Compounds > 6-chloro-2-(1-piperazinyl)pyrazine

Page last updated: 2024-09-02

6-chloro-2-(1-piperazinyl)pyrazine and alpha-methylserotonin

6-chloro-2-(1-piperazinyl)pyrazine has been researched along with alpha-methylserotonin in 5 studies

Compound Research Comparison

Studies (6-chloro-2-(1-piperazinyl)pyrazine)	Trials (6-chloro-2-(1-piperazinyl)pyrazine)	Recent Studies (post-2010) (6-chloro-2-(1-piperazinyl)pyrazine)	Studies (alpha-methylserotonin)	Trials (alpha-methylserotonin)	Recent Studies (post-2010) (alpha-methylserotonin)
157	8	24	186	0	21

Protein Interaction Comparison

Protein	Taxonomy	6-chloro-2-(1-piperazinyl)pyrazine (IC50)	alpha-methylserotonin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)		0.0196
Alpha-2A adrenergic receptor	Bos taurus (cattle)		0.0196

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB	1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D	1
Goto, F; Obata, H; Saito, S; Sakurazawa, S; Sasaki, M; Usui, T	1
Deuchars, J; Deuchars, SA; Pierce, ML	1
Bokhan, NA; Bosker, FJ; Dröge, MJ; Ivanova, SA; Loonen, AJM; van Vliet, BJ; Volders, HH	1

Other Studies

5 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and alpha-methylserotonin

Article	Year
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature	1993
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2004
Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury. Pain, 2004, Volume: 108, Issue:1-2 Topics: Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Ligation; Lumbar Vertebrae; Male; Neuralgia; Nociceptors; Piperazines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Nerves; Spiro Compounds; Sulfonamides; Thiophenes	2004
Spontaneous rhythmogenic capabilities of sympathetic neuronal assemblies in the rat spinal cord slice. Neuroscience, 2010, Oct-27, Volume: 170, Issue:3 Topics: Action Potentials; Adrenergic Fibers; Animals; Autonomic Fibers, Preganglionic; Bicuculline; Female; Male; Periodicity; Pyrazines; Rats; Rats, Wistar; Serotonin; Spinal Cord; Tetrodotoxin	2010
Remaining Need for In Vitro Test to Elucidate 5-Hydroxytryptamine 2C Receptor Functioning. Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:4 Topics: Calcium; Digitonin; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Polymorphism, Single Nucleotide; Pyrazines; Receptor, Serotonin, 5-HT2C; Serotonin	2018