Page last updated: 2024-08-21

6-aminonicotinamide and deoxyglucose

6-aminonicotinamide has been researched along with deoxyglucose in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's1 (7.14)18.2507
2000's5 (35.71)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mehta, J; Simchowitz, L; Spilberg, I1
Cunningham, VJ; Gaitonde, MK; Murray, E1
Belfi, CA; Berger, NA; Berger, SJ; Chatterjee, S; Hirota, H1
Chatterjee, S; Gosky, D1
Bikopoulos, GJ; Ceddia, RB; Hilliker, AJ; Sweeney, G1
Adhikari, JS; Dwarakanath, BS; Varshney, R1
Dwarakanath, BS; Gupta, S; Varshney, R1
Dwarakanath, B; Jain, V; Varshney, R1
Bhardwaj, R; Dwarakanath, BS; Sharma, PK; Varshney, R1
Bhardwaj, R; Jadon, SS; Sharma, PK; Varshney, R1
Bhardwaj, R; Jadon, SP; Sharma, PK; Varshney, R1
Gordon, J; Khalili, K; Noch, E; Sariyer, IK1
Dwarakanath, BS; Sharma, PK; Varshney, R1
Sharma, PK; Varshney, R1

Other Studies

14 other study(ies) available for 6-aminonicotinamide and deoxyglucose

ArticleYear
Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:7

    Topics: 6-Aminonicotinamide; Anti-Inflammatory Agents; Antimetabolites; Aspirin; Aurothioglucose; Chemotaxis, Leukocyte; Deoxyglucose; Dose-Response Relationship, Drug; Ethylmaleimide; Free Radicals; Glycolysis; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Iodoacetates; Neutrophils; Ouabain; Oxygen; Phenylbutazone; Superoxides

1979
Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo.
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: 6-Aminonicotinamide; Amino Acids; Animals; Binding, Competitive; Brain; Deoxyglucose; Fructosephosphates; Gluconates; Glucose; Glucose-6-Phosphate; Glucose-6-Phosphate Isomerase; Glucosephosphates; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Rats, Inbred Strains; Spectrophotometry

1989
Hypersensitivity to DNA cross-linking agents associated with up-regulation of glucose-regulated stress protein GRP78.
    Cancer research, 1997, Nov-15, Volume: 57, Issue:22

    Topics: 6-Aminonicotinamide; Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Carmustine; Carrier Proteins; Cell Line; Cisplatin; Cricetinae; Deoxyglucose; DNA Repair; DNA, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Melphalan; Molecular Chaperones; Teratogens; Up-Regulation

1997
Down-regulation of topoisomerase II alpha is caused by up-regulation of GRP78.
    Biochemical and biophysical research communications, 2003, Jan-10, Volume: 300, Issue:2

    Topics: 6-Aminonicotinamide; Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Carrier Proteins; Cell Line; Cricetinae; Deoxyglucose; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Drug Resistance; Endoplasmic Reticulum Chaperone BiP; Etoposide; Heat-Shock Proteins; Molecular Chaperones; Proteins; Up-Regulation

2003
Insulin stimulates glucose metabolism via the pentose phosphate pathway in Drosophila Kc cells.
    FEBS letters, 2003, Dec-04, Volume: 555, Issue:2

    Topics: 6-Aminonicotinamide; Animals; Carbon Dioxide; Carbon Radioisotopes; Cell Line; Deoxyglucose; Drosophila melanogaster; Glucose; Glycogen; Insulin; Lactic Acid; Pentose Phosphate Pathway; Tritium

2003
Contribution of oxidative stress to radiosensitization by a combination of 2-DG and 6-AN in human cancer cell line.
    Indian journal of experimental biology, 2003, Volume: 41, Issue:12

    Topics: 6-Aminonicotinamide; Cell Line, Tumor; Deoxyglucose; Humans; Oxidative Stress; Radiation-Sensitizing Agents

2003
Radiosensitization of murine Ehrlich ascites tumor by a combination of 2-deoxy-D-glucose and 6-aminonicotinamide.
    Technology in cancer research & treatment, 2004, Volume: 3, Issue:6

    Topics: 6-Aminonicotinamide; Animals; Carcinoma, Ehrlich Tumor; Deoxyglucose; Dose-Response Relationship, Radiation; Mice; Neoplasm Transplantation; Radiation-Sensitizing Agents

2004
Radiosensitization by 6-aminonicotinamide and 2-deoxy-D-glucose in human cancer cells.
    International journal of radiation biology, 2005, Volume: 81, Issue:5

    Topics: 6-Aminonicotinamide; Antimetabolites; Apoptosis; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Death; Cell Proliferation; Deoxyglucose; DNA Damage; Glioma; Humans; Kinetics; Radiation Tolerance; Radiation-Sensitizing Agents; S Phase; Teratogens; Tumor Cells, Cultured

2005
Metabolic oxidative stress induced by a combination of 2-DG and 6-AN enhances radiation damage selectively in malignant cells via non-coordinated expression of antioxidant enzymes.
    Cancer letters, 2010, Sep-28, Volume: 295, Issue:2

    Topics: 6-Aminonicotinamide; Antioxidants; Catalase; Cell Line, Tumor; Deoxyglucose; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; NADP; Neoplasms; Oxidative Stress; Radiation Tolerance; Superoxide Dismutase

2010
A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces oxidative stress mediated selective radiosensitization of malignant cells via mitochondrial dysfunction.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2011, Volume: 32, Issue:5

    Topics: 6-Aminonicotinamide; Apoptosis; Blotting, Western; Cell Line, Tumor; Deoxyglucose; Gamma Rays; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Radiation-Sensitizing Agents

2011
A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:4

    Topics: 6-Aminonicotinamide; Apoptosis; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Checkpoints; Cell Division; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoradiotherapy; Cyclin A; Cyclin B; Cyclin-Dependent Kinases; Deoxyglucose; Flow Cytometry; G2 Phase; Humans; Neoplasms; Reactive Oxygen Species

2012
JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: 6-Aminonicotinamide; Animals; Antigens, Viral, Tumor; Antimetabolites; Brain Neoplasms; Cell Cycle Checkpoints; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Down-Regulation; Glioblastoma; Glucose; Glycolysis; Hexokinase; Humans; JC Virus; Medulloblastoma; Metabolic Networks and Pathways; Mice; Oxythiamine; Pentose Phosphate Pathway; Reactive Oxygen Species; Transaldolase

2012
Radiosensitization by 2-deoxy-D-glucose and 6-aminonicotinamide involves activation of redox sensitive ASK1-JNK/p38MAPK signaling in head and neck cancer cells.
    Free radical biology & medicine, 2012, Oct-01, Volume: 53, Issue:7

    Topics: 6-Aminonicotinamide; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferation; Deoxyglucose; Drug Synergism; Gamma Rays; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured

2012
2-Deoxy-D-glucose and 6-aminonicotinamide-mediated Nrf2 down regulation leads to radiosensitization of malignant cells via abrogation of GSH-mediated defense.
    Free radical research, 2012, Volume: 46, Issue:12

    Topics: 6-Aminonicotinamide; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Proliferation; Deoxyglucose; Down-Regulation; Glioma; Glutathione; Head and Neck Neoplasms; Humans; NF-E2-Related Factor 2; Protein Transport; Radiation-Sensitizing Agents; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Teratogens; Tumor Cells, Cultured

2012