6-chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1h)-one and ethyl-acetoacetate

6-chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1h)-one has been researched along with ethyl-acetoacetate* in 1 studies

Other Studies

1 other study(ies) available for 6-chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1h)-one and ethyl-acetoacetate

Article	Year
Metal-free arylation of ethyl acetoacetate with hypervalent diaryliodonium salts: an immediate access to diverse 3-aryl-4(1H)-quinolones. The Journal of organic chemistry, 2015, Mar-06, Volume: 80, Issue:5 A clean arylation protocol of ethyl acetoacetate was developed using hypervalent diaryliodonium salts under mild and metal-free conditions. The scope of the reaction, using symmetric and unsymmetric iodonium salts with varying sterics and electronics, was examined. Further, this method has been applied for the synthesis of antimalarial compound ELQ-300, which is currently in preclinical development. Topics: Acetoacetates; Antimalarials; Iodine; Metals; Molecular Structure; Onium Compounds; Quinolines; Quinolones	2015

Article

Year

Metal-free arylation of ethyl acetoacetate with hypervalent diaryliodonium salts: an immediate access to diverse 3-aryl-4(1H)-quinolones.

The Journal of organic chemistry, 2015, Mar-06, Volume: 80, Issue:5

A clean arylation protocol of ethyl acetoacetate was developed using hypervalent diaryliodonium salts under mild and metal-free conditions. The scope of the reaction, using symmetric and unsymmetric iodonium salts with varying sterics and electronics, was examined. Further, this method has been applied for the synthesis of antimalarial compound ELQ-300, which is currently in preclinical development.

Topics: Acetoacetates; Antimalarials; Iodine; Metals; Molecular Structure; Onium Compounds; Quinolines; Quinolones

2015