Page last updated: 2024-09-03

6-fluoromevalonolactone and mevalonic acid

6-fluoromevalonolactone has been researched along with mevalonic acid in 9 studies

Compound Research Comparison

Studies
(6-fluoromevalonolactone)
Trials
(6-fluoromevalonolactone)
Recent Studies (post-2010)
(6-fluoromevalonolactone)
Studies
(mevalonic acid)
Trials
(mevalonic acid)
Recent Studies (post-2010) (mevalonic acid)
10013,81033922

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's6 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cuthbert, JA; Lipsky, PE3
d'Orchymont, H; Ducep, JB; Jung, MJ; Nave, JF; Piriou, F1
Carrel, JE; Doom, JP; McCormick, JP1
Ku, EC1
Iwama, A; Nara, Y; Sawamura, M; Yamori, Y1
Arnaboldi, L; Corsini, A; Ferri, N; Fumagalli, R; Granata, A; Paoletti, R; Quarato, P1
Henneman, L; Kulik, W; van Cruchten, AG; Waterham, HR1

Other Studies

9 other study(ies) available for 6-fluoromevalonolactone and mevalonic acid

ArticleYear
Negative regulation of cell proliferation by mevalonate or one of the mevalonate phosphates.
    The Journal of biological chemistry, 1991, Sep-25, Volume: 266, Issue:27

    Topics: Cell Division; Cell Line; DNA; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, LDL; Lovastatin; Lymphocytes; Mevalonic Acid; Sterols

1991
Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation.
    The Journal of biological chemistry, 1990, Oct-25, Volume: 265, Issue:30

    Topics: Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lipid Metabolism; Lipoproteins, LDL; Lovastatin; Lymphocyte Activation; Mevalonic Acid; Proteins; Sterols

1990
Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate.
    The Biochemical journal, 1985, Apr-01, Volume: 227, Issue:1

    Topics: Animals; Anticholesteremic Agents; Carboxy-Lyases; Cholesterol; Chromatography, Thin Layer; Hemiterpenes; In Vitro Techniques; Kinetics; Lipids; Liver; Mevalonic Acid; Organophosphorus Compounds; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Rats; Rats, Inbred Strains

1985
Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.
    Experientia, 1986, Jul-15, Volume: 42, Issue:7

    Topics: Animals; Cantharidin; Coleoptera; Male; Mevalonic Acid; Reproduction

1986
Suppression of the proliferation of Ras-transformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism.
    Cancer research, 1995, Apr-15, Volume: 55, Issue:8

    Topics: Animals; Carboxy-Lyases; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cholesterol; DNA Replication; Genes, ras; Humans; Interleukin-3; Kinetics; Mevalonic Acid; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1995
Regulation of fatty acid biosynthesis by intermediates of the cholesterol biosynthetic pathway.
    Biochemical and biophysical research communications, 1996, Aug-05, Volume: 225, Issue:1

    Topics: Anticholesteremic Agents; Carboxy-Lyases; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Homeostasis; Humans; Kinetics; Liver Neoplasms; Lovastatin; Mevalonic Acid; Structure-Activity Relationship; Tumor Cells, Cultured

1996
Effect of lovastatin and fluoromevalonate on phosphatidylinositol 3-kinase activity stimulated with PDGF.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Carboxy-Lyases; Cell Division; Enzyme Inhibitors; In Vitro Techniques; Lovastatin; Male; Mevalonic Acid; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thymidine

1995
[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997, Volume: 191, Issue:2

    Topics: Animals; Aorta; Benzodiazepines; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cholesterol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Oligopeptides; Rats; Rats, Sprague-Dawley; Thiophenes; Tricarboxylic Acids

1997
Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS.
    Biochimica et biophysica acta, 2011, Volume: 1811, Issue:4

    Topics: Alkyl and Aryl Transferases; Bone Density Conservation Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Liquid; Diphosphonates; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Farnesyltranstransferase; Fibroblasts; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lymphocytes; Mevalonic Acid; Pamidronate; Prenylation; Signal Transduction; Tandem Mass Spectrometry; Terpenes; Tricarboxylic Acids; Zoledronic Acid

2011