6,6'-dicorynomycolyl trehalose has been researched along with cord factors in 26 studies
| Studies (6,6'-dicorynomycolyl trehalose) | Trials (6,6'-dicorynomycolyl trehalose) | Recent Studies (post-2010) (6,6'-dicorynomycolyl trehalose) | Studies (cord factors) | Trials (cord factors) | Recent Studies (post-2010) (cord factors) |
|---|---|---|---|---|---|
| 27 | 1 | 7 | 492 | 3 | 103 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Brook, I; Elliott, TB; Ledney, GD; Madonna, GS; Moore, MM | 2 |
| Elliott, TB; Jackson, WE; Ledney, GD; Madonna, GS; Moore, MM | 1 |
| Imasato, H; Ioneda, T; Procópio, J; Tabak, M | 1 |
| Datta, AK; Takayama, K | 1 |
| McGee, JM; Patten, MR; Price, JA; Snyder, D | 1 |
| Landauer, MR; Ledney, GD; McChesney, DG | 1 |
| Azuma, I; Garcia, DM; Hata, K; Imagawa, H; Koike, Y; Mitobe, M; Nishizawa, M; Nobuchi, Y; Watanabe, R; Yamada, H; Yoo, YC | 1 |
| Barber, MR; Fayrer-Hosken, RA | 1 |
| Davis, HD; Kumar, KS; Landauer, MR; Weiss, JF | 1 |
| Elliott, TB; Harding, RA; Henderson, PL; Landauer, MR; Ledney, GD; Tom, SP; Vigneulle, RM | 1 |
| Andréau, K; Bayan, N; Chaby, R; Chami, M; Daffé, M; Houssin, C; Lemassu, A; Petit, JF; Puech, V | 1 |
| Brand, S; Kalinowski, J; Niehaus, K; Pühler, A | 1 |
| Cease, KB; Hankenson, FC; Oscherwitz, J; Yu, F | 1 |
| Azuma, I; Barbier-Chassefière, V; Imagawa, H; Nishizawa, M; Papy-Garcia, D; Petit, E; Yamamoto, H | 1 |
| Actor, JK; Guidry, TV; Hunter, RL | 1 |
| Berhanu, A; Brown, LL; Grosenbach, DW; Honeychurch, KM; Hruby, DE; Jones, KF; King, DS; Kirkwood-Watts, DL; Krupkin, AK; Lund, SA; Vandermay, E; Warren, TK; Weimers, W; Wilson, RL | 1 |
| Acquafredda, A; Brandonisio, O; Fasanella, A; Gradoni, L; Mitolo, V; Panaro, MA; Scaltrito, D; Trotta, T | 1 |
| Ali, N; Bhowmick, S; Das, A; Ravindran, R | 1 |
| Ali, N; Maji, M; Ravindran, R | 1 |
| Ali, N; Maji, M; Mazumder, S | 1 |
| Himeno, S; Imagawa, H; Inoue, M; Nagahama, M; Nakano, M; Nishizawa, M; Oda, M; Sakurai, J; Setsu, K; Shibutani, M; Watanabe, N; Yabiku, K; Yamamoto, H | 1 |
| Ali, N; Das, A | 1 |
| Bolduc, DL; Elliott, TB; Fatanmi, OO; Kiang, JG; Ledney, GD; Newman, VL; Romaine, PL; Singh, VK; Wise, SY | 1 |
| Dyevoich, AM; Haas, KM; Haro, MA; Phipps, JP | 1 |
| Hu, X; Huang, D; Li, H; Li, Y; Liu, Z; Ma, W; Tan, X; Wang, X; Wang, Y; Xu, D; Zhang, D; Zhao, G | 1 |
1 review(s) available for 6,6'-dicorynomycolyl trehalose and cord factors
| Article | Year |
|---|---|
Therapy of infections in mice irradiated in mixed neutron/photon fields and inflicted with wound trauma: a review of current work.
Topics: Adjuvants, Immunologic; Animals; Cobalt Radioisotopes; Cord Factors; Female; Gamma Rays; Klebsiella Infections; Klebsiella pneumoniae; Mice; Neutrons; Radiation Injuries, Experimental; Wound Infection | 1991 |
1 trial(s) available for 6,6'-dicorynomycolyl trehalose and cord factors
| Article | Year |
|---|---|
Comparison between three adjuvants for a vaccine against canine leishmaniasis: In vitro evaluation of macrophage killing ability.
Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; BCG Vaccine; Cell Wall Skeleton; Cord Factors; Dog Diseases; Dogs; Female; Humans; Leishmania infantum; Leishmaniasis; Leishmaniasis Vaccines; Leukocytes, Mononuclear; Lipid A; Macrophages; Male; Time Factors | 2010 |
24 other study(ies) available for 6,6'-dicorynomycolyl trehalose and cord factors
| Article | Year |
|---|---|
Synthetic trehalose dicorynomycolate and antimicrobials increase survival from sepsis in mice immunocompromised by radiation and trauma.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Cord Factors; Female; Immunocompromised Host; Mice; Mice, Inbred C3H; Radiation Injuries, Experimental; Wound Infection; Wounds and Injuries | 1992 |
Treatment of mice with sepsis following irradiation and trauma with antibiotics and synthetic trehalose dicorynomycolate (S-TDCM).
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Bacteria; Cord Factors; Drug Therapy, Combination; Female; Gamma Rays; Gentamicins; Immunity; Injections; Mice; Mice, Inbred C3H; Ofloxacin; Oxacillin; Wound Infection | 1991 |
Effect of low mole fraction of trehalose dicorynomycolate from Corynebacterium diphtheriae on water permeability and electrical capacitance of lipid bilayer membranes.
Topics: Cord Factors; Corynebacterium diphtheriae; Electric Conductivity; Glycolipids; Lipid Bilayers; Membranes, Artificial; Permeability; Water | 1990 |
Isolation and purification of trehalose 6-mono- and 6,6'-di-corynomycolates from Corynebacterium matruchotii. Structural characterization by 1H NMR.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Cord Factors; Corynebacterium; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure | 1993 |
Effects of the adjuvant MPL + TDM on tumor challenge in the B16 mouse melanoma model.
Topics: Adjuvants, Immunologic; Animals; Cord Factors; Lipid A; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Tumor Cells, Cultured | 1996 |
Synthetic trehalose dicorynomycolate (S-TDCM): behavioral effects and radioprotection.
Topics: Adjuvants, Immunologic; Animals; Behavior, Animal; Cord Factors; Drinking; Eating; Female; Mice; Motor Activity; Radiation-Protective Agents | 1997 |
Inhibitory effect of trehalose dimycolate (TDM) and its stereoisometric derivatives, trehalose dicorynomycolates (TDCMs), with low toxicity on lung metastasis of tumour cells in mice.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Colonic Neoplasms; Cord Factors; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Chemical; Neoplasm Metastasis; Stereoisomerism | 1999 |
Evaluation of somatic and reproductive immunotoxic effects of the porcine zona pellucida vaccination.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antibody Formation; Contraception, Immunologic; Cord Factors; Cross Reactions; Dogs; Egg Proteins; Enzyme-Linked Immunosorbent Assay; Female; Fertility; Horses; Immunoenzyme Techniques; Immunoglobulin G; Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Swine; Vaccines; Zona Pellucida; Zona Pellucida Glycoproteins | 2000 |
Behavioral toxicity of selected radioprotectors.
Topics: 16,16-Dimethylprostaglandin E2; Adjuvants, Immunologic; Amifostine; Animals; Caffeine; Central Nervous System Stimulants; Cord Factors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucans; Interleukin-1; Leukotriene C4; Male; Mice; Motor Activity; Phospholipids; Platelet Activating Factor; Radiation-Protective Agents; Sulfhydryl Compounds | 1992 |
Survival of irradiated mice treated with WR-151327, synthetic trehalose dicorynomycolate, or ofloxacin.
Topics: Adjuvants, Immunologic; Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Cord Factors; Female; Gamma Rays; Gram-Negative Bacterial Infections; Liver; Mice; Mice, Inbred Strains; Neutrons; Ofloxacin; Organothiophosphorus Compounds; Radiation Injuries, Experimental; Radiation Tolerance; Radiation-Protective Agents; Survival Rate | 1994 |
Priming and activation of mouse macrophages by trehalose 6,6'-dicorynomycolate vesicles from Corynebacterium glutamicum.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Cord Factors; Corynebacterium; Female; Macrophage Activation; Macrophages, Peritoneal; Mice | 2002 |
Identification and functional analysis of six mycolyltransferase genes of Corynebacterium glutamicum ATCC 13032: the genes cop1, cmt1, and cmt2 can replace each other in the synthesis of trehalose dicorynomycolate, a component of the mycolic acid layer of
Topics: Arabidopsis Proteins; Carrier Proteins; Cord Factors; Corynebacterium; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; Gene Deletion; Genome, Bacterial; Mycolic Acids; Phylogeny; Ubiquitin-Protein Ligases | 2003 |
Low-dose intraperitoneal Freund's adjuvant: toxicity and immunogenicity in mice using an immunogen targeting amyloid-beta peptide.
Topics: Adjuvants, Immunologic; Alum Compounds; Alzheimer Vaccines; Amyloid beta-Peptides; Animals; Antibodies; Body Weight; Cord Factors; Female; Freund's Adjuvant; Injections, Intraperitoneal; Leukocyte Count; Lipid A; Mice; Mice, Inbred C57BL; Models, Animal; Spleen | 2006 |
Efficient syntheses of a series of trehalose dimycolate (TDM)/trehalose dicorynomycolate (TDCM) analogues and their interleukin-6 level enhancement activity in mice sera.
Topics: Animals; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Cord Factors; Interleukin-6; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Sequence Data; Mycobacterium tuberculosis; Stimulation, Chemical; Trehalose | 2007 |
Mycobacterial glycolipid trehalose 6,6'-dimycolate-induced hypersensitive granulomas: contribution of CD4+ lymphocytes.
Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; Cord Factors; Granuloma; Interferon-gamma; Interleukin-12; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; T-Lymphocyte Subsets | 2007 |
Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; Cord Factors; Epitopes, B-Lymphocyte; Escherichia coli; Female; Humans; Interferon-gamma; Lipid A; Lymphocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Neutralization Tests; Poloxalene; Smallpox; Smallpox Vaccine; Spleen; Survival Analysis; Vaccines, Subunit; Vaccinia virus; Viral Envelope Proteins; Viral Proteins; Viral Structural Proteins | 2008 |
Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Antigens, Protozoan; BCG Vaccine; Cord Factors; Female; Immunity, Humoral; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Mice; Time Factors | 2010 |
Vaccination with liposomal leishmanial antigens adjuvanted with monophosphoryl lipid-trehalose dicorynomycolate (MPL-TDM) confers long-term protection against visceral leishmaniasis through a human administrable route.
Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Cells, Cultured; Chemical Phenomena; Cord Factors; Immunity, Active; Immunity, Cellular; Immunologic Memory; Injections, Subcutaneous; Interferon-gamma; Interleukin-4; Leishmania donovani; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Liposomes; Liver; Mice; Mice, Inbred BALB C; Phospholipids; Specific Pathogen-Free Organisms; Spleen | 2012 |
Potentiating effects of MPL on DSPC bearing cationic liposomes promote recombinant GP63 vaccine efficacy: high immunogenicity and protection.
Topics: Adjuvants, Immunologic; Animals; Cord Factors; Cytokines; Disease Models, Animal; Female; Humans; Injections, Subcutaneous; Leishmania donovani; Leishmaniasis Vaccines; Leishmaniasis, Visceral; Lipid A; Liposomes; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Nitric Oxide; Phosphatidylcholines; Th1 Cells; Vaccination; Vaccines, Synthetic | 2011 |
Development of vizantin, a safe immunostimulant, based on the structure-activity relationship of trehalose-6,6'-dicorynomycolate.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Cell Line, Tumor; Cord Factors; Glycolipids; Humans; In Vitro Techniques; Lung Neoplasms; Macrophages; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phagocytosis; Stereoisomerism; Structure-Activity Relationship; Trehalose; Xenograft Model Antitumor Assays | 2013 |
Combining cationic liposomal delivery with MPL-TDM for cysteine protease cocktail vaccination against Leishmania donovani: evidence for antigen synergy and protection.
Topics: Animals; Antigens, Protozoan; Cations; Cord Factors; Cricetinae; Cysteine Proteases; Disease Models, Animal; Drug Delivery Systems; Leishmania donovani; Leishmaniasis; Lipid A; Liposomes; Mesocricetus; Protozoan Vaccines | 2014 |
Combined immunomodulator and antimicrobial therapy eliminates polymicrobial sepsis and modulates cytokine production in combined injured mice.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Bacterial Infections; Chemokines; Cord Factors; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; Gamma Rays; Growth Substances; Immunologic Factors; Levofloxacin; Lipid A; Mice; Radiation Injuries, Experimental; Sepsis; Skin; Wound Infection | 2015 |
Activation of B-1 Cells Promotes Tumor Cell Killing in the Peritoneal Cavity.
Topics: Animals; B-Lymphocyte Subsets; Cord Factors; Female; Immunity, Innate; Immunoglobulin M; Lectins, C-Type; Lipid A; Lymphocyte Activation; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred A; Mice, Inbred C57BL; Peritoneal Cavity; Peritoneal Neoplasms; Toll-Like Receptors | 2019 |
Improve L-isoleucine production in Corynebacterium glutamicum WM001 by destructing the biosynthesis of trehalose dicorynomycolate.
Topics: Cord Factors; Corynebacterium glutamicum; Isoleucine; Trehalose | 2023 |