6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide and taurine

6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide has been researched along with taurine in 23 studies

Compound Research Comparison

Studies (6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide)	Trials (6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide)	Recent Studies (post-2010) (6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide)	Studies (taurine)	Trials (taurine)	Recent Studies (post-2010) (taurine)
25	0	0	10,301	430	2,438

Protein Interaction Comparison

Protein	Taxonomy	6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide (IC50)	taurine (IC50)
Sodium- and chloride-dependent taurine transporter	Homo sapiens (human)		10

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (82.61)	18.7374
1990's	2 (8.70)	18.2507
2000's	2 (8.70)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hassessian, H; Mitsoglou, GM; Padjen, AL	1
Kimura, H; Okamoto, K; Sakai, Y	3
Palmi, M; Sgaragli, GP	2
Da Silva, AM; Gatti, PJ; Gillis, R; Holtman, JR; Namath, IJ; Souza, JD	1
Bobyock, E; Ferko, AP	1
Kontro, P; Oja, SS	1
Ente, P; Fariello, RG; Golden, GT	1
Ferko, AP	1
Ahtee, L; Vahala, ML	1
Atkinson, JG; Girard, Y; Haubrich, DR; Williams, M; Yarbrough, GG	1
Curtis, DR; Leah, JD; Peet, MJ	1
Hedner, J; Hedner, T; Jonason, J; Wessberg, P	1
Bloch, R; Bousquet, P; Feldman, J; Schwartz, J	1
Ondo, JG	1
Singh, DK; Taylor, DA; Yarbrough, GG	1
Bendesky, RJ; Martin, GE; Williams, M	1
Lewin, L; Rassin, DK; Sellström, A	1
Mathers, DA	1
Ebner, K; Engelmann, M; Landgraf, R; Lubec, G; Ludwig, M; Sabatier, N; Singewald, N; Wotjak, CT	1
Cooke, JE; Ghavanini, AA; Mathers, DA; McCarthy, SM; Puil, E	1

Reviews

2 review(s) available for 6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide and taurine

Article	Year
Pharmacological evidence for taurine as an inhibitory neurotransmitter in the cerebellum. Progress in clinical and biological research, 1985, Volume: 179 Topics: Animals; Benzothiadiazines; Calcium; Cerebellum; Chlorides; Dendrites; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neurotransmitter Agents; Purkinje Cells; Taurine	1985
The role and mechanism of action of taurine in mammalian thermoregulation. Progress in clinical and biological research, 1985, Volume: 179 Topics: Animals; Benzothiadiazines; Body Temperature Regulation; Calcium; Central Nervous System; Fenclonine; Motor Activity; Rabbits; Rats; Serotonin; Structure-Activity Relationship; Taurine; Verapamil	1985

Other Studies

21 other study(ies) available for 6-aminomethyl-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide and taurine

Article	Year
Further evidence in support of taurine as a mediator of synaptic transmission in the frog spinal cord. Brain research, 1989, May-29, Volume: 488, Issue:1-2 Topics: Action Potentials; Animals; Benzothiadiazines; In Vitro Techniques; Membrane Potentials; Rana catesbeiana; Rana pipiens; Ranidae; Spinal Cord; Taurine	1989
Comparative cardiorespiratory effects produced by taurine and glycine applied to the ventral surface of the medulla. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Animals; Benzothiadiazines; Blood Pressure; Cats; Female; Glycine; Heart Rate; Male; Medulla Oblongata; Receptors, GABA-A; Respiration; Strychnine; Taurine; Tidal Volume	1985
Effect of taurine on ethanol-induced sleep time in mice genetically bred for differences in ethanol sensitivity. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3 Topics: Animals; Benzothiadiazines; Brain; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Pentobarbital; Sleep; Taurine	1988
Co-operativity in sodium-independent taurine binding to brain membranes in the mouse. Neuroscience, 1987, Volume: 23, Issue:2 Topics: Animals; Benzothiadiazines; Binding, Competitive; Brain; Kinetics; Mice; Sodium; Synaptosomes; Taurine	1987
The epileptogenic action of 6-aminomethyl-3-methyl,1-4H-1,2,6-benzothiadiazine-1,1-diazide hydrochloride (TAG): non-specific versus specific antitaurine pathogenesis. Brain research, 1986, Aug-13, Volume: 380, Issue:1 Topics: Action Potentials; Animals; Benzothiadiazines; Cerebral Cortex; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Male; Neurons; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Taurine	1986
Ethanol-induced sleep time: interaction with taurine and a taurine antagonist. Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:2 Topics: Animals; Benzothiadiazines; Brain; Ethanol; Male; Mice; Mice, Inbred Strains; Sleep; Taurine; Time Factors	1987
[Antagonism by taurine of hyperthermia induced in rabbits by 6-aminomethyl-4H,1,2,4-benzothiadiazine 1,1-dioxide (AMBD) and by calcium antagonists]. Bollettino della Societa italiana di biologia sperimentale, 1985, May-30, Volume: 61, Issue:5 Topics: Animals; Benzothiadiazines; Body Temperature Regulation; Fever; Injections, Intraventricular; Rabbits; Taurine; Verapamil	1985
Taurine and its derivatives alter brain dopamine metabolism similarly to GABA in mice and rats. Progress in clinical and biological research, 1985, Volume: 179 Topics: Animals; Apomorphine; Benzothiadiazines; Brain; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Mice; Rats; Taurine	1985
Evidence for taurine as an inhibitory neurotransmitter in cerebellar stellate interneurons: selective antagonism by TAG (6-aminomethyl-3-methyl-4H,1,2,4-benzothiadiazine-1,1-dioxide). Brain research, 1983, Apr-11, Volume: 265, Issue:1 Topics: Animals; Benzothiadiazines; Cerebellum; Guinea Pigs; Interneurons; Neurotransmitter Agents; Purkinje Cells; Synaptic Transmission; Taurine	1983
Aminomethyl-1,2,4-benzothiadiazines as potential analogues of gamma-aminobutyric acid. Unexpected discovery of a taurine antagonist. Journal of medicinal chemistry, 1982, Volume: 25, Issue:2 Topics: 4-Aminobutyrate Transaminase; Animals; Benzothiadiazines; Brain; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes; Taurine	1982
Lack of specificity of a "taurine antagonist". Brain research, 1982, Jul-22, Volume: 244, Issue:1 Topics: Amino Acids; Animals; Benzothiadiazines; Cats; Electric Stimulation; Ganglia, Spinal; Interneurons; Neural Inhibition; Receptors, Amino Acid; Receptors, Cell Surface; Taurine	1982
Effects of taurine and a taurine antagonist on some respiratory and cardiovascular parameters. Life sciences, 1983, Oct-24, Volume: 33, Issue:17 Topics: Animals; Benzothiadiazines; Cardiovascular System; Male; Rats; Rats, Inbred Strains; Respiration; Taurine	1983
TAG antagonises the central cardiovascular effects of taurine. European journal of pharmacology, 1984, Feb-17, Volume: 98, Issue:2 Topics: Animals; Benzothiadiazines; Blood Pressure; Brain; Cats; Dose-Response Relationship, Drug; Heart Rate; Muscimol; Taurine	1984
The antagonistic action of 6-aminomethyl-3-methyl-4H,1,2, 4-benzothiadiazine-1,1-dioxide (TAG) on the prolactin-releasing action of taurine. Life sciences, 1984, Aug-06, Volume: 35, Issue:6 Topics: Animals; Benzothiadiazines; Catheters, Indwelling; Injections, Intraventricular; Luteinizing Hormone; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Taurine	1984
Neuropharmacological characterization of a taurine antagonist. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3 Topics: Action Potentials; Amino Acids; Animals; Benzothiadiazines; Bufo marinus; Central Nervous System; In Vitro Techniques; Iontophoresis; Male; Purkinje Cells; Rats; Rats, Inbred Strains; Spinal Cord; Taurine	1981
Antagonistic action of 6-aminomethyl-3-methyl-4H, 1,2,4-benzothiadiazine-1, 1-dioxide (TAG), and evidence for a transmitter role of taurine in stellate interneurons in the cerebellum. Progress in clinical and biological research, 1983, Volume: 125 Topics: Animals; Benzothiadiazines; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Guinea Pigs; Purkinje Cells; Taurine	1983
Further evidence for selective antagonism of taurine by 6-aminomethyl-3-methyl-4H-1,2,4-benzothiadiazine-1,1-dioxide. Brain research, 1981, Dec-21, Volume: 229, Issue:2 Topics: Animals; Benzothiadiazines; Dominance, Cerebral; Dose-Response Relationship, Drug; Female; Humans; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Taurine	1981
Net taurine transport and its inhibition by a taurine antagonist. Neurochemical research, 1994, Volume: 19, Issue:3 Topics: Animals; Benzothiadiazines; Biological Transport; Brain; Female; Kinetics; Rats; Rats, Sprague-Dawley; Rubidium; Rubidium Radioisotopes; Scintillation Counting; Taurine; Tritium	1994
Effects of the benzothiadiazine TAG on channel activation at mammalian glycine receptors. Neuroscience letters, 1993, Jan-04, Volume: 149, Issue:1 Topics: Animals; Benzothiadiazines; Chloride Channels; Electrophysiology; Glycine; Membrane Proteins; Mice; Mice, Inbred Strains; Neurons; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Taurine	1993
Taurine selectively modulates the secretory activity of vasopressin neurons in conscious rats. The European journal of neuroscience, 2001, Volume: 14, Issue:7 Topics: Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Bicuculline; Consciousness; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Neurons; Oxytocin; Rats; Rats, Wistar; Receptors, GABA-A; Stress, Physiological; Supraoptic Nucleus; Swimming; Taurine; Vasopressins	2001
Effects of the beta-amino acid antagonist TAG on thalamocortical inhibition. Neuropharmacology, 2009, Volume: 56, Issue:8 Topics: Animals; Benzothiadiazines; beta-Alanine; Bicuculline; Dose-Response Relationship, Drug; Glycine; Inhibitory Postsynaptic Potentials; Kynurenic Acid; Membrane Potentials; Patch-Clamp Techniques; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Strychnine; Taurine; Thalamic Nuclei	2009