6-fluoromevalonolactone has been researched along with lovastatin in 4 studies
| Studies (6-fluoromevalonolactone) | Trials (6-fluoromevalonolactone) | Recent Studies (post-2010) (6-fluoromevalonolactone) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
|---|---|---|---|---|---|
| 10 | 0 | 1 | 4,828 | 698 | 873 |
| Protein | Taxonomy | 6-fluoromevalonolactone (IC50) | lovastatin (IC50) |
|---|---|---|---|
| Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
| Integrin beta-2 | Homo sapiens (human) | 3.09 | |
| Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
| Neutrophil elastase | Homo sapiens (human) | 0.027 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
| Integrin alpha-L | Homo sapiens (human) | 3.09 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cuthbert, JA; Lipsky, PE | 2 |
| Ku, EC | 1 |
| Iwama, A; Nara, Y; Sawamura, M; Yamori, Y | 1 |
4 other study(ies) available for 6-fluoromevalonolactone and lovastatin
| Article | Year |
|---|---|
Negative regulation of cell proliferation by mevalonate or one of the mevalonate phosphates.
Topics: Cell Division; Cell Line; DNA; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, LDL; Lovastatin; Lymphocytes; Mevalonic Acid; Sterols | 1991 |
Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation.
Topics: Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lipid Metabolism; Lipoproteins, LDL; Lovastatin; Lymphocyte Activation; Mevalonic Acid; Proteins; Sterols | 1990 |
Regulation of fatty acid biosynthesis by intermediates of the cholesterol biosynthetic pathway.
Topics: Anticholesteremic Agents; Carboxy-Lyases; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Homeostasis; Humans; Kinetics; Liver Neoplasms; Lovastatin; Mevalonic Acid; Structure-Activity Relationship; Tumor Cells, Cultured | 1996 |
Effect of lovastatin and fluoromevalonate on phosphatidylinositol 3-kinase activity stimulated with PDGF.
Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Carboxy-Lyases; Cell Division; Enzyme Inhibitors; In Vitro Techniques; Lovastatin; Male; Mevalonic Acid; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thymidine | 1995 |