6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid has been researched along with tretinoin in 6 studies
| Studies (6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid) | Trials (6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid) | Recent Studies (post-2010) (6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid) | Studies (tretinoin) | Trials (tretinoin) | Recent Studies (post-2010) (tretinoin) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 23,654 | 1,083 | 6,085 |
| Protein | Taxonomy | 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid (IC50) | tretinoin (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.18 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.275 | |
| Retinoic acid receptor alpha | Homo sapiens (human) | 2.2542 | |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Retinoic acid receptor beta | Homo sapiens (human) | 0.7537 | |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.0057 | |
| Retinoic acid receptor gamma | Homo sapiens (human) | 0.0064 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | 0.004 | |
| Retinoic acid receptor beta | Mus musculus (house mouse) | 0.005 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.576 | |
| Nuclear receptor ROR-alpha | Homo sapiens (human) | 0.1995 | |
| Alpha-synuclein | Homo sapiens (human) | 3 | |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.5233 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.358 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.35 | |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | 0.1995 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | 0.82 | |
| 60 kDa chaperonin | Escherichia coli | 6.7 | |
| 10 kDa chaperonin | Escherichia coli | 6.7 | |
| Nuclear receptor ROR-beta | Homo sapiens (human) | 0.1259 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, WR; Dawson, MI; Derdzinski, KA; Frenking, G; Hobbs, PD; Jetten, AM; Loew, GH; Napoli, JL; Sani, BP; Williams, JB | 1 |
| Chan, RL; Chao, WR; Dawson, MI; Derdzinski, K; Gruber, J; Hobbs, PD; Schiff, LJ; Smith, S; Thies, RW | 1 |
| Bernardon, JM; Charpentier, B; Eustache, J; Martin, B; Michel, S; Millois, C; Shroot, B | 1 |
| Chao, WR; Dawson, MI; Feng, KC; Fontana, JA; Hobbs, PD; Jong, L; Pan, C; Xiao, D; Zhang, XK | 1 |
| Arumugarajah, S; Bhuiyan, M; Chao, WR; Dawson, MI; Farhana, L; Fontana, JA; Fukushi, J; Han, YH; Harris, DL; Hobbs, PD; Jong, L; Liu, G; Mustelin, T; Patel, BB; Sani, BP; Schiff, LJ; Stallcup, WB; Su, Y; Tautz, L; Waleh, N; Xia, Z; Ye, M; Zhang, XK | 1 |
| Hong, WK; Lotan, D; Lotan, R; Oridate, N; Wan, H | 1 |
6 other study(ies) available for 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid and tretinoin
| Article | Year |
|---|---|
Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids.
Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Chick Embryo; Male; Molecular Conformation; Rabbits; Retinoids; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1989 |
Conformationally restricted retinoids.
Topics: Animals; Cell Differentiation; Chemical Phenomena; Chemistry; Female; Keratins; Mice; Organ Culture Techniques; Ornithine Decarboxylase Inhibitors; Papilloma; Retinoids; Skin; Structure-Activity Relationship; Trachea; Vitamin A Deficiency | 1984 |
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes.
Topics: Animals; Cell Differentiation; Magnetic Resonance Spectroscopy; Mice; Receptors, Retinoic Acid; Recombinant Proteins; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; Structure-Activity Relationship; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured | 1995 |
4-[3-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)phenyl]benzoic acid and heterocyclic-bridged analogues are novel retinoic acid receptor subtype and retinoid X receptor alpha agonists.
Topics: Benzoates; Heterocyclic Compounds; Humans; Naphthalenes; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Tumor Cells, Cultured | 2000 |
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and
Topics: Adamantane; Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Cinnamates; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endothelial Cells; Humans; In Vitro Techniques; Microcirculation; Protein Tyrosine Phosphatases; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Cytoplasmic and Nuclear; Retinoids; Stereoisomerism | 2007 |
Overexpression of retinoic acid receptor beta in head and neck squamous cell carcinoma cells increases their sensitivity to retinoid-induced suppression of squamous differentiation by retinoids.
Topics: 3T3 Cells; Alitretinoin; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Drug Resistance; Head and Neck Neoplasms; Humans; Mice; Naphthalenes; Neoplasm Proteins; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; RNA, Neoplasm; Transcription Factor AP-1; Transfection; Tretinoin; Tumor Cells, Cultured | 1999 |