6-hydroxy-1-4-5-6-tetrahydronicotinamide-adenine-dinucleotide has been researched along with 3-phosphoglycerate* in 1 studies
1 other study(ies) available for 6-hydroxy-1-4-5-6-tetrahydronicotinamide-adenine-dinucleotide and 3-phosphoglycerate
Article | Year |
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3-Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo l-Serine Synthesis.
The enzymatic mechanism of 3-phosphoglycerate to 3-phosphohydroxypyruvate oxidation, which forms the first step of the main conserved de novo serine synthesis pathway, has been revisited recently in certain microorganisms. While this step is classically considered to be catalyzed by an NAD-dependent dehydrogenase (e.g., PHGDH in mammals), evidence has shown that in Pseudomonas, Escherichia coli, and Saccharomyces cerevisiae, the PHGDH homologues act as transhydrogenases. As such, they use α-ketoglutarate, rather than NAD Topics: Feedback, Physiological; Glyceric Acids; Humans; Hydrogenation; NAD; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2019 |