6-ethylguanine has been researched along with ethylnitrosourea in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (46.67) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bronstein, SM; Skopek, TR; Swenberg, JA | 1 |
| Bronstein, SM; Hooth, MJ; Skopek, TR; Swenberg, JA | 1 |
| Eberle, G; Huh, NH; Nehls, P; Rajewsky, MF; Thomale, J | 1 |
| Den Engelse, L; Scherer, E; Van Den Berg, T; Vermeulen, E; Winterwerp, HH | 1 |
| Rajewsky, MF; Samson, L; Thomale, J | 1 |
| Burns, PA; Glickman, BW; Gordon, AJ; Kunsmann, K | 1 |
| Berger, J; Nehls, P; Rajewsky, MF; Spiess, E; Weber, E | 1 |
| Huh, N; Kuroki, T; Rajewsky, MF; Satoh, MS | 1 |
| Huh, NH; Rajewsky, MF | 1 |
| Ehling, UH; Mohn, GR; Neuhäuser-Klaus, A; van Zeeland, AA | 1 |
| Huh, N; Rajewsky, MF | 1 |
| Nehls, P; Rajewsky, MF | 1 |
| Guttenplan, JB | 1 |
| Renard, A; Verly, WG | 1 |
| Müller, R; Rajewsky, MF | 1 |
| Chang, MJ; Hart, RW; Koestner, A | 1 |
| Jansen, JG; Mohn, GR; Tates, AD; van Teijlingen, CM; van Zeeland, AA; Vrieling, H | 1 |
| Buschfort, C; Müller, MR; Rajewsky, MF; Seeber, S; Seiler, F; Thomale, J | 1 |
| Cerutti, P; Pourzand, C | 1 |
| Hochleitner, K; Rajewsky, MF; Thomale, J | 1 |
| Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
| Baan, RA; Berends, F; Hochleitner, K; Lohman, PH; Luiten-Schuite, A; Mientjes, EJ; Rajewsky, MF; Thomale, J; van Delft, JH | 1 |
| Baan, RA; Berends, F; Bergmans, A; Borsboom, Y; Lohman, PH; Luiten-Schuite, A; Mientjes, EJ; van Delft, JH; van der Wolf, E | 1 |
| Engelbergs, J; Galhoff, A; Rajewsky, MF; Thomale, J | 1 |
| Emura, M; Kamino, K; Mohr, U; Seiler, F; Thomale, J | 1 |
| Buschfort, C; Lensing, C; Müller, MR; Rajewsky, MF; Seeber, S; Thomale, J | 1 |
| Engelbergs, J; Rajewsky, MF; Schweer, T; Thomale, J | 1 |
| Den Engelse, L; Heyting, C; Huigen, A | 1 |
| Abbruzzese, JL; Chang, P; Firozi, PF; Jiao, L; Lai, D; Li, D | 1 |
| Bartleman, AP; Kirkland, JB; Kostecki, LM; Linford, G; Lizotte, M; Thomas, M; Toxopeus, L | 1 |
30 other study(ies) available for 6-ethylguanine and ethylnitrosourea
| Article | Year |
|---|---|
Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells.
Topics: B-Lymphocytes; Cell Line; DNA Repair; Ethylnitrosourea; Guanine; Humans; Kinetics; Methyltransferases; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidine Dimers; Substrate Specificity; Thymine; Time Factors | 1992 |
Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine.
Topics: Alkylation; Cell Line, Transformed; Cell Survival; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lymphocytes; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype | 1992 |
Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.
Topics: Animals; Carmustine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; DNA; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1990 |
Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea.
Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; DNA Repair; Esophagus; Ethylnitrosourea; Female; Guanine; Immunoenzyme Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Substrate Specificity | 1989 |
Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.
Topics: Alkylation; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Kinetics; Methylnitrosourea; Mutation; Thymine | 1988 |
Influence of neighboring base sequence on the distribution and repair of N-ethyl-N-nitrosourea-induced lesions in Escherichia coli.
Topics: Base Sequence; DNA Repair; Escherichia coli; Ethylnitrosourea; Guanine; Methylnitronitrosoguanidine; Mutation; Thymine | 1988 |
Distribution of O6-ethylguanine in DNA exposed to ethylnitrosourea in vitro as visualized by electron microscopy using a monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; DNA; DNA Damage; Ethylnitrosourea; Guanine; Microscopy, Electron; Rats; Software | 1988 |
Enzymatic removal of O6-ethylguanine from mitochondrial DNA in rat tissues exposed to N-ethyl-N-nitrosourea in vivo.
Topics: Animals; Brain; Cell Nucleus; DNA Repair; DNA, Mitochondrial; Ethylnitrosourea; Guanine; Kidney; Kinetics; Male; Mitochondria; Mitochondria, Liver; Rats; Rats, Inbred Strains; Thymidine | 1988 |
Enzymatic elimination of O6-ethylguanine from the DNA of ethylnitrosourea-exposed normal and malignant rat brain cells grown under cell culture versus in vivo conditions.
Topics: Animals; Brain Neoplasms; DNA; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Rats; Tumor Cells, Cultured | 1988 |
Quantitative comparison of genetic effects of ethylating agents on the basis of DNA adduct formation. Use of O6-ethylguanine as molecular dosimeter for extrapolation from cells in culture to the mouse.
Topics: Alkylating Agents; Animals; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA; Environmental Exposure; Escherichia coli; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Lung; Methylnitronitrosoguanidine; Mice; Mutation; Structure-Activity Relationship; Sulfuric Acid Esters | 1985 |
Enzymatic elimination of O6-ethylguanine and stability of O4-ethylthymine in the DNA of malignant neural cell lines exposed to N-ethyl-N-nitrosourea in culture.
Topics: Animals; Cells, Cultured; Clone Cells; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Neurons; Rats; Thymine | 1986 |
Differential formation of O6-ethylguanine in the DNA of rat brain chromatin fibers of different folding levels exposed to N-ethyl-N-nitrosourea in vitro.
Topics: Alkylation; Animals; Brain; Chromatin; DNA; Ethylnitrosourea; Guanine; In Vitro Techniques; Nitrosourea Compounds; Nucleosomes; Rats | 1985 |
Mutagenesis and O6-ethylguanine levels in DNA from N-nitroso-N-ethylurea-treated Salmonella typhimurium: evidence for a high mutational efficiency of O6-ethylguanine.
Topics: DNA, Bacterial; Ethylnitrosourea; Guanine; Mutagenicity Tests; Mutagens; Mutation; Nitrosourea Compounds; Salmonella typhimurium | 1984 |
Repair of O6-ethylguanine DNA lesions in isolated cell nuclei. Presence of the activity in the chromatin proteins.
Topics: Animals; Cell Nucleus; Chemical Phenomena; Chemistry; Chromatin; Chromatography, Paper; Diethylnitrosamine; DNA Repair; Ethylnitrosourea; Guanine; Liver; Male; Rats; Rats, Inbred Strains | 1983 |
Elimination of O6-ethylguanine from the DNA of brain, liver, and other rat tissues exposed to ethylnitrosourea at different stages of prenatal development.
Topics: Animals; Brain; DNA; Ethylnitrosourea; Female; Fetus; Guanine; Kinetics; Liver; Male; Nitrosourea Compounds; Pregnancy; Rats | 1983 |
Retention of promutagenic O6-ethylguanine in the DNA of various rat tissues following transplacental inoculation with ethylnitrosourea.
Topics: Alkylation; Animals; Brain; DNA; DNA Replication; Ethylnitrosourea; Female; Guanine; Kidney; Liver; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1980 |
Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
Topics: Adenine; Animals; Base Composition; Base Sequence; Carcinogens; DNA Adducts; DNA, Complementary; Drug Resistance; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocytes; Thioguanine; Thymidine | 1995 |
Capacity of individual chronic lymphatic leukemia lymphocytes and leukemic blast cells for repair of O6-ethylguanine in DNA: relation to chemosensitivity in vitro and treatment outcome.
Topics: Acute Disease; Carmustine; Cyclophosphamide; Cytarabine; DNA Repair; Doxorubicin; Drug Resistance; Ethylnitrosourea; Glutathione; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphocytes; Treatment Outcome | 1994 |
Mutagenesis of H-ras codons 11 and 12 in human fibroblasts by N-ethyl-N-nitrosourea.
Topics: Base Sequence; Codon; Ethylnitrosourea; Fibroblasts; Genes, ras; Guanine; Humans; Molecular Sequence Data; Point Mutation; Polymorphism, Restriction Fragment Length | 1993 |
Differential formation and repair of the mutagenic DNA alkylation product O6-ethylguanine in transcribed and nontranscribed genes of the rat.
Topics: Alkylation; Animals; Carcinoma, Hepatocellular; Cell Line; DNA Repair; DNA, Neoplasm; Ethylnitrosourea; Gene Expression; Guanine; Liver Neoplasms; Mutagenesis; Rats; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Formation and persistence of O6-ethylguanine in genomic and transgene DNA in liver and brain of lambda(lacZ) transgenic mice treated with N-ethyl-N-nitrosourea.
Topics: Animals; Bacteriophage lambda; Brain; DNA; DNA Repair; Ethylnitrosourea; Female; Genome; Guanine; Immunoblotting; Lac Operon; Liver; Mice; Mice, Transgenic; Mutagenicity Tests; Mutagens; Polymerase Chain Reaction; Sensitivity and Specificity | 1996 |
DNA adducts, mutant frequencies, and mutation spectra in various organs of lambda lacZ mice exposed to ethylating agents.
Topics: Animals; Bone Marrow; Brain; Diethylnitrosamine; DNA Adducts; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Guanine; Lac Operon; Liver; Mice; Mice, Transgenic; Mutagens | 1998 |
Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea.
Topics: Alkylation; Animals; Animals, Genetically Modified; DNA Adducts; DNA Repair; DNA, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Rats; Transcription, Genetic | 1998 |
Formation and persistence of the miscoding DNA alkylation product O6-ethylguanine in male germ cells of the hamster.
Topics: Animals; Antibodies, Monoclonal; Carcinogens; Cricetinae; Diethylnitrosamine; DNA; DNA Adducts; DNA Damage; DNA Repair; Ethylnitrosourea; Fluorescent Antibody Technique, Indirect; Guanine; Male; Mesocricetus; Spermatogonia | 1997 |
DNA repair and cellular resistance to alkylating agents in chronic lymphocytic leukemia.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Nucleus; Chlorambucil; Cyclophosphamide; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance, Neoplasm; Ethylnitrosourea; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Prednisone; Vincristine | 1997 |
DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; DNA; DNA Adducts; DNA Repair; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagens; Mutation; Rats | 2000 |
Repair of ethylnitrosourea-induced DNA damage in the newborn rat. I. Alkali-labile lesions and in situ breaks.
Topics: Adenine; Alkylating Agents; Animals; Animals, Newborn; Brain; DNA; DNA Damage; DNA Repair; Ethylnitrosourea; Female; Guanine; Hydrogen-Ion Concentration; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Sodium Hydroxide | 1980 |
Polymorphisms of phase II xenobiotic-metabolizing and DNA repair genes and in vitro N-ethyl-N-nitrosourea-induced O6-ethylguanine levels in human lymphocytes.
Topics: Aged; DNA Repair Enzymes; Ethylnitrosourea; Female; Guanine; Humans; Lymphocytes; Male; Metabolic Detoxication, Phase II; Middle Aged; Polymorphism, Genetic; Xenobiotics | 2007 |
Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow.
Topics: Animals; Bone Marrow; Chromosomal Instability; Chromosome Aberrations; Comet Assay; DNA Adducts; DNA Repair; Ethylnitrosourea; Guanine; Male; Micronucleus Tests; Niacin; Rats; Rats, Long-Evans | 2007 |