Page last updated: 2024-09-02

6-chloro-2-(1-piperazinyl)pyrazine and piperidines

6-chloro-2-(1-piperazinyl)pyrazine has been researched along with piperidines in 10 studies

Compound Research Comparison

Studies
(6-chloro-2-(1-piperazinyl)pyrazine)
Trials
(6-chloro-2-(1-piperazinyl)pyrazine)
Recent Studies (post-2010)
(6-chloro-2-(1-piperazinyl)pyrazine)
Studies
(piperidines)
Trials
(piperidines)
Recent Studies (post-2010) (piperidines)
15782440,2355,22114,545

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barrett, JE; Brady, LS1
Clineschmidt, BV; Pettibone, DJ; Reiss, DR; Robinson, JL1
Barrett, JE; Mansbach, RS1
Gudelsky, GA; Koenig, JI; Meltzer, HY1
Fuller, RW; Hemrick-Luecke, SK1
Dekeyne, A; Girardon, S; Millan, MJ1
Cunningham, KA; Filip, M; McCreary, AC1
Conway, SM; Neisewander, JL; Pentkowski, NS; Pockros, LA; Ullman, TE; Zwick, KR1
Chen, W; Li, M; Qiao, J; Su, W; Sui, N; Yang, Y; Zhang, H; Zhang, Q1
Bègue, L; Bell, R; Duke, AA; Gilmore, PE; Page, D1

Other Studies

10 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and piperidines

ArticleYear
Effects of serotonin receptor agonists and antagonists on schedule-controlled behavior of squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cinanserin; Conditioning, Operant; Cyproheptadine; Electroshock; Female; Ketanserin; Male; Metergoline; Methysergide; Piperazines; Piperidines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri

1985
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperazines; Piperidines; Propranolol; Pyrazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium

1985
Effects of MK-212 (6-chloro-2[1-piperazinyl]pyrazine) on schedule-controlled behavior and their reversal by 5-HT antagonists in the pigeon.
    Neuropharmacology, 1986, Volume: 25, Issue:1

    Topics: Animals; Columbidae; Conditioning, Operant; Cues; Generalization, Stimulus; Ketanserin; Male; Metergoline; Methysergide; Piperidines; Pyrazines; Receptors, Serotonin; Reinforcement Schedule

1986
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors.
    Neuropharmacology, 1986, Volume: 25, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Ketanserin; Male; Methoxydimethyltryptamines; Pindolol; Piperidines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes

1986
Involvement of 5-HT2A receptors in the elevation of rat serum corticosterone concentrations by quipazine and MK-212.
    European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3

    Topics: Animals; Corticosterone; Fluorobenzenes; Indoles; Male; Piperidines; Pyrazines; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Urea

1996
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
    Neuropharmacology, 1999, Volume: 38, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1999
Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes.
    Behavioral neuroscience, 2003, Volume: 117, Issue:2

    Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Fenfluramine; Fluorobenzenes; Indoles; Ketanserin; Male; Piperidines; Pyrazines; Pyridines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes

2003
5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:12

    Topics: Animals; Caudate Nucleus; Cocaine; Fluorobenzenes; Gene Expression Regulation; Locomotion; Male; Piperidines; Proto-Oncogene Proteins c-fos; Putamen; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2012
Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 117

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Piperidines; Postpartum Period; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists

2014
Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands.
    Scientific reports, 2014, Jan-24, Volume: 4

    Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Male; Maze Learning; Oxazines; Piperidines; Propane; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides

2014