Page last updated: 2024-09-02

6-chloro-2-(1-piperazinyl)pyrazine and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

6-chloro-2-(1-piperazinyl)pyrazine has been researched along with 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole in 6 studies

Compound Research Comparison

Studies
(6-chloro-2-(1-piperazinyl)pyrazine)
Trials
(6-chloro-2-(1-piperazinyl)pyrazine)
Recent Studies (post-2010)
(6-chloro-2-(1-piperazinyl)pyrazine)
Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
157824218012

Protein Interaction Comparison

ProteinTaxonomy6-chloro-2-(1-piperazinyl)pyrazine (IC50)5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0107
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.039
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.295
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.004
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)5.4
5-hydroxytryptamine receptor 6Homo sapiens (human)0.079

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Cooper, SJ; Neill, JC1
Bethea, CL; Lorens, SA; Urban, JH; Van de Kar, LD1
Jørgensen, H; Knigge, U; Warberg, J1
Rabin, RA; Winter, JC1

Other Studies

6 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

ArticleYear
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1C receptor mediation.
    Psychopharmacology, 1989, Volume: 99, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Fenfluramine; Fluoxetine; Hypertonic Solutions; Indoles; Male; Piperazines; Pyrazines; Quinoxalines; Quipazine; Rats; Receptors, Serotonin; Serotonin

1989
Effect of selective serotonin (5-HT) agonists and 5-HT2 antagonist on prolactin secretion.
    Neuropharmacology, 1989, Volume: 28, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ergolines; Fenfluramine; Indoles; Male; Prolactin; Pyrazines; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1989
Effect of selective serotonin receptor agonists on prolactin secretion in male rats.
    Neuroendocrinology, 1993, Volume: 57, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Indoles; Male; Prolactin; Pyrazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1993
Discriminative stimulus properties of m-chlorophenylpiperazine.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: Animals; Discrimination Learning; Generalization, Stimulus; Indoles; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin Antagonists; Serotonin Receptor Agonists

1993