates.
Topics: Animals; Dihydroxyphenylalanine; Kinetics; Monophenol Monooxygenase; Oxidation-Reduction; Substrate Specificity | 1992 |
2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Corpus Striatum; Dihydroxyphenylalanine; Ibotenic Acid; Kainic Acid; Kinetics; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Tritium | 1991 |
2,4,5-trihydroxyphenylalanine in solution forms a non-N-methyl-D-aspartate glutamatergic agonist and neurotoxin.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Chickens; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Eye; In Vitro Techniques; Neurons; Neurotoxins; Ocular Physiological Phenomena; Quinoxalines; Rats | 1991 |
Structure-function studies of substrate oxidation by bovine serum amine oxidase: relationship to cofactor structure and mechanism.
Topics: Amine Oxidase (Copper-Containing); Benzylamines; Binding Sites; Deuterium; Dihydroxyphenylalanine; Hydrolysis; Kinetics; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; PQQ Cofactor; Quinolones; Structure-Activity Relationship; Substrate Specificity | 1991 |
Skin conductance activity after intraventricular administration of 6-hydroxydopa in rats.
Topics: Animals; Arousal; Brain; Dihydroxyphenylalanine; Dopamine; Galvanic Skin Response; Habituation, Psychophysiologic; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chick Embryo; Dibenzocycloheptenes; Dihydroxyphenylalanine; Dizocilpine Maleate; Hippocampus; Huntington Disease; Levodopa; Neurons; Parkinson Disease; Quinoxalines; Receptors, Neurotransmitter; Retina | 1990 |
A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dihydroxyphenylalanine; Evoked Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats | 1990 |
A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Amino Acid Sequence; Animals; Binding Sites; Cattle; Copper; Dihydroxyphenylalanine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Peptide Fragments; Quinones; Spectrophotometry, Ultraviolet | 1990 |
The role of myeloperoxidase in the oxidation of biologically active polyhydroxyphenols (substituted catechols).
Topics: Animals; Catalysis; Catecholamines; Catechols; Dihydroxyphenylalanine; Dogs; Electron Spin Resonance Spectroscopy; Norepinephrine; Oxidation-Reduction; Peroxidase; Spectrophotometry; Spin Labels; Substrate Specificity; Superoxide Dismutase | 1990 |
Production of 6-hydroxydopa by human tyrosinase.
Topics: Catalysis; Catechol Oxidase; Cell Line; Culture Media; Dihydroxyphenylalanine; Humans; Melanoma; Monophenol Monooxygenase | 1985 |
Studies on the formation of 6-hydroxydopamine in mouse brain after administration of 2,4,5-trihydroxyphenylalanine (6-hydroxyDOPA).
Topics: Animals; Brain; Carbidopa; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Hydroxydopamines; Male; Mice; Norepinephrine; Oxidopamine; Pargyline; Reserpine; Synaptic Vesicles | 1989 |
Neonatal 6-hydroxydopa, but not DSP-4, elevates brainstem monoamines and impairs inhibitory avoidance learning in developing rats.
Topics: Animals; Animals, Newborn; Avoidance Learning; Benzylamines; Biogenic Monoamines; Brain Stem; Dihydroxyphenylalanine; Male; Memory; Neurotoxins; Rats; Rats, Inbred Strains; Retention, Psychology | 1989 |
Oxidation of the substituted catechols dihydroxyphenylalanine methyl ester and trihydroxyphenylalanine by lactoperoxidase and its compounds.
Topics: Catechol Oxidase; Catechols; Dihydroxyphenylalanine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Indolequinones; Indoles; Lactoperoxidase; Oxidation-Reduction; Peroxidases; Quinones | 1989 |
Alterations in noradrenergic innervation of the brain following dorsal bundle lesions in neonatal rats.
Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Cerebellum; Dihydroxyphenylalanine; Locus Coeruleus; Medulla Oblongata; Nerve Crush; Nerve Fibers; Nerve Regeneration; Norepinephrine; Pons; Rats | 1986 |
In vitro studies of 2,4-dihydroxyphenylalanine, a prodrug targeted against malignant melanoma cells.
Topics: Animals; Cell Survival; Cells, Cultured; Dihydroxyphenylalanine; Leukemia L1210; Mammary Neoplasms, Experimental; Melanoma; Mice; Monophenol Monooxygenase | 1985 |
Methaemoglobin-catalysed formation of dopa and 6-OH-dopa from tyrosine.
Topics: Animals; Cattle; Choroid; Dihydroxyphenylalanine; In Vitro Techniques; Methemoglobin; Pigment Epithelium of Eye; Tyrosine | 1983 |
Hypersensitivity of cardiac beta-adrenergic receptors after neonatal treatment of rats with 6-hydroxydopa.
Topics: Animals; Animals, Newborn; Binding Sites; Dihydroalprenolol; Dihydroxyphenylalanine; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepinephrine; Ornithine Decarboxylase; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
The increase of cardiac beta 1-subtype of beta-adrenergic receptors in adult rats following neonatal 6-hydroxydopa treatment.
Topics: Animals; Animals, Newborn; Computers; Dihydroalprenolol; Dihydroxyphenylalanine; Female; Heart; Kinetics; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1982 |
Differential effects of metal ligands on synaptic membrane glutamate binding and uptake systems.
Topics: Animals; Azides; Biological Transport; Brain; Dihydroxyphenylalanine; Glutamates; Kinetics; Ligands; Phenanthrolines; Potassium Cyanide; Rats; Receptors, Cell Surface; Receptors, Glutamate; Sodium Azide; Synaptic Membranes | 1982 |
Possible influence of noradrenaline on beta-adrenergic and muscarinic cholinergic receptors in rat heart: effects of 6-hydroxydopa, isoproterenol, and desmethylimipramine.
Topics: Animals; Desipramine; Dihydroalprenolol; Dihydroxyphenylalanine; Female; Heart; Isoproterenol; Male; Myocardium; Norepinephrine; Ornithine Decarboxylase; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Muscarinic | 1983 |
Influence of neonatal treatment with 6-hydroxydopa on clonidine-induced locomotor stimulation in the infant rat.
Topics: Animals; Animals, Newborn; Clonidine; Dihydroxyphenylalanine; Female; Male; Motor Activity; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1983 |
Failure to replicate the dorsal bundle extinction effect: telencephalic norepinephrine depletion does not reliably increase resistance to extinction but does augment gustatory neophobia.
Topics: Afferent Pathways; Animals; Brain Mapping; Conditioning, Operant; Dihydroxyphenylalanine; Extinction, Psychological; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Taste; Telencephalon | 1983 |
Neonatal 6-hydroxydopa alters conspecific odor investigation by male rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Female; Gerbillinae; Male; Myocardium; Norepinephrine; Odorants; Rats; Rats, Inbred Strains; Smell | 1983 |
Role of catecholamines in nervous system development: effects of prenatal 6-hydroxydopa treatment on behaviour and brain structures.
Topics: Animals; Behavior, Animal; Brain; Catecholamines; Cerebellar Cortex; Dihydroxyphenylalanine; Female; Male; Motor Activity; Parietal Lobe; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Sex Characteristics | 1983 |
Neurotoxins and developing monoaminergic neurons.
Topics: Adrenergic Fibers; Amines; Animals; Animals, Newborn; Benzylamines; Blood-Brain Barrier; Dihydroxyphenylalanine; Hydroxydopamines; Nervous System; Oxidopamine; Rats | 1983 |
Development of an opioid-specific action of morphine in modifying recovery of neonatally-damaged noradrenergic fibers in rat brain.
Topics: Adrenergic Fibers; Animals; Animals, Newborn; Brain; Brain Chemistry; Dihydroxyphenylalanine; Endorphins; Morphine; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains | 1984 |
Developmental change in rearing response to atropine in rats treated with 6-hydroxydopa.
Topics: Age Factors; Animals; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Drug Synergism; Female; Male; Rats | 1980 |
TRH-induced behavioral arousal in developing rats pretreated with 6-hydroxydopa.
Topics: Aging; Animals; Animals, Newborn; Catecholamines; Dihydroxyphenylalanine; Drug Interactions; Female; Flupenthixol; Male; Motor Activity; Phenoxybenzamine; Rats; Thyrotropin-Releasing Hormone; Time Factors | 1980 |
Antiserum to nerve growth factor does not prevent the increase of brain stem noradrenaline after neonatal 6-hydroxydopa.
Topics: Animals; Animals, Newborn; Brain; Brain Stem; Dihydroxyphenylalanine; Female; Immune Sera; Male; Microscopy, Fluorescence; Nerve Growth Factors; Nerve Regeneration; Norepinephrine; Rats | 1980 |
Effects of neonatal 6-hydroxydopa on behavior in female rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Dihydroxyphenylalanine; Female; Habituation, Psychophysiologic; Motor Activity; Norepinephrine; Postural Balance; Rats; Sexual Behavior, Animal | 1980 |
Opiate-enhanced toxicity and noradrenergic sprouting in rats treated with 6-hydroxydopa.
Topics: Animals; Animals, Newborn; Brain Chemistry; Cerebral Cortex; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Synergism; Endorphins; Morphine; Naloxone; Narcotics; Neurons; Norepinephrine; Rats | 1981 |
Facilitation of shock-induced fighting following intraventricular 5,7-dihydroxytryptamine and 6-hydroxydopa.
Topics: 5,7-Dihydroxytryptamine; Aggression; Analgesics; Animals; Biogenic Amines; Brain Chemistry; Dihydroxyphenylalanine; Dihydroxytryptamines; Electroshock; Humans; Injections, Intraventricular; Male; Rats; Stimulation, Chemical | 1981 |
Hyperactivity and hypoactivity produced by lesions to the mesolimbic dopamine system.
Topics: Animals; Apomorphine; Brain Mapping; Dihydroxyphenylalanine; Dopamine; Limbic System; Male; Motor Activity; Nucleus Accumbens; Radio Waves; Rats; Tegmentum Mesencephali | 1981 |
Neural and behavioral plasticity: crossed nigro-thalamic projections following unilateral substantia nigra lesions.
Topics: Animals; Brain Mapping; Dihydroxyphenylalanine; Kainic Acid; Motor Activity; Neural Pathways; Rats; Substantia Nigra; Thalamus | 1981 |
[Alpha-methyldopa and brain monoamines].
Topics: Animals; Antihypertensive Agents; Biotransformation; Brain; Catecholamines; Dihydroxyphenylalanine; Female; Gestational Age; Hypertension; Male; Methyldopa; Neurons; Nordefrin; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Sympathectomy, Chemical | 1982 |
Involvement of central noradrenergic system in thyrotropin-releasing hormone-induced behavioral excitement in 6-OHDOPA-treated, infant rats.
Topics: Animals; Behavior, Animal; Desipramine; Dihydroxyphenylalanine; Dopamine; Female; Male; Norepinephrine; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone; Time Factors | 1982 |
Interactions of neurotoxins with non-NMDA glutamate receptors: an autoradiographic study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Autoradiography; beta-Alanine; Binding, Competitive; Dihydroxyphenylalanine; Hippocampus; Humans; Kainic Acid; Neurotoxins; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1994 |
Limited proteolysis of Hansenula polymorpha yeast amine oxidase: isolation of a C-terminal fragment containing both a copper and quino-cofactor.
Topics: Amine Oxidase (Copper-Containing); Coenzymes; Copper; Dihydroxyphenylalanine; Histidine; Oxidoreductases Acting on CH-NH Group Donors; Pichia; Serine Endopeptidases | 1995 |
Autoxidation of 4-methylcatechol: a model for the study of the biosynthesis of copper amine oxidases quinonoid cofactor.
Topics: Amine Oxidase (Copper-Containing); Amino Acid Sequence; Catechols; Chelating Agents; Copper; Cyclic N-Oxides; Dihydroxyphenylalanine; Dipeptides; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Oligopeptides; Oxidation-Reduction; Oxygen; Spectrophotometry; Spin Labels; Structure-Activity Relationship | 1995 |
The effects of glutathione and ascorbic acid on the oxidations of 6-hydroxydopa and 6-hydroxydopamine.
Topics: Antioxidants; Ascorbic Acid; Dihydroxyphenylalanine; Glutathione; Models, Chemical; Oxidation-Reduction; Oxidopamine | 1994 |
Iron-mediated oxidation of 3,4-dihydroxyphenylalanine to an excitotoxin.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ascorbic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Electrophysiology; Hydrogen Peroxide; Iron; Neurons; Neurotoxins; Oxidation-Reduction; Rats | 1995 |
Behavioural retardation in the neuropathology of mental retardation.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dihydroxyphenylalanine; Dopamine Agents; Female; Haloperidol; Intellectual Disability; Learning; Male; Mercury Poisoning; Methylazoxymethanol Acetate; Metoclopramide; Mice; Motor Activity; Organotin Compounds; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Excitotoxins L-beta-oxalyl-amino-alanine (L-BOAA) and 3,4,6-trihydroxyphenylalanine (6-OH-DOPA) inhibit [3H] alpha-amino-3- hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) binding in human hippocampus.
Topics: Aged; Aged, 80 and over; Amino Acids, Diamino; Autoradiography; beta-Alanine; Binding, Competitive; Dihydroxyphenylalanine; Glutamates; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Pyramidal Cells; Receptors, AMPA | 1994 |
Brain-derived neurotrophic factor selectively rescues mesencephalic dopaminergic neurons from 2,4,5-trihydroxyphenylalanine-induced injury.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Dihydroxyphenylalanine; Dopamine; Female; G(M1) Ganglioside; gamma-Aminobutyric Acid; Mesencephalon; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Pregnancy; Rats; Recombinant Proteins; Tyrosine 3-Monooxygenase | 1993 |
Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study.
Topics: Animals; Brain; Carbidopa; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Drug Combinations; Drug Stability; Frontal Lobe; Gas Chromatography-Mass Spectrometry; Injections, Intraventricular; Male; Oxidopamine; Pargyline; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1993 |
Effects of systemic administration of 6-hydroxydopamine, 6-hydroxydopa and 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on tuberoinfundibular dopaminergic neurons in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Arcuate Nucleus of Hypothalamus; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Neurons; Oxidopamine; Rats | 1993 |
A semisynthetic glycosphingolipid (LIGA20) reduces 2,4, 5-trihydroxyphenylalanine neurotoxicity in primary neuronal cultures.
Topics: Animals; Cells, Cultured; Cerebellum; Dihydroxyphenylalanine; G(M1) Ganglioside; Glycosphingolipids; Neurons; Parkinson Disease; Rats; Sphingosine | 1993 |
Nonenzymatic conversion of 3,4-dihydroxyphenylalanine to 2,4,5-trihydroxyphenylalanine and 2,4,5-trihydroxyphenylalanine quinone in physiological solutions.
Topics: Buffers; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Norepinephrine; Oxidation-Reduction; Solutions | 1993 |
Stimulation of nerve growth factor synthesis/secretion in mouse astroglial cells by coenzymes.
Topics: 3T3 Cells; Animals; Astrocytes; Cell Survival; Cells, Cultured; Coenzymes; Dihydroxyphenylalanine; Mice; Mice, Inbred BALB C; Nerve Growth Factors; Oxidation-Reduction; PQQ Cofactor; Quinolones; Thioctic Acid | 1993 |
Catecholamine uptake inhibitors elevate 6-hydroxydopamine in brain after administration of 6-hydroxydopa.
Topics: Animals; Axons; Brain; Catecholamines; Cerebral Cortex; Chromatography, High Pressure Liquid; Desipramine; Dihydroxyphenylalanine; Membranes; Mice; Nerve Endings; Neurons; Nomifensine; Oxidopamine | 1993 |
Mass spectrometric studies of the primary sequence and structure of bovine liver and serum amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Cloning, Molecular; Coenzymes; Dihydroxyphenylalanine; Liver; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Oxidoreductases Acting on CH-NH Group Donors; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Spectrometry, Mass, Fast Atom Bombardment; Spectrometry, Mass, Secondary Ion; Trypsin | 1995 |
The free radical site in pea seedling copper amine oxidase probed by resonance Raman spectroscopy and generated by photolysis of caged substrate.
Topics: Amine Oxidase (Copper-Containing); Benzaldehydes; Benzylamines; Dihydroxyphenylalanine; Free Radicals; Phenethylamines; Photolysis; Pisum sativum; Spectrum Analysis, Raman; Spermidine | 1996 |
The effects of hydroxyl radical attack on dopa, dopamine, 6-hydroxydopa, and 6-hydroxydopamine.
Topics: Benzoquinones; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Hydroxyl Radical; Melanins; Models, Chemical; Oxidation-Reduction; Oxidopamine; Quinones | 1995 |
The reaction mechanism of copper amine oxidase: detection of intermediates by the use of substrates and inhibitors.
Topics: Aerobiosis; Amine Oxidase (Copper-Containing); Anaerobiosis; Aniline Compounds; Apoenzymes; Benzylamines; Coenzymes; Copper; Dihydroxyphenylalanine; Electron Spin Resonance Spectroscopy; Fabaceae; Metalloproteins; Plants, Medicinal; Putrescine; Semicarbazides; Spectrophotometry; Substrate Specificity | 1995 |
The effects of vasodilatation and chemical sympathectomy on spermatogenesis after unilateral testicular torsion: a flow cytometric DNA analysis.
Topics: Animals; Dihydroxyphenylalanine; DNA; Flow Cytometry; Haploidy; Male; Pentoxifylline; Rats; Spermatic Cord Torsion; Spermatogenesis; Sympathectomy, Chemical; Testicular Diseases; Vasodilation; Vasodilator Agents; Verapamil | 1998 |
Effect of metal substitution in copper amine oxidase from lentil seedlings.
Topics: Amine Oxidase (Copper-Containing); Benzylamines; Copper; Dihydroxyphenylalanine; Fabaceae; Hydrazines; Kynuramine; Metals; Oxidation-Reduction; Plants; Plants, Medicinal; Substrate Specificity; Zinc | 1999 |
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum.
Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Denervation; Dihydroxyphenylalanine; Dopamine; Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Neostriatum; Pregnancy; Rats; Salicylic Acid; Serotonin | 2000 |
Fluoxetine reduces L-DOPA-derived extracellular DA in the 6-OHDA-lesioned rat striatum.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Extracellular Space; Fluoxetine; Levodopa; Male; Parkinson Disease; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors | 2001 |
Nitric oxide covalently labels a 6-hydroxydopa-derived free radical intermediate in the catalytic cycle of copper/quinone-containing amine oxidase from lentil seedlings.
Topics: Amine Oxidase (Copper-Containing); Benzoquinones; Catalysis; Copper; Dihydroxyphenylalanine; Free Radicals; Lens Plant; Molecular Structure; Nitric Oxide; Oxidation-Reduction; Seedlings; Time Factors | 2005 |
Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Dihydroxyphenylalanine; Dopamine Agents; Functional Laterality; Immunohistochemistry; Levodopa; Male; Neuroprotective Agents; Parkinson Disease; Psychomotor Performance; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles; Tyrosine 3-Monooxygenase; Vibrissae | 2007 |
Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Topics: Amine Oxidase (Copper-Containing); Binding Sites; Copper; Dihydroxyphenylalanine; Mutation; Oxidation-Reduction; Oxygenases; Pichia; Tyrosine | 2010 |
Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopamine Agents; Gene Deletion; Gene Expression Regulation; Mice; Mice, Knockout; Neurons; Parkinson Disease; Pol1 Transcription Initiation Complex Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; TOR Serine-Threonine Kinases; Tyrosine 3-Monooxygenase | 2011 |
Oil based nanocarrier system for transdermal delivery of ropinirole: a mechanistic, pharmacokinetic and biochemical investigation.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiparkinson Agents; Biological Availability; Brain; Calorimetry, Differential Scanning; Catalase; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dihydroxyphenylalanine; Disease Models, Animal; Drug Carriers; Drug Compounding; Emulsions; Gels; Glutathione; Indoles; Male; Nanoparticles; Nanotechnology; Oils; Parkinsonian Disorders; Rats; Rats, Wistar; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; Thiobarbituric Acid Reactive Substances | 2012 |
Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.
Topics: Allosteric Regulation; Apoptosis; BRCA1 Protein; BRCA2 Protein; Cell Line; Cell Proliferation; Dihydroxyphenylalanine; DNA Damage; DNA, Single-Stranded; Electrophoretic Mobility Shift Assay; Humans; Inhibitory Concentration 50; Microscopy, Fluorescence; Neoplasms; Protein Binding; Rad52 DNA Repair and Recombination Protein; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Small Molecule Libraries | 2015 |
Neuroprotective action and mechanistic evaluation of protodioscin against rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Brain; Cell Line, Tumor; Cognition; Dihydroxyphenylalanine; Diosgenin; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Humans; Male; Maze Learning; Neuroprotective Agents; NF-E2-Related Factor 2; Parkinsonian Disorders; Rats, Wistar; Saponins | 2018 |
Destruction of noradrenergic terminals increases dopamine concentration and reduces dopamine metabolism in the medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Dihydroxyphenylalanine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Male; Neural Pathways; Neurons; Norepinephrine; Oxidopamine; Piperazines; Prefrontal Cortex; Rats, Wistar; Yohimbine | 2018 |
Regulation of Actg1 and Gsta2 is possible mechanism by which capsaicin alleviates apoptosis in cell model of 6-OHDA-induced Parkinson's disease.
Topics: Actins; Animals; Antiparkinson Agents; Apoptosis; Capsaicin; Cell Line, Tumor; Dihydroxyphenylalanine; Disease Models, Animal; Gene Expression Regulation; Glutathione Transferase; Humans; Isoenzymes; Neurons; Parkinson Disease; Rats; Signal Transduction; Substantia Nigra | 2020 |
Exercise decreases aberrant corticostriatal plasticity in an animal model of l-DOPA-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Benserazide; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dyskinesia, Drug-Induced; Exercise Therapy; Levodopa; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Parkinsonian Disorders; Running; Time Factors | 2021 |
Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.
Topics: Adenine; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Astrocytes; Autophagy; Behavior, Animal; Dihydroxyphenylalanine; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Male; Motor Activity; Nerve Degeneration; NF-E2-Related Factor 2; Oleanolic Acid; Parkinsonian Disorders; Phenotype; Rats, Sprague-Dawley; Repressor Proteins; Rotenone; Signal Transduction; Sirolimus | 2021 |