6-ethylguanine has been researched along with o-(6)-methylguanine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (57.14) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; Golding, BT; Griffin, RJ; Kanugula, S; Lembicz, NK; Newell, DR; Pegg, AE | 1 |
| Arris, CE; Bentley, J; Boyle, FT; Curtin, NJ; Davies, TG; Endicott, JA; Gibson, AE; Golding, BT; Grant, S; Griffin, RJ; Jewsbury, P; Johnson, LN; Mesguiche, V; Newell, DR; Noble, ME; Tucker, JA; Whitfield, HJ | 1 |
| Caflisch, A; Dey, F; Huang, D; Kolb, P | 1 |
| Ambatzi, P; Bousiotou, V; Davaris, G; Haritopoulos, G; Kyrtopoulos, SA; Pangalis, G; Souliotis, VL | 1 |
| Abbondandolo, A; Bonatti, S; Cercignani, G; De Ferrari, M; Ipata, PL; Rocco, M; Tozzi, MG; Viaggi, S | 1 |
| Den Engelse, L; Scherer, E; Van Den Berg, T; Vermeulen, E; Winterwerp, HH | 1 |
| Kyrtopoulos, SA; Souliotis, VL | 1 |
| Cawkwell, L; Georgiadis, P; Margison, GP; Patel, D; Potter, PM; Swann, PF; Wilkinson, MC | 1 |
| Basu, AK; Connors, TD; Dogliotti, E; Ellison, KS; Essigmann, JM | 1 |
| Rajewsky, MF; Samson, L; Thomale, J | 1 |
| Horie, Y; Huh, NH; Kuroki, T; Rajewsky, MF; Satoh, MS; Thomale, J | 1 |
| Graves, RJ; Li, BF; Swann, PF | 1 |
| Anderson, MW; Darden, TA; Deerfield, DW; Hoel, DG; Pedersen, LG | 1 |
| Kalnik, M; Li, BF; Patel, DJ; Swann, PF | 1 |
| Kleihues, P; von Hofe, E | 1 |
| Saffhill, R | 1 |
| Lemaître, M; Verly, WG | 1 |
| Cao, EH; Delihas, NC; Setlow, RB | 1 |
| Lindahl, T; Sedgwick, B | 1 |
| Lemaître, M; Renard, A; Verly, WG | 1 |
| Hughes, SH; Moschel, RC; Pauly, GT | 1 |
| Li, BF; Liem, LK; Lim, A | 1 |
| Bishop, RE; Dolan, ME; Dunn, LL; Moschel, RC; Pauly, GT | 1 |
| Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
| Gerson, SL; Liu, L; Markowitz, S | 1 |
| Engelbergs, J; Rajewsky, MF; Schweer, T; Thomale, J | 1 |
| Abbondandolo, A; Bonatti, S; Pigullo, S; Simili, M | 1 |
| Moschel, RC; Pauly, GT | 1 |
1 review(s) available for 6-ethylguanine and o-(6)-methylguanine
| Article | Year |
|---|---|
Enzymology of repair of DNA adducts produced by N-nitroso compounds.
Topics: Alkylation; Animals; Base Sequence; Cells, Cultured; DNA Repair; Guanine; Humans; Methylnitronitrosoguanidine; Nitroso Compounds | 1984 |
27 other study(ies) available for 6-ethylguanine and o-(6)-methylguanine
| Article | Year |
|---|---|
Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine.
Topics: Antineoplastic Agents, Alkylating; Cell Extracts; Dacarbazine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Guanine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Tumor Cells, Cultured | 2000 |
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Division; Crystallography, X-Ray; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Guanine; Humans; Models, Molecular; Protein Serine-Threonine Kinases; Ribose; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model.
Topics: Humans; Models, Molecular; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Quantitative Structure-Activity Relationship; Static Electricity; Thermodynamics | 2008 |
Novel, sensitive assays for O6-alkylguanine and its repair and their application to studies of the molecular epidemiology of this lesion in human populations.
Topics: DNA Damage; DNA Repair; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase | 1991 |
The role of nucleotide pool alkylation in the induction of numerical chromosome aberrations.
Topics: Adenosine Deaminase; Alkylation; Aneuploidy; Chromosome Aberrations; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Nucleotides; Purine-Nucleoside Phosphorylase | 1989 |
Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea.
Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; DNA Repair; Esophagus; Ethylnitrosourea; Female; Guanine; Immunoenzyme Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Substrate Specificity | 1989 |
A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
Topics: Animals; DNA; DNA Damage; DNA Repair; Escherichia coli; Guanine; In Vitro Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
Topics: Alkylating Agents; Amino Acids; Chromatography, High Pressure Liquid; Deoxyribonucleotides; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Guanine; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine | 1989 |
Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase.
Topics: Animals; Base Sequence; Cell Line; Chromosomes; DNA Repair; Genetic Vectors; Guanine; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Polymerase Chain Reaction; Transfection | 1989 |
Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.
Topics: Alkylation; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Kinetics; Methylnitrosourea; Mutation; Thymine | 1988 |
Acquisition of resistance to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride in V79 cells through increased removal of O6-alkylguanine.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; DNA Repair; Drug Resistance; Guanine; Methyltransferases; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase | 1987 |
Repair of synthetic oligonucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine, by O6-alkylguanine-DNA alkyltransferase.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine | 1987 |
A theoretical study of the effect of methylation or ethylation at O6-guanine in the structure and energy of DNA double strands.
Topics: Alkylation; Base Sequence; Chemical Phenomena; Chemistry, Physical; Computer Simulation; DNA; Guanine; Hydrogen Bonding; Methylation; Molecular Conformation; Structure-Activity Relationship; Thermodynamics | 1988 |
Synthesis and structural studies by nuclear magnetic resonance of dodecadeoxynucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine.
Topics: Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymine | 1987 |
Comparative studies on hepatic DNA alkylation in rats by N-nitrosomethylethylamine and N-nitrosodimethylamine plus N-nitrosodiethylamine.
Topics: Alkylation; Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Male; Mathematics; Rats; Rats, Inbred F344 | 1986 |
The competitive miscoding of O6-methylguanine and O6-ethylguanine and the possible importance of cellular deoxynucleoside 5'-triphosphate pool sizes in mutagenesis and carcinogenesis.
Topics: Deoxyribonucleotides; DNA Polymerase I; DNA Replication; Guanine; Mutation; Templates, Genetic | 1986 |
[The same alkyl acceptor acts in the repair of DNA containing O6-methylguanine or O6-ethylguanine].
Topics: Alkylation; Animals; Chromatin; DNA Repair; Guanine; Liver; Nucleoproteins; Rats | 1984 |
A common mechanism for repair of O6-methylguanine and O6-ethylguanine in DNA.
Topics: Alkylating Agents; DNA Repair; Escherichia coli; Guanine; Mutagens; Mutation | 1982 |
A common chromatin factor involved in the repair of O6-methylguanine and O6-ethylguanine lesions in DNA.
Topics: Alkylation; Animals; Chromatin; DNA Repair; Guanine; Liver; Rats | 1982 |
Response of repair-competent and repair-deficient Escherichia coli to three O6-substituted guanines and involvement of methyl-directed mismatch repair in the processing of O6-methylguanine residues.
Topics: Base Sequence; Codon; DNA Repair; DNA Replication; Escherichia coli; Genes, Bacterial; Guanine; Methyltransferases; Models, Genetic; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Plasmids | 1994 |
Specificities of human, rat and E. coli O6-methylguanine-DNA methyltransferases towards the repair of O6-methyl and O6-ethylguanine in DNA.
Topics: Animals; Bacterial Proteins; Base Sequence; DNA; DNA Repair; Escherichia coli; Escherichia coli Proteins; Guanine; Humans; Kinetics; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Rats; Substrate Specificity; Transcription Factors | 1994 |
The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene.
Topics: Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; Codon; DNA Damage; DNA Repair; Genes, ras; Guanine; Methyltransferases; Molecular Sequence Data; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Transfection | 1993 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Topics: Antineoplastic Agents, Alkylating; Carmustine; Colonic Neoplasms; Dacarbazine; DNA Adducts; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; DNA; DNA Adducts; DNA Repair; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagens; Mutation; Rats | 2000 |
Induction of apoptosis and inhibition of signalling pathways by alkylated purines.
Topics: Adenine; Alkylation; Androstadienes; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line; Cricetinae; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibroblasts; G1 Phase; Genes, p53; Guanine; MAP Kinase Signaling System; Mutation; Phosphorylation; Purines; Resting Phase, Cell Cycle; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Wortmannin | 2000 |
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
Topics: Base Pair Mismatch; Colonic Neoplasms; Escherichia coli; Genetic Vectors; Guanine; Humans; Kidney; Lac Operon; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection | 2001 |