6-chloro-2-(1-piperazinyl)pyrazine has been researched along with glutamic acid in 3 studies
| Studies (6-chloro-2-(1-piperazinyl)pyrazine) | Trials (6-chloro-2-(1-piperazinyl)pyrazine) | Recent Studies (post-2010) (6-chloro-2-(1-piperazinyl)pyrazine) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 157 | 8 | 24 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | 6-chloro-2-(1-piperazinyl)pyrazine (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frølund, B; Gloriam, DE; Isberg, V; Jensen, AA; Krall, J; Krogsgaard-Larsen, P; Pedersen, MH; Plath, N; Stensbøl, TB; Wellendorph, P | 1 |
| Hurley, LM | 1 |
| Appleyard, SM; Cui, RJ; Roberts, BL; Zhao, H; Zhu, M | 1 |
3 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and glutamic acid
| Article | Year |
|---|---|
Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.
Topics: Azepines; Biological Availability; Cognition; Drug Design; HEK293 Cells; Humans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists | 2013 |
Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Chiroptera; Dose-Response Relationship, Drug; Electrodes; Electrophysiology; Evoked Potentials, Auditory; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Inferior Colliculi; Iontophoresis; Male; Pyrazines; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2006 |
Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.
Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2012 |