Page last updated: 2024-09-04

5-vinyl-2'-deoxyuridine and fluorouracil

5-vinyl-2'-deoxyuridine has been researched along with fluorouracil in 2 studies

Compound Research Comparison

Studies (5-vinyl-2'-deoxyuridine)	Trials (5-vinyl-2'-deoxyuridine)	Recent Studies (post-2010) (5-vinyl-2'-deoxyuridine)	Studies (fluorouracil)	Trials (fluorouracil)	Recent Studies (post-2010) (fluorouracil)
13	1	4	45,562	9,307	14,663

Protein Interaction Comparison

Protein	Taxonomy	fluorouracil (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.32
Thymidylate synthase	Mus musculus (house mouse)	1.58
Aromatase	Homo sapiens (human)	0.63

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE	1
Banken, L; Bellibas, SE; Brivet, B; Bush, ED; Chamorey, E; Kircher, C; Milano, G; Nave, S; Patel, I; Renée, N	1

Trials

1 trial(s) available for 5-vinyl-2'-deoxyuridine and fluorouracil

Article	Year
Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Deoxycytidine; Deoxyuridine; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Leukocytes, Mononuclear; Male; Models, Chemical; Placebos; Time Factors; Uracil	2004

Article

Year

Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Deoxycytidine; Deoxyuridine; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Leukocytes, Mononuclear; Male; Models, Chemical; Placebos; Time Factors; Uracil

2004

Other Studies

1 other study(ies) available for 5-vinyl-2'-deoxyuridine and fluorouracil

Article	Year
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set. Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7 Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship	2007