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6,6'-dicorynomycolyl trehalose and lipid a

6,6'-dicorynomycolyl trehalose has been researched along with lipid a in 10 studies

Compound Research Comparison

Studies
(6,6'-dicorynomycolyl trehalose)
Trials
(6,6'-dicorynomycolyl trehalose)
Recent Studies (post-2010)
(6,6'-dicorynomycolyl trehalose)
Studies
(lipid a)
Trials
(lipid a)
Recent Studies (post-2010) (lipid a)
27173,9011251,143

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McGee, JM; Patten, MR; Price, JA; Snyder, D1
Cease, KB; Hankenson, FC; Oscherwitz, J; Yu, F1
Berhanu, A; Brown, LL; Grosenbach, DW; Honeychurch, KM; Hruby, DE; Jones, KF; King, DS; Kirkwood-Watts, DL; Krupkin, AK; Lund, SA; Vandermay, E; Warren, TK; Weimers, W; Wilson, RL1
Acquafredda, A; Brandonisio, O; Fasanella, A; Gradoni, L; Mitolo, V; Panaro, MA; Scaltrito, D; Trotta, T1
Ali, N; Bhowmick, S; Das, A; Ravindran, R1
Ali, N; Maji, M; Ravindran, R1
Ali, N; Maji, M; Mazumder, S1
Ali, N; Das, A1
Bolduc, DL; Elliott, TB; Fatanmi, OO; Kiang, JG; Ledney, GD; Newman, VL; Romaine, PL; Singh, VK; Wise, SY1
Dyevoich, AM; Haas, KM; Haro, MA; Phipps, JP1

Trials

1 trial(s) available for 6,6'-dicorynomycolyl trehalose and lipid a

ArticleYear
Comparison between three adjuvants for a vaccine against canine leishmaniasis: In vitro evaluation of macrophage killing ability.
    Comparative immunology, microbiology and infectious diseases, 2010, Volume: 33, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; BCG Vaccine; Cell Wall Skeleton; Cord Factors; Dog Diseases; Dogs; Female; Humans; Leishmania infantum; Leishmaniasis; Leishmaniasis Vaccines; Leukocytes, Mononuclear; Lipid A; Macrophages; Male; Time Factors

2010

Other Studies

9 other study(ies) available for 6,6'-dicorynomycolyl trehalose and lipid a

ArticleYear
Effects of the adjuvant MPL + TDM on tumor challenge in the B16 mouse melanoma model.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Cord Factors; Lipid A; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Tumor Cells, Cultured

1996
Low-dose intraperitoneal Freund's adjuvant: toxicity and immunogenicity in mice using an immunogen targeting amyloid-beta peptide.
    Vaccine, 2006, Apr-05, Volume: 24, Issue:15

    Topics: Adjuvants, Immunologic; Alum Compounds; Alzheimer Vaccines; Amyloid beta-Peptides; Animals; Antibodies; Body Weight; Cord Factors; Female; Freund's Adjuvant; Injections, Intraperitoneal; Leukocyte Count; Lipid A; Mice; Mice, Inbred C57BL; Models, Animal; Spleen

2006
Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge.
    Journal of virology, 2008, Volume: 82, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; Cord Factors; Epitopes, B-Lymphocyte; Escherichia coli; Female; Humans; Interferon-gamma; Lipid A; Lymphocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Neutralization Tests; Poloxalene; Smallpox; Smallpox Vaccine; Spleen; Survival Analysis; Vaccines, Subunit; Vaccinia virus; Viral Envelope Proteins; Viral Proteins; Viral Structural Proteins

2008
Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis.
    BMC microbiology, 2010, Jun-24, Volume: 10

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Antigens, Protozoan; BCG Vaccine; Cord Factors; Female; Immunity, Humoral; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Mice; Time Factors

2010
Vaccination with liposomal leishmanial antigens adjuvanted with monophosphoryl lipid-trehalose dicorynomycolate (MPL-TDM) confers long-term protection against visceral leishmaniasis through a human administrable route.
    Molecular pharmaceutics, 2012, Jan-01, Volume: 9, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Cells, Cultured; Chemical Phenomena; Cord Factors; Immunity, Active; Immunity, Cellular; Immunologic Memory; Injections, Subcutaneous; Interferon-gamma; Interleukin-4; Leishmania donovani; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Liposomes; Liver; Mice; Mice, Inbred BALB C; Phospholipids; Specific Pathogen-Free Organisms; Spleen

2012
Potentiating effects of MPL on DSPC bearing cationic liposomes promote recombinant GP63 vaccine efficacy: high immunogenicity and protection.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:12

    Topics: Adjuvants, Immunologic; Animals; Cord Factors; Cytokines; Disease Models, Animal; Female; Humans; Injections, Subcutaneous; Leishmania donovani; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Liposomes; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Nitric Oxide; Phosphatidylcholines; Th1 Cells; Vaccination; Vaccines, Synthetic

2011
Combining cationic liposomal delivery with MPL-TDM for cysteine protease cocktail vaccination against Leishmania donovani: evidence for antigen synergy and protection.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:8

    Topics: Animals; Antigens, Protozoan; Cations; Cord Factors; Cricetinae; Cysteine Proteases; Disease Models, Animal; Drug Delivery Systems; Leishmania donovani; Leishmaniasis; Lipid A; Liposomes; Mesocricetus; Protozoan Vaccines

2014
Combined immunomodulator and antimicrobial therapy eliminates polymicrobial sepsis and modulates cytokine production in combined injured mice.
    International journal of radiation biology, 2015, Volume: 91, Issue:9

    Topics: Amoxicillin; Animals; Anti-Infective Agents; Bacterial Infections; Chemokines; Cord Factors; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; Gamma Rays; Growth Substances; Immunologic Factors; Levofloxacin; Lipid A; Mice; Radiation Injuries, Experimental; Sepsis; Skin; Wound Infection

2015
Activation of B-1 Cells Promotes Tumor Cell Killing in the Peritoneal Cavity.
    Cancer research, 2019, 01-01, Volume: 79, Issue:1

    Topics: Animals; B-Lymphocyte Subsets; Cord Factors; Female; Immunity, Innate; Immunoglobulin M; Lectins, C-Type; Lipid A; Lymphocyte Activation; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred A; Mice, Inbred C57BL; Peritoneal Cavity; Peritoneal Neoplasms; Toll-Like Receptors

2019