Page last updated: 2024-09-04

6-fluorouracil and fluorouracil

6-fluorouracil has been researched along with fluorouracil in 5 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies (6-fluorouracil)	Trials (6-fluorouracil)	Recent Studies (post-2010) (6-fluorouracil)	Studies (fluorouracil)	Trials (fluorouracil)	Recent Studies (post-2010) (fluorouracil)
7	1	3	45,562	9,307	14,663

Protein Interaction Comparison

Protein	Taxonomy	fluorouracil (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.32
Thymidylate synthase	Mus musculus (house mouse)	1.58
Aromatase	Homo sapiens (human)	0.63

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (40.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fukushi, K; Ido, T; Irie, T	1
Finck, G; Glaw, KC; Hatfield, AK; Iverson, RK; Kunselman, SJ; Lee, JK; Lifsey, D; Loprinzi, CL; Rocke, LK; Stevens, BA	1
Lazarev, GV; Perekhodov, SN; Petrov, VP	1
FOX, JJ; WEMPEN, I	1
Brutcher, E; Christensen, D; Hennessey Smith, M; Koutlas, JB; Sellers, JB; Thompson, J; Timmons, T	1

Reviews

1 review(s) available for 6-fluorouracil and fluorouracil

Article	Year
5-Fluorouracil and Capecitabine: Assessment and Treatment of Uncommon Early-Onset Severe Toxicities Associated With Administration. Clinical journal of oncology nursing, 2018, 12-01, Volume: 22, Issue:6 Topics: Acetates; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Patient Safety; Risk Assessment; Severity of Illness Index; Survival Analysis; Uridine	2018

Article

Year

5-Fluorouracil and Capecitabine: Assessment and Treatment of Uncommon Early-Onset Severe Toxicities Associated With Administration.

Clinical journal of oncology nursing, 2018, 12-01, Volume: 22, Issue:6

Topics: Acetates; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Patient Safety; Risk Assessment; Severity of Illness Index; Survival Analysis; Uridine

2018

Trials

1 trial(s) available for 6-fluorouracil and fluorouracil

Article	Year
A randomized clinical trial of two different durations of oral cryotherapy for prevention of 5-fluorouracil-related stomatitis. Cancer, 1993, Oct-01, Volume: 72, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cryosurgery; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Stomatitis	1993

Other Studies

3 other study(ies) available for 6-fluorouracil and fluorouracil

Article	Year
Synthesis of 18F-6-fluoropurine and 18F-6-fluoro-9-beta-d-ribofuranosylpurine. The International journal of applied radiation and isotopes, 1982, Volume: 33, Issue:6 Topics: Fluorouracil; Isotope Labeling; Neoplasms; Purines; Radionuclide Imaging; Receptors, Cell Surface; Receptors, Purinergic	1982
[Regression of 4th-stage cancer of the rectum]. Khirurgiia, 1996, Issue:2 Topics: Adenocarcinoma; Combined Modality Therapy; Female; Fluorouracil; Humans; Middle Aged; Rectal Neoplasms; Rectum; Remission Induction	1996
PYRIMIDINES. II. SYNTHESIS OF 6-FLUOROURACIL. Journal of medicinal chemistry, 1964, Volume: 7 Topics: Anti-Infective Agents; Antifungal Agents; Bacteria; Chemistry, Pharmaceutical; Fluorouracil; Fungi; Pharmacology; Pyrimidines; Research; Spectrum Analysis; Yeasts	1964