Page last updated: 2024-09-03

6-fluoromevalonolactone and squalestatin 1

6-fluoromevalonolactone has been researched along with squalestatin 1 in 2 studies

Compound Research Comparison

Studies (6-fluoromevalonolactone)	Trials (6-fluoromevalonolactone)	Recent Studies (post-2010) (6-fluoromevalonolactone)	Studies (squalestatin 1)	Trials (squalestatin 1)	Recent Studies (post-2010) (squalestatin 1)
10	0	1	104	0	26

Protein Interaction Comparison

Protein	Taxonomy	squalestatin 1 (IC50)
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.0005
Protein farnesyltransferase subunit beta	Rattus norvegicus (Norway rat)	0.012
Squalene synthase	Rattus norvegicus (Norway rat)	0.0063
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Rattus norvegicus (Norway rat)	0.012

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Arnaboldi, L; Corsini, A; Ferri, N; Fumagalli, R; Granata, A; Paoletti, R; Quarato, P	1
Henneman, L; Kulik, W; van Cruchten, AG; Waterham, HR	1

Other Studies

2 other study(ies) available for 6-fluoromevalonolactone and squalestatin 1

Article	Year
[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997, Volume: 191, Issue:2 Topics: Animals; Aorta; Benzodiazepines; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cholesterol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Oligopeptides; Rats; Rats, Sprague-Dawley; Thiophenes; Tricarboxylic Acids	1997
Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. Biochimica et biophysica acta, 2011, Volume: 1811, Issue:4 Topics: Alkyl and Aryl Transferases; Bone Density Conservation Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Liquid; Diphosphonates; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Farnesyltranstransferase; Fibroblasts; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lymphocytes; Mevalonic Acid; Pamidronate; Prenylation; Signal Transduction; Tandem Mass Spectrometry; Terpenes; Tricarboxylic Acids; Zoledronic Acid	2011

Article

Year

[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997, Volume: 191, Issue:2

Topics: Animals; Aorta; Benzodiazepines; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cholesterol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Oligopeptides; Rats; Rats, Sprague-Dawley; Thiophenes; Tricarboxylic Acids

1997

Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS.

Biochimica et biophysica acta, 2011, Volume: 1811, Issue:4

Topics: Alkyl and Aryl Transferases; Bone Density Conservation Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Liquid; Diphosphonates; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Farnesyltranstransferase; Fibroblasts; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lymphocytes; Mevalonic Acid; Pamidronate; Prenylation; Signal Transduction; Tandem Mass Spectrometry; Terpenes; Tricarboxylic Acids; Zoledronic Acid

2011