Compounds > 6-amino-2-n-pentylthiobenzothiazole
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6-amino-2-n-pentylthiobenzothiazole and clotrimazole

6-amino-2-n-pentylthiobenzothiazole has been researched along with clotrimazole in 2 studies

*Clotrimazole: An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. [MeSH]

*Clotrimazole: An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. [MeSH]

Compound Research Comparison

Studies
(6-amino-2-n-pentylthiobenzothiazole)		Trials
(6-amino-2-n-pentylthiobenzothiazole)		Recent Studies (post-2010)
(6-amino-2-n-pentylthiobenzothiazole)		Studies
(clotrimazole)		Trials
(clotrimazole)		Recent Studies (post-2010) (clotrimazole)
11002,005299503

Protein Interaction Comparison

ProteinTaxonomy6-amino-2-n-pentylthiobenzothiazole (IC50)clotrimazole (IC50)
Intermediate conductance calcium-activated potassium channel protein 4Homo sapiens (human)0.1667
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.59
Transient receptor potential cation channel subfamily M member 2Homo sapiens (human)3
Bile salt export pumpHomo sapiens (human)10
Glucocorticoid receptorHomo sapiens (human)3.258
ATP-dependent translocase ABCB1Mus musculus (house mouse)3.5
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)3.258
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)7.936
ATP-dependent translocase ABCB1Homo sapiens (human)4.9
Cytochrome P450 3A4Homo sapiens (human)0.0406
Adenosine receptor A3Homo sapiens (human)4.752
Muscarinic acetylcholine receptor M1Homo sapiens (human)6.869
AromataseHomo sapiens (human)0.0018
Cytochrome P450 2C9 Homo sapiens (human)0.016
Beta-3 adrenergic receptorHomo sapiens (human)7.208
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)4.752
Alpha-2B adrenergic receptorHomo sapiens (human)8.159
Potassium-transporting ATPase subunit betaSus scrofa (pig)5.2
Potassium-transporting ATPase alpha chain 1Sus scrofa (pig)5.2
Muscarinic acetylcholine receptor M3Homo sapiens (human)9.928
Glycine receptor subunit betaRattus norvegicus (Norway rat)3.258
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.8
D(1A) dopamine receptorHomo sapiens (human)9.017
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)6
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.59
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)3.258
Sodium-dependent noradrenaline transporter Homo sapiens (human)7.936
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)3.258
Thromboxane-A synthase Homo sapiens (human)0.014
Histamine H2 receptorHomo sapiens (human)5.165
C-X-C chemokine receptor type 1Homo sapiens (human)5.9677
Vasopressin V2 receptorHomo sapiens (human)2.6059
Sodium-dependent serotonin transporterHomo sapiens (human)5.76
Cytochrome P450 2C19Homo sapiens (human)0.016
Mu-type opioid receptorHomo sapiens (human)1.802
D(3) dopamine receptorHomo sapiens (human)2.647
Delta-type opioid receptorHomo sapiens (human)4.978
Kappa-type opioid receptorHomo sapiens (human)6.303
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)4.752
C-C chemokine receptor type 4Homo sapiens (human)1.6
Transitional endoplasmic reticulum ATPaseHomo sapiens (human)1.4
Sodium-dependent dopamine transporter Homo sapiens (human)5.581
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.0199
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.59
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)0.29
Lanosterol 14-alpha demethylaseHomo sapiens (human)0.13
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)5.9
Bile acid receptorHomo sapiens (human)3.24

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bujdáková, H; Klobusický, M; Múcková, M; Sidóová, E1
Bujdáková, H; Dierich, MP; Gruber, A; Klobusický, M; Kurisková, S; Langgartner, M; Lell, CP; Spötl, L; Würzner, R1

Other Studies

2 other study(ies) available for 6-amino-2-n-pentylthiobenzothiazole and clotrimazole

ArticleYear
Efficacy of 6-amino-2-n-pentylthiobenzothiazole on Trichophyton in vitro and in vivo.
    Mycopathologia, 1995, Volume: 130, Issue:3

    Topics: Animals; Antifungal Agents; Benzothiazoles; Clotrimazole; Guinea Pigs; Ketoconazole; Microbial Sensitivity Tests; Thiazoles; Tinea; Trichophyton

1995
The influence of subinhibitory concentrations of conventional and experimental antifungal drugs on the expression of the iC3b binding protein in Candida albicans strains during filamentation.
    FEMS immunology and medical microbiology, 1999, Volume: 26, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Clotrimazole; Complement C3b; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Fluconazole; Humans; Immunoblotting; Microbial Sensitivity Tests; Nystatin; Receptors, Complement 3b; Rosette Formation; Sheep; Species Specificity; Thiazoles; Tunicamycin

1999