6-ethylguanine has been researched along with o(6)-benzylguanine in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; Golding, BT; Griffin, RJ; Kanugula, S; Lembicz, NK; Newell, DR; Pegg, AE | 1 |
| Arris, CE; Bentley, J; Boyle, FT; Curtin, NJ; Davies, TG; Endicott, JA; Gibson, AE; Golding, BT; Grant, S; Griffin, RJ; Jewsbury, P; Johnson, LN; Mesguiche, V; Newell, DR; Noble, ME; Tucker, JA; Whitfield, HJ | 1 |
| Caflisch, A; Dey, F; Huang, D; Kolb, P | 1 |
| Bronstein, SM; Hooth, MJ; Skopek, TR; Swenberg, JA | 1 |
| Hughes, SH; Moschel, RC; Pauly, GT | 1 |
| Bishop, RE; Dolan, ME; Dunn, LL; Moschel, RC; Pauly, GT | 1 |
| Bishop, RE; Moschel, RC; Pauly, GT | 1 |
| Gerson, SL; Liu, L; Markowitz, S | 1 |
| Moschel, RC; Pauly, GT | 1 |
9 other study(ies) available for 6-ethylguanine and o(6)-benzylguanine
| Article | Year |
|---|---|
Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine.
Topics: Antineoplastic Agents, Alkylating; Cell Extracts; Dacarbazine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Guanine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Tumor Cells, Cultured | 2000 |
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Division; Crystallography, X-Ray; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Guanine; Humans; Models, Molecular; Protein Serine-Threonine Kinases; Ribose; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model.
Topics: Humans; Models, Molecular; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Quantitative Structure-Activity Relationship; Static Electricity; Thermodynamics | 2008 |
Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine.
Topics: Alkylation; Cell Line, Transformed; Cell Survival; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lymphocytes; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype | 1992 |
Response of repair-competent and repair-deficient Escherichia coli to three O6-substituted guanines and involvement of methyl-directed mismatch repair in the processing of O6-methylguanine residues.
Topics: Base Sequence; Codon; DNA Repair; DNA Replication; Escherichia coli; Genes, Bacterial; Guanine; Methyltransferases; Models, Genetic; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Plasmids | 1994 |
The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene.
Topics: Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; Codon; DNA Damage; DNA Repair; Genes, ras; Guanine; Methyltransferases; Molecular Sequence Data; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Transfection | 1993 |
O6-ethylguanine and O6-benzylguanine incorporated site-specifically in codon 12 of the rat H-ras gene induce semi-targeted as well as targeted mutations in Rat4 cells.
Topics: Animals; Base Sequence; Cell Line; Cell Line, Transformed; Clone Cells; Codon; DNA; Genes, ras; Guanine; Molecular Sequence Data; Mutation; Rats | 1996 |
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Topics: Antineoplastic Agents, Alkylating; Carmustine; Colonic Neoplasms; Dacarbazine; DNA Adducts; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
Topics: Base Pair Mismatch; Colonic Neoplasms; Escherichia coli; Genetic Vectors; Guanine; Humans; Kidney; Lac Operon; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection | 2001 |