6-chloro-2-(1-piperazinyl)pyrazine has been researched along with apomorphine in 5 studies
| Studies (6-chloro-2-(1-piperazinyl)pyrazine) | Trials (6-chloro-2-(1-piperazinyl)pyrazine) | Recent Studies (post-2010) (6-chloro-2-(1-piperazinyl)pyrazine) | Studies (apomorphine) | Trials (apomorphine) | Recent Studies (post-2010) (apomorphine) |
|---|---|---|---|---|---|
| 157 | 8 | 24 | 9,205 | 287 | 780 |
| Protein | Taxonomy | 6-chloro-2-(1-piperazinyl)pyrazine (IC50) | apomorphine (IC50) |
|---|---|---|---|
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | 0.22 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0146 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D | Rattus norvegicus (Norway rat) | 0.4744 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.3385 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(1B) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0813 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.205 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 1.35 | |
| D | Bos taurus (cattle) | 0.3385 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benavidez, S; Carr, JA; Krobert, K; Saland, LC; Samora, A | 1 |
| Menon, MK; Vivonia, CA | 1 |
| Friedman, L; Jesberger, JA; Meltzer, HY | 1 |
| Maes, M; Meltzer, HY; Thompson, PA | 1 |
| Canto-de-Souza, A; Furuya-da-Cunha, EM; Souza, RR | 1 |
2 trial(s) available for 6-chloro-2-(1-piperazinyl)pyrazine and apomorphine
| Article | Year |
|---|---|
The effect of apomorphine, MK-212 (6-chloro-2-[1-piperazinyl]-pyrazine) and placebo on smooth pursuit gain and corrective saccades in normal subjects.
Topics: Adult; Apomorphine; Female; Humans; Male; Pursuit, Smooth; Pyrazines; Reference Values; Saccades; Serotonin Receptor Agonists | 1994 |
Effect of the placebo control condition in neuroendocrine challenge studies.
Topics: 5-Hydroxytryptophan; Antipsychotic Agents; Apomorphine; Bias; Buspirone; Data Interpretation, Statistical; Depressive Disorder; Female; Fenfluramine; Growth Hormone; Humans; Hydrocortisone; Male; Prolactin; Pyrazines; Schizophrenia; Schizophrenic Psychology; Serotonin Receptor Agonists | 1994 |
3 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and apomorphine
| Article | Year |
|---|---|
In vivo effects of serotonergic agents on alpha-melanocyte-stimulating hormone secretion.
Topics: alpha-MSH; Animals; Apomorphine; beta-Endorphin; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Male; Pituitary Gland; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin | 1991 |
Modification of apomorphine hypothermia by drugs affecting brain 5-hydroxytryptamine function.
Topics: Animals; Apomorphine; Body Temperature; Brain; Hypothermia; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred Strains; Piperazines; Pyrazines; Quipazine; Receptors, Serotonin; Serotonin Antagonists | 1981 |
Rat exposure in mice with neuropathic pain induces fear and antinociception that is not reversed by 5-HT2C receptor activation in the dorsal periaqueductal gray.
Topics: Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; Male; Mice; Microinjections; Pain Measurement; Periaqueductal Gray; Pyrazines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Sciatica; Serotonin Receptor Agonists | 2016 |