6-chloro-2-(1-piperazinyl)pyrazine and 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

6-chloro-2-(1-piperazinyl)pyrazine has been researched along with 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid in 2 studies

Compound Research Comparison

Studies (6-chloro-2-(1-piperazinyl)pyrazine)	Trials (6-chloro-2-(1-piperazinyl)pyrazine)	Recent Studies (post-2010) (6-chloro-2-(1-piperazinyl)pyrazine)	Studies (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid)	Trials (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid)	Recent Studies (post-2010) (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid)
157	8	24	755	2	65

Protein Interaction Comparison

Protein	Taxonomy	3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (IC50)
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	0.1139
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	0.1139

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kindler, S; Zohar, J	1
Appleyard, SM; Cui, RJ; Roberts, BL; Zhao, H; Zhu, M	1

Trials

1 trial(s) available for 6-chloro-2-(1-piperazinyl)pyrazine and 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

Article	Year
Update of the serotonergic hypothesis of obsessive compulsive disorder. Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A Topics: Double-Blind Method; Humans; Obsessive-Compulsive Disorder; Piperazines; Pyrazines; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists	1992

Other Studies

1 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

Article	Year
Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-14, Volume: 32, Issue:46 Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase	2012

Article

Year

Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-14, Volume: 32, Issue:46

Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase

2012