6-chloro-2-(1-piperazinyl)pyrazine has been researched along with lisuride in 3 studies
| Studies (6-chloro-2-(1-piperazinyl)pyrazine) | Trials (6-chloro-2-(1-piperazinyl)pyrazine) | Recent Studies (post-2010) (6-chloro-2-(1-piperazinyl)pyrazine) | Studies (lisuride) | Trials (lisuride) | Recent Studies (post-2010) (lisuride) |
|---|---|---|---|---|---|
| 157 | 8 | 24 | 756 | 80 | 31 |
| Protein | Taxonomy | 6-chloro-2-(1-piperazinyl)pyrazine (IC50) | lisuride (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.02 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.041 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.559 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0003 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.016 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0029 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0043 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0005 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.173 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.04 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.041 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.003 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.02 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0005 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.16 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0002 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0051 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dupre, A; Egan, C; Grinde, E; Hake, M; Herrick-Davis, K; Roth, BL; Teitler, M | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Appel, JB; White, FJ | 1 |
3 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and lisuride
| Article | Year |
|---|---|
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
Topics: Animals; Cell Line; Computer Simulation; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Signal Transduction; Transfection; Tritium | 2000 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
A neuropharmacological analysis of the discriminative stimulus properties of fenfluramine.
Topics: Animals; Cocaine; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hallucinogens; Lisuride; Lysergic Acid Diethylamide; Male; p-Chloroamphetamine; Piperazines; Pyrazines; Quipazine; Rats; Serotonin; Serotonin Antagonists | 1981 |