6-aminoquinolyl-n-hydroxysuccinimidyl-carbamate and diethyl-(ethoxymethylene)malonate

Quantification of analysis results for the suspect and non-targeted screening is essential for obtaining meaningful insight from the measurements. Ionization efficiency predictions is a possible approach to enable quantitation without standard substances. This is, however, especially challenging for the analysis carried out by combining the full scan mode either with fragmentation experiments in data-dependent or data-independent acquisition mode. Here we investigate the correlation of ionization efficiency values measured in full scan mode with the response factors measured in multiple reaction monitoring (MRM) mode for derivatized amino acids. We observe good correlation (R

Topics: Amines; Amino Acids; Aminoquinolines; Beer; Carbamates; Chromatography, Liquid; Indicators and Reagents; Malonates; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Wine