6-hydroxychlorzoxazone and dextromethorphan

6-hydroxychlorzoxazone has been researched along with dextromethorphan in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fisher, JM; Gardner, MJ; Kolluri, S; Moller, RA; Obach, RS; Taylor, AE; Walsky, RL	1
Mehvar, R; Vuppugalla, R	1
Aboagye, EO; Clarke, S; Edwards, RJ; Lee, P; Liddle, C; Lozan-Kuehne, JP; Maslen, L; Ramaswami, R; Sharma, R; Trousil, S	1

Trials

2 trial(s) available for 6-hydroxychlorzoxazone and dextromethorphan

Article	Year
Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism. The Annals of pharmacotherapy, 2006, Volume: 40, Issue:1 Topics: Administration, Oral; Chlorzoxazone; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dextromethorphan; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Dyspepsia; Female; Humans; Inpatients; Metabolic Clearance Rate; Middle Aged; Postmenopause; Pyrrolidines; Retrospective Studies; Tetrahydronaphthalenes; Time Factors	2006
Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation. British journal of pharmacology, 2019, Volume: 176, Issue:18 Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Cytokines; Dextromethorphan; Female; Humans; Inflammation; Middle Aged; Omeprazole; Ovarian Neoplasms	2019

Article

Year

Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism.

The Annals of pharmacotherapy, 2006, Volume: 40, Issue:1

Topics: Administration, Oral; Chlorzoxazone; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dextromethorphan; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Dyspepsia; Female; Humans; Inpatients; Metabolic Clearance Rate; Middle Aged; Postmenopause; Pyrrolidines; Retrospective Studies; Tetrahydronaphthalenes; Time Factors

2006

Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation.

British journal of pharmacology, 2019, Volume: 176, Issue:18

Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Cytokines; Dextromethorphan; Female; Humans; Inflammation; Middle Aged; Omeprazole; Ovarian Neoplasms

2019

Other Studies

1 other study(ies) available for 6-hydroxychlorzoxazone and dextromethorphan

Article	Year
Selective effects of nitric oxide on the disposition of chlorzoxazone and dextromethorphan in isolated perfused rat livers. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7 Topics: Alcohol Oxidoreductases; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P450 Family 2; Dextromethorphan; Dextrorphan; Enzyme Inhibitors; Glucuronosyltransferase; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Liver; Male; Nitric Oxide Donors; Nitroprusside; Perfusion; Rats; Rats, Sprague-Dawley; Umbelliferones	2006

Article

Year

Selective effects of nitric oxide on the disposition of chlorzoxazone and dextromethorphan in isolated perfused rat livers.

Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

Topics: Alcohol Oxidoreductases; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P450 Family 2; Dextromethorphan; Dextrorphan; Enzyme Inhibitors; Glucuronosyltransferase; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Liver; Male; Nitric Oxide Donors; Nitroprusside; Perfusion; Rats; Rats, Sprague-Dawley; Umbelliferones

2006