6-chloromelatonin has been researched along with melatonin in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (22.22) | 18.7374 |
| 1990's | 19 (42.22) | 18.2507 |
| 2000's | 13 (28.89) | 29.6817 |
| 2010's | 2 (4.44) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Clemens, JA; Crowell, TA; Flaugh, ME; Sawyer, BD | 1 |
| Dubocovich, ML | 1 |
| Biella, G; Duranti, A; Fraschini, F; Lucini, V; Salvatori, A; Spadoni, G; Stankov, B | 1 |
| Copinga, S; Dubocovich, ML; Grol, CJ; Horn, AS; Tepper, PG | 1 |
| Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM | 1 |
| Balsamini, C; Di Giacomo, B; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Pannacci, M; Plazzi, PV; Rivara, S; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Di Giacomo, B; Diamantini, G; Esposti, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V | 1 |
| Amossé, C; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Dromaint, S; Galizzi, JP; Guillaumet, G; Lahaye-Brasseur, C; Le Gall, A; Lefoulon, F; Lesieur, D; Mailliet, F; Malpaux, B; Nagel, N; Renard, P; Rodriguez, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP | 1 |
| Laborda, P; Shi, XC; Wang, SY | 1 |
| Pang, CS; Pang, SF | 1 |
| Lu, Y; Pang, SF; Yuan, H | 1 |
| Kehajova, J; Persengiev, S | 1 |
| Dubocovich, ML; Fang, JM | 1 |
| Petterborg, LJ; Reiter, RJ; Richardson, BA; Vaughan, GM; Vaughan, MK | 1 |
| Bok, D; Horwitz, J; Wiechmann, AF | 1 |
| Clemens, JA; Flaugh, ME | 1 |
| Cardinali, DP; Keller Sarmiento, MI; Vacas, MI | 1 |
| King, TS; Petterborg, LJ; Reiter, RJ; Richardson, BA; Spanel-Borowski, K | 1 |
| Besharse, JC; Dunis, DA | 1 |
| Johnson, LY; King, TS; Petterborg, LJ; Reiter, RJ; Richardson, BA; Smith, I; Vaughan, MK | 1 |
| Clemens, JA; Flaugh, ME; Parli, J; Sawyer, BD | 1 |
| Gan, J; Iuvone, PM | 1 |
| Dubocovich, ML; Popova, JS | 1 |
| Behnke, B; Koopmann, K; Krone, W; Müller-Wieland, D | 1 |
| Lee, PP; Pang, SF; Poon, AM; Song, Y | 1 |
| Pang, SF; Wang, XL; Yuan, H | 1 |
| Crocker, C; Niles, LP; Ying, SW | 1 |
| Hu, DN; Roberts, JE; Wishart, JF | 1 |
| Hu, DN; McCormick, SA; Roberts, JE | 1 |
| Bucher, B; Gauer, F; Masson-Pévet, M; Pévet, P | 1 |
| Hu, DN; Roberts, JE; Wiechmann, AF | 1 |
| Chignell, CF; Hu, DN; Martinez, L; Roberts, JE | 1 |
| Burkhardt, S; Dose, A; Hardeland, R; Poeggeler, B; Schoenke, M; Thuermann, S | 1 |
| Kang, HS; Kang, SG; Kim, H; Lee, BJ; Lee, CK; Moon, DH; Shin, CS; Yoon, YD | 1 |
| Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E | 1 |
| Sun, RQ; Tu, Y; Willis, WD | 1 |
| Ajjimaporn, A; Ebadi, M; Govitrapong, P; Ho, B; Klongpanichapak, S; Sawlom, S; Shavali, S | 1 |
| Prada, C; Udin, SB | 1 |
| Lanoix, D; Ouellette, R; Vaillancourt, C | 1 |
| Fujinoki, M | 1 |
| Carazo, A; Casado, J; de la Cueva, P; León, J; Maté, A; Muñoz de Rueda, P; Quiles, R; Ruíz, S; Ruíz-Extremera, A; Salmerón, J; Sanjuán, L | 1 |
1 review(s) available for 6-chloromelatonin and melatonin
| Article | Year |
|---|---|
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship | 2020 |
44 other study(ies) available for 6-chloromelatonin and melatonin
| Article | Year |
|---|---|
Synthesis and evaluation of the antiovulatory activity of a variety of melatonin analogues.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Melatonin; Ovulation; Rats; Serotonin; Structure-Activity Relationship | 1979 |
Characterization of a retinal melatonin receptor.
Topics: Animals; Calcium; Chickens; Corpus Striatum; Dopamine; In Vitro Techniques; Indoles; Melatonin; Olfactory Bulb; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Retina; Structure-Activity Relationship; Tryptamines | 1985 |
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity.
Topics: Animals; Binding Sites; Cricetinae; Male; Mesocricetus; Quail; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Tryptamines | 1993 |
2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents.
Topics: Animals; Binding, Competitive; Calcium; Cell Membrane; Chickens; Dopamine; Iodine Radioisotopes; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Retina; Structure-Activity Relationship; Tetrahydronaphthalenes | 1993 |
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina | 1997 |
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
Topics: Animals; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Models, Molecular; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Superior Colliculi | 1997 |
1-(2-Alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues.
Topics: Animals; Binding Sites; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Melatonin; Models, Chemical; Quail; Superior Colliculi | 1997 |
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi | 1998 |
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin | 2003 |
New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Humans; Ligands; Melatonin; Protein Binding; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2 | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
High affinity specific binding of 2-[125I]iodomelatonin by spleen membrane preparations of chicken.
Topics: Animals; Chickens; Circadian Rhythm; Iodine Radioisotopes; Kinetics; Melatonin; Random Allocation; Receptors, Melatonin; Receptors, Neurotransmitter; Spleen | 1992 |
Binding characteristics and regional distribution of [125I]iodomelatonin binding sites in the brain of the human fetus.
Topics: Binding, Competitive; Brain; Brain Chemistry; Fetus; Humans; Hypothalamus; Indoles; Melatonin; Neurotransmitter Agents; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin | 1991 |
Inhibitory action of melatonin and structurally related compounds on testosterone production by mouse Leydig cells in vitro.
Topics: 5-Methoxytryptamine; Animals; Dose-Response Relationship, Drug; Indoles; Leydig Cells; Male; Melatonin; Mice; Mice, Inbred BALB C; Testosterone | 1991 |
Activation of melatonin receptor sites retarded the depletion of norepinephrine following inhibition of synthesis in the C3H/HeN mouse hypothalamus.
Topics: alpha-Methyltyrosine; Animals; Brain; Circadian Rhythm; Hypothalamus; Male; Melatonin; Methyltyrosines; Mice; Mice, Inbred C3H; Norepinephrine; Receptors, Melatonin; Receptors, Neurotransmitter; Tissue Distribution; Tryptamines | 1990 |
Reproductive effects of 6-chloromelatonin implants and/or injections in male and female Syrian hamsters (Mesocricetus auratus).
Topics: Animals; Cricetinae; Dose-Response Relationship, Drug; Drug Implants; Female; Follicle Stimulating Hormone; Genitalia; Injections, Intravenous; Luteinizing Hormone; Male; Melatonin; Mesocricetus; Organ Size; Pituitary Gland, Anterior; Prolactin | 1986 |
Melatonin-binding in the frog retina: autoradiographic and biochemical analysis.
Topics: Animals; Autoradiography; Binding Sites; Choroid; Circadian Rhythm; Darkness; Indoles; Light; Melanocytes; Melatonin; Pigment Epithelium of Eye; Radioimmunoassay; Rana pipiens; Retina; Retinal Ganglion Cells | 1986 |
Development of drugs to modify the actions of melatonin.
Topics: Animals; Circadian Rhythm; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Ovulation; Prolactin; Rats; Structure-Activity Relationship | 1986 |
Pineal methoxyindoles depress calcium uptake by rat brain synaptosomes.
Topics: 5-Methoxytryptamine; Animals; Brain; Calcium; Female; In Vitro Techniques; Indoles; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1984 |
Follicular growth and intraovarian and extraovarian oocyte release after daily injections of melatonin and 6-chloro-melatonin in the Syrian hamster.
Topics: Animals; Cricetinae; Estrus; Female; Melatonin; Mesocricetus; Oocytes; Organ Size; Ovarian Follicle; Ovary; Ovulation; Pregnancy; Uterus | 1983 |
Methoxyindoles and photoreceptor metabolism: activation of rod shedding.
Topics: Animals; In Vitro Techniques; Indoles; Melatonin; Phagocytosis; Photoreceptor Cells; Xenopus laevis | 1983 |
Natural and synthetic analogues of melatonin and related compounds. I. Effects on the reproductive system of the male Syrian hamster.
Topics: Animals; Cricetinae; Hormones; Indoles; Luteinizing Hormone; Male; Melatonin; Mesocricetus; Prolactin; Reproduction; Testis; Thyrotropin | 1983 |
Inhibition of luteinizing hormone release and ovulation by 6-chloro- and 6-fluoromelatonin.
Topics: Animals; Diestrus; Female; Half-Life; Kinetics; Luteinizing Hormone; Melatonin; Ovulation; Pregnancy; Prolactin; Rats; Structure-Activity Relationship | 1980 |
Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Benzazepines; Cells, Cultured; Chick Embryo; Cyclic AMP; GTP-Binding Proteins; Haloperidol; Inositol Phosphates; Melatonin; Models, Neurological; Neurons; Pertussis Toxin; Receptors, Cell Surface; Receptors, Dopamine D1; Receptors, Melatonin; Retina; Signal Transduction; Synaptic Transmission; Virulence Factors, Bordetella | 1995 |
Melatonin receptor-mediated stimulation of phosphoinositide breakdown in chick brain slices.
Topics: Animals; Brain; Calcium; Chickens; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Phosphatidylinositols; Receptors, Cell Surface; Receptors, Melatonin; Receptors, Serotonin; Time Factors; Type C Phospholipases | 1995 |
Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes.
Topics: 5-Methoxytryptamine; Acetates; Carbon Radioisotopes; Cholesterol; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Leukocytes, Mononuclear; Lipoproteins, LDL; Melatonin; Mevalonic Acid; Receptors, LDL; Serotonin; Tryptamines | 1994 |
Putative melatonin receptors in the male guinea pig kidney.
Topics: Animals; Binding Sites; Guinea Pigs; Kidney Cortex; Kidney Medulla; Male; Melatonin; Radioimmunoassay; Receptors, Cell Surface; Receptors, Melatonin; Subcellular Fractions | 1993 |
Specific binding of [125I]iodomelatonin in pigeon and quail spleen membrane preparations and effect with hydrocortisone-treatment.
Topics: Animals; Binding Sites; Cell Membrane; Circadian Rhythm; Columbidae; Hydrocortisone; Iodine Radioisotopes; Melatonin; Quail; Spleen | 1993 |
Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.
Topics: Adenylyl Cyclase Inhibitors; Cell Division; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Humans; Indoles; Iodine Radioisotopes; Kinetics; Melanoma; Melatonin; Nucleotides; Receptors, Melatonin; Receptors, Neurotransmitter; Tumor Cells, Cultured | 1993 |
Pulse radiolysis studies of melatonin and chloromelatonin.
Topics: Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Melatonin; Models, Chemical; Pulse Radiolysis; Superoxides | 1998 |
Effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells.
Topics: Cell Division; Dose-Response Relationship, Drug; Humans; Kynurenine; Melanoma; Melatonin; Serotonin; Tryptophan; Tumor Cells, Cultured; Uveal Neoplasms | 1998 |
Vasoconstrictor effects of various melatonin analogs on the rat tail artery in the presence of phenylephrine.
Topics: Acetamides; Animals; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Male; Melatonin; Muscle, Smooth; Nerve Endings; Norepinephrine; Perfusion; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Tail; Tryptamines; Vasoconstriction | 1999 |
Melatonin receptors in human uveal melanocytes and melanoma cells.
Topics: Acetamides; Blotting, Southern; Choroid Neoplasms; Dose-Response Relationship, Drug; Gene Expression; Humans; Melanocytes; Melanoma; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Thiazoles; Thiosemicarbazones; Tumor Cells, Cultured | 2000 |
Photophysical studies on melatonin and its receptor agonists.
Topics: Acetamides; Hematoporphyrins; Kynurenine; Luminescent Measurements; Melatonin; Oxygen; Phenalenes; Photochemistry; Polycyclic Compounds; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Spectrophotometry, Ultraviolet; Thiazoles; Thiosemicarbazones; Ultraviolet Rays | 2000 |
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs.
Topics: 5-Methoxytryptamine; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Molecular Biology; Oxidation-Reduction; Serotonin; Solubility; Structure-Activity Relationship; Superoxides; Tryptamines | 2002 |
Circadian expression of Mel1a and PL-II genes in placenta: effects of melatonin on the PL-II gene expression in the rat placenta.
Topics: Actins; Animals; Circadian Rhythm; Female; Gene Expression Regulation; Melatonin; Placenta; Placental Lactogen; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1 | 2003 |
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines | 2004 |
Effects of intrathecal injections of melatonin analogs on capsaicin-induced secondary mechanical allodynia and hyperalgesia in rats.
Topics: Administration, Topical; Afferent Pathways; Animals; Capsaicin; Disease Models, Animal; Drug Interactions; Hyperalgesia; Injections, Intramuscular; Injections, Spinal; Male; Melatonin; Neural Inhibition; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reflex; Skin; Spinal Cord; Spinal Cord Injuries; Tetrahydronaphthalenes; Tryptamines | 2004 |
Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid.
Topics: Analgesics; Analgesics, Opioid; Animals; beta-Endorphin; Binding, Competitive; Brain; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme-Linked Immunosorbent Assay; Melatonin; Mice; Naloxone; Nociceptin; Opioid Peptides; Pineal Gland; Radioligand Assay; Rats; Receptors, Opioid; Subcellular Fractions; Time Factors; Tritium | 2005 |
Melatonin decreases calcium levels in retinotectal axons of Xenopus laevis by indirect activation of group III metabotropic glutamate receptors.
Topics: Aniline Compounds; Animals; Antioxidants; Axons; Calcium; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Melatonin; Models, Neurological; Phosphinic Acids; Picrotoxin; Potassium Chloride; Pyridines; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells; Superior Colliculi; Tetrahydronaphthalenes; Xanthenes; Xenopus laevis | 2005 |
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines.
Topics: Cell Line, Tumor; Choriocarcinoma; Chorionic Gonadotropin, beta Subunit, Human; Female; Fluorescent Antibody Technique; Gene Expression; Humans; Melatonin; Nuclear Receptor Subfamily 1, Group F, Member 1; Pertussis Toxin; Placenta; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Retinoic Acid; Trans-Activators | 2006 |
Melatonin-enhanced hyperactivation of hamster sperm.
Topics: Animals; Calcium; Cells, Cultured; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serum Albumin; Sperm Motility; Spermatozoa; Stimulation, Chemical; Tetrahydronaphthalenes; Time; Tryptamines | 2008 |
Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer.
Topics: Aged; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Immunoblotting; Indenes; Male; Melatonin; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors | 2012 |