6-codeinone has been researched along with morphinone* in 1 studies
1 other study(ies) available for 6-codeinone and morphinone
Article | Year |
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Microbial degradation of the morphine alkaloids: identification of morphine as an intermediate in the metabolism of morphine by Pseudomonas putida M10.
A strain of Pseudomonas putida was isolated by selective enrichment with morphine that was capable of utilising morphine as a primary source of carbon and energy for growth. Experiments with whole cells showed that both morphine and codeine, but not thebaine, could be utilised. A novel NADP-dependent dehydrogenase, morphine dehydrogenase, was purified from crude cell extracts and was shown to be capable of oxidising morphine and codeine to morphinone and codeinone, respectively. This NADP-dependent morphine dehydrogenase was not observed in any other species of pseudomonads examined and was quite distinct from the beta-hydroxysteroid dehydrogenase found in Pseudomonas testosteroni, which had previously been shown to have activity against morphine. Topics: Biodegradation, Environmental; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Hydromorphone; Magnetic Resonance Spectroscopy; Molecular Structure; Morphine; NADPH Dehydrogenase; Oxidation-Reduction; Pseudomonas; Thebaine | 1990 |