6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with melatonin in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 23 (58.97) | 29.6817 |
| 2010's | 13 (33.33) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bouissac, J; Coowar, D; Hanbali, M; Luu, B; Mohier, E; Paschaki, M | 1 |
| Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Juskova, M; Milackova, I; Snirc, V; Stefek, M; Triantos, N; Tsantili-Kakoulidou, A | 1 |
| Brogi, S; Butini, S; Campiani, G; Esteban, G; Inokuchi, T; Marco-Contelles, J; Shionoya, M; Unzeta, M; Wang, L; Wu, MY | 1 |
| Kong, LY; Li, F; Li, XM; Wang, J; Wang, XB; Wang, ZM; Wu, JJ | 1 |
| Cai, P; Kong, LY; Li, F; Liu, QH; Wang, J; Wang, XB; Wu, JJ; Yang, XL | 1 |
| Cai, P; Kong, LY; Li, F; Wang, J; Wang, XB; Wu, JJ; Yang, XL | 1 |
| Feng, F; He, S; Jiang, H; Jiang, X; Liu, W; Qu, W; Sun, H; Zhou, J | 1 |
| Kumar, S; Mishra, S; Modi, G; Rai, H; Singh, G; Singh, GK; Singh, YP; Srikrishna, S | 1 |
| Longoni, B; Marchiafava, P; Pryor, WA | 1 |
| Ross, A; Stolc, S; Vlkolinský, R | 1 |
| Ho, LT; Lin, AM | 1 |
| Acuña-Castroviejo, D; Escames, G; León, J; Macías, M; Martín, M | 1 |
| Acuña-Castroviejo, D; Escames, G; Khaldy, H; León, J; Luna, JD; Vives, F | 1 |
| Acuña-Castroviejo, D; Allué, JL; García, JJ; Martínez-Ballarín, E; Osuna, C; Reiter, RJ; Robinson, M | 1 |
| Bachratá, K; Horáková, L; Ondrejicková, O; Vajdová, M | 1 |
| Elsner, P; Fischer, TW | 1 |
| Carrupt, P; Salvi, A; Testa, B; Tillement, J | 1 |
| Calvo, JR; Manchester, LC; Qi, W; Reiter, RJ; Tan, DX | 1 |
| Lopez-Burillo, S; Mayo, JC; Natarajan, M; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Hardeland, R; Lopez-Burillo, S; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Im, KJ; Jung, JG; Lee, SR; Suh, SI | 1 |
| Lopez-Burillo, S; Mayo, JC; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Bartosz, G; Grzelak, A; Macierzyńska, E | 1 |
| Antolín, I; Fernández-Marí, F; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J | 1 |
| Bartosz, G; Grzelak, A | 1 |
| Manchester, LC; Reiter, RJ; Tan, DX | 1 |
| Jang, YH; Lee, H; Lee, SR | 1 |
| Maĭs'kyĭ, VO; Oleshko, MM; Sahach, VF; Talanov, SO | 1 |
| Rimpapa, Z; Sapcanin, A; Sofić, E; Tahirović, I; Toromanović, J | 1 |
| Gulçin, I | 1 |
| Sahach, VF; Talanov, SA | 1 |
| Arruebo, MP; Fagundes, DS; Gonzalo, S; Murillo, MD; Plaza, MA | 1 |
| Goraca, A; Piechota, A | 1 |
| Bisbal, A; Carmona, M; Domínguez-Rebolledo, AE; Fernández-Santos, MR; Garde, JJ; Martínez-Pastor, F; Ramón, M; Ros-Santaella, JL | 1 |
| Henderson, G; Llorente, J; Pineda, J; Santamarta, MT | 1 |
| Anadón, A; Ares, I; Castellano, V; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Ramos, E; Romero, A | 1 |
| Castañeda-Arriaga, R; Galano, A; Pérez-González, A; Reiter, RJ; Tan, DX | 1 |
4 review(s) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and melatonin
| Article | Year |
|---|---|
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Topics: Animals; Drug Combinations; Drug Delivery Systems; Drug Design; Humans; Ligands | 2019 |
A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cell Line, Tumor; Coumaric Acids; Humans; Neuroprotective Agents; Oxidative Stress; Protein Multimerization | 2021 |
The antioxidative potential of melatonin in the skin.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Free Radical Scavengers; Free Radicals; Glycolates; Humans; Interleukin-3; Leukocytes; Luminescent Measurements; Melatonin; Mice; Mice, Hairless; Oxidative Stress; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Respiratory Burst; Singlet Oxygen; Skin; Skin Aging; Ultraviolet Rays | 2001 |
Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress.
Topics: Animals; Antioxidants; Chromans; Free Radical Scavengers; Humans; Melatonin; Oxidative Stress; Phenols | 2016 |
35 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and melatonin
| Article | Year |
|---|---|
Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres.
Topics: Alcohols; Animals; Benzothiazoles; Cell Differentiation; Fatty Alcohols; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Indoles; Membrane Proteins; Mice; Neurons; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Receptor, Notch1; Receptor, Notch2; Receptor, Notch4; Receptors, Cell Surface; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Structure-Activity Relationship; Sulfonic Acids; Transcription Factors; Transcription, Genetic | 2004 |
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.
Topics: Acetates; Aldehyde Reductase; Animals; Antioxidants; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Male; Rats; Rats, Wistar; Sorbitol | 2011 |
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.
Topics: Acetylcholinesterase; Antioxidants; Chelating Agents; Chemistry Techniques, Synthetic; Donepezil; Drug Design; Humans; Indans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Protein Conformation; Structure-Activity Relationship | 2016 |
Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Donepezil; Electrophorus; Horses; Humans; Indans; Indoles; Iron; Kinetics; Melatonin; Molecular Docking Simulation; Peptide Fragments; Piperidines; Protein Multimerization; Rats; Zinc | 2016 |
Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Binding Sites; Blood-Brain Barrier; Chromones; Copper; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; Structure-Activity Relationship | 2017 |
Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzylamines; Blood-Retinal Barrier; Butyrylcholinesterase; Cell Death; Cholinergic Agents; Cholinesterase Inhibitors; Cinnamates; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Structure-Activity Relationship | 2017 |
Inhibition of lipid peroxidation by N-acetylserotonin and its role in retinal physiology.
Topics: Animals; Antioxidants; Chromans; Free Radical Scavengers; Humans; In Vitro Techniques; Lipid Peroxidation; Melatonin; Photoreceptor Cells; Pineal Gland; Retina; Serotonin; Vitamin E | 1997 |
Effect of stobadine, U-74389G, trolox and melatonin on resistance of rat hippocampal slices to oxidative stress.
Topics: Animals; Antioxidants; Carbolines; Chromans; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Melatonin; Neuroprotective Agents; Oxidative Stress; Patch-Clamp Techniques; Pregnatrienes; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Melatonin suppresses iron-induced neurodegeneration in rat brain.
Topics: Animals; Antioxidants; Brain; Chromans; Dopamine; Glutathione; Immunohistochemistry; Infusion Pumps, Implantable; Iron; Lipid Peroxidation; Male; Melatonin; Neurodegenerative Diseases; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2000 |
Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromans; Glutathione; Glutathione Disulfide; Homeostasis; Melatonin; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats; tert-Butylhydroperoxide; Vitamin E | 2000 |
Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro.
Topics: Antioxidants; Ascorbic Acid; Chromans; Dopamine; Dose-Response Relationship, Drug; Hydroxybenzoates; Hydroxyl Radical; Iron; Melatonin; Oxidation-Reduction; Salicylates; Selegiline | 2000 |
Protective effect of beta-carbolines and other antioxidants on lipid peroxidation due to hydrogen peroxide in rat brain homogenates.
Topics: Aldehydes; Animals; Antioxidants; Ascorbic Acid; Brain Chemistry; Carbolines; Cell-Free System; Chromans; Dose-Response Relationship, Drug; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Rats; Rats, Sprague-Dawley | 2000 |
Preventive effect of several antioxidants after oxidative stress on rat brain homogenates.
Topics: Animals; Antioxidants; Benzenesulfonates; Brain; Brain Injuries; Butylated Hydroxytoluene; Carbolines; Chromans; Creatine Kinase; Cyclic N-Oxides; Inhibitory Concentration 50; Lipid Peroxidation; Male; Melatonin; Methylprednisolone; Models, Chemical; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Oxygen; Pregnatrienes; Rats; Rats, Wistar; Serotonin; Thiobarbituric Acid Reactive Substances | 2000 |
Structural damage to proteins caused by free radicals: asessment, protection by antioxidants, and influence of protein binding.
Topics: Amidines; Animals; Antioxidants; Chlorogenic Acid; Chromans; Drug Interactions; Free Radicals; Lactoglobulins; Melatonin; Muramidase; Oxidation-Reduction; Protective Agents; Protein Binding; Quercetin | 2001 |
Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminolevulinic Acid; Animals; Antioxidants; Cattle; Chromans; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; In Vitro Techniques; Mannitol; Melatonin; Oxidation-Reduction; Thymus Gland; Time Factors | 2001 |
Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants.
Topics: Amidines; Animals; Antioxidants; Ascorbic Acid; Cattle; Chromans; Copper; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Melatonin; Metals; Oxidants; Peroxides; Serum Albumin, Bovine; Time Factors | 2003 |
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.
Topics: Antioxidants; Ascorbic Acid; Benzothiazoles; Cations; Chromans; Chromatography, High Pressure Liquid; Electrochemistry; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Kynuramine; Mechanics; Melatonin; NAD; NADP; Sulfonic Acids | 2003 |
Protective effect of green tea polyphenol (-)-epigallocatechin gallate and other antioxidants on lipid peroxidation in gerbil brain homogenates.
Topics: Animals; Antioxidants; Brain; Catechin; Chromans; Dose-Response Relationship, Drug; Ferrous Compounds; Flavonoids; Gerbillinae; Hydrogen Peroxide; Inhibitory Concentration 50; Lipid Peroxidation; Male; Melatonin; Phenols; Phytotherapy; Polymers; Quaternary Ammonium Compounds; Tea; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2003 |
Oxidative damage to catalase induced by peroxyl radicals: functional protection by melatonin and other antioxidants.
Topics: Amidines; Antioxidants; Ascorbic Acid; Catalase; Chromans; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione; Melatonin; Oxidants; Oxidation-Reduction; Peroxides; Time Factors | 2003 |
Melatonin does not react rapidly with hydrogen peroxide.
Topics: Chromans; Hydrogen Peroxide; Kinetics; Melatonin; Oxidation-Reduction; Phenols; Phenolsulfonphthalein; Sulfoxides; Time Factors; Tryptophan; Tyrosine; Xylenes | 2004 |
Antioxidant activity and neuroprotective effects of zolpidem and several synthesis intermediates.
Topics: Animals; Antioxidants; Brain; Cell Death; Cells, Cultured; Chromans; Estradiol; Ferrous Compounds; Glutamic Acid; Hippocampus; Lipid Peroxidation; Liver; Male; Melatonin; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Proteins; Pyridines; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Zolpidem | 2004 |
Melatonin does not affect total antioxidant capacity of blood plasma in vitro.
Topics: Antioxidants; Chromans; Humans; Iron; Melatonin; Plasma | 2005 |
Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood.
Topics: Animals; Antioxidants; Chromans; Chromatography, High Pressure Liquid; Juglans; Male; Melatonin; Oxidation-Reduction; Radioimmunoassay; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Protective effect of propofol against kainic acid-induced lipid peroxidation in mouse brain homogenates: comparison with trolox and melatonin.
Topics: Anesthetics, Intravenous; Animals; Antioxidants; Brain Chemistry; Chromans; Excitatory Amino Acid Antagonists; Ferrous Compounds; Hydrogen Peroxide; In Vitro Techniques; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred ICR; Propofol; Quaternary Ammonium Compounds; Thiobarbituric Acid Reactive Substances | 2005 |
[Inhibitors of mitochondrial permeability transition pore prevent apoptosis of dopaminergic neurons in the mesencephalon].
Topics: Animals; Apoptosis; Chromans; Dopamine; Male; Melatonin; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Oxidopamine; Rats; Rats, Inbred WKY; Substantia Nigra; Ventral Tegmental Area | 2006 |
Inhibition of Neutral red photolysis with different antioxidants.
Topics: Antioxidants; Ascorbic Acid; Chromans; Glutathione; Melatonin; Neutral Red; Photolysis; Phototherapy; Spectrophotometry | 2007 |
Measurement of antioxidant ability of melatonin and serotonin by the DMPD and CUPRAC methods as trolox equivalent.
Topics: Antioxidants; Chromans; Decanoic Acids; Free Radicals; Melatonin; Molecular Structure; Piperidones; Serotonin | 2008 |
[Antioxidants prevent experimental hemiparkinsonism in rats].
Topics: Animals; Antioxidants; Behavior, Animal; Chromans; Disease Models, Animal; Dopamine; Male; Melatonin; Neurons; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Inbred WKY; Substantia Nigra; Ubiquinone | 2008 |
Melatonin and Trolox ameliorate duodenal LPS-induced disturbances and oxidative stress.
Topics: Aldehydes; Animals; Antioxidants; Chromans; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Lipopolysaccharides; Male; Malondialdehyde; Melatonin; Oxidative Stress; Peristalsis; Rabbits | 2010 |
[The comparison of alpha-lipoic acid, melatonin, vitamin C and trolox effectiveness in decreasing DNA stand brakes and increasing plasma antioxidant power].
Topics: Adult; Antioxidants; Ascorbic Acid; Chromans; DNA Breaks; Humans; In Vitro Techniques; Melatonin; Reference Values; Thioctic Acid; Young Adult | 2009 |
Improving the effect of incubation and oxidative stress on thawed spermatozoa from red deer by using different antioxidant treatments.
Topics: Acrosome; Animals; Antioxidants; Carotenoids; Chromans; Cryopreservation; Deer; DNA; DNA Damage; Hot Temperature; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Melatonin; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Semen Preservation; Sperm Motility; Spermatozoa; Thioctic Acid | 2010 |
Enhancement of μ-opioid receptor desensitization by nitric oxide in rat locus coeruleus neurons: involvement of reactive oxygen species.
Topics: Animals; Antioxidants; Chromans; Ditiocarb; Enkephalin, Methionine; Hydrazines; Hydrogen Peroxide; Locus Coeruleus; Male; Melatonin; Neurons; Nitric Oxide; Nitroprusside; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu | 2012 |
Cytotoxicity induced by deltamethrin and its metabolites in SH-SY5Y cells can be differentially prevented by selected antioxidants.
Topics: Acetylcysteine; Antioxidants; Benzoates; Cell Line, Tumor; Cell Survival; Chromans; Humans; Insecticides; Lipid Peroxidation; Melatonin; Neutral Red; Nitriles; Nitrites; Pyrethrins | 2012 |